Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys. - Wikidata - awgldk - TriplyDB

Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.

Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.

http://www.wikidata.org/entity/Q33554807

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Behavioral effects of a synthetic agonist selective for nociceptin/orphanin FQ peptide receptors in monkeys Functional plasticity of the N/OFQ-NOP receptor system determines analgesic properties of NOP receptor agonists An integrated perspective on diabetic, alcoholic, and drug-induced neuropathy, etiology, and treatment in the US.Long-lasting antinociceptive spinal effects in primates of the novel nociceptin/orphanin FQ receptor agonist UFP-112.Operant nociception in nonhuman primates.The role of central gastrin-releasing peptide and neuromedin B receptors in the modulation of scratching behavior in rats The effects of nociceptin/orphanin FQ receptor agonist Ro 64-6198 and diazepam on antinociception and remifentanil self-administration in rhesus monkeys Beneficial effects of co-treatment with dextromethorphan on prenatally methadone-exposed offspring Neuraxial opioid-induced itch and its pharmacological antagonism Supraspinal actions of nociceptin/orphanin FQ, morphine and substance P in regulating pain and itch in non-human primates.Spinal antinociceptive effects of the novel NOP receptor agonist PWT2-nociceptin/orphanin FQ in mice and monkeys Characterisation of the Novel Mixed Mu-NOP Peptide Ligand Dermorphin-N/OFQ (DeNo).Roles of μ-opioid receptors and nociceptin/orphanin FQ peptide receptors in buprenorphine-induced physiological responses in primates.[Dmt1]N/OFQ(1-13)-NH2: a potent nociceptin/orphanin FQ and opioid receptor universal agonist.The therapeutic potential of nociceptin/orphanin FQ receptor agonists as analgesics without abuse liability.Characterization of the Discriminative Stimulus Effects of a NOP Receptor Agonist Ro 64-6198 in Rhesus Monkeys.Nociceptin/Orphanin FQ Receptor Structure, Signaling, Ligands, Functions, and Interactions with Opioid Systems.Effects of spinally administered bifunctional nociceptin/orphanin FQ peptide receptor/μ-opioid receptor ligands in mouse models of neuropathic and inflammatory pain Central N/OFQ-NOP Receptor System in Pain Modulation.Nociceptin Opioid Receptor (NOP) as a Therapeutic Target: Progress in Translation from Preclinical Research to Clinical Utility.Anti-inflammatory effect of dual nociceptin and opioid receptor agonist, BU08070, in experimental colitis in mice Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonist Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain.Recently patented and promising ORL-1 ligands: where have we been and where are we going?UFP-112 a potent and long-lasting agonist selective for the Nociceptin/Orphanin FQ receptor.Cebranopadol: novel dual opioid/NOP receptor agonist analgesic.N/OFQ system in brain areas of nerve-injured mice: its role in different aspects of neuropathic pain.Targeting multiple opioid receptors - improved analgesics with reduced side effects?Plasma concentrations of nociceptin/orphanin FQ: comparison of levels after general and neuraxial anesthesia for arthroscopic knee surgery.Pharmacological studies on the NOP and opioid receptor agonist PWT2-[Dmt1]N/OFQ(1-13).Antihyperalgesic, Antiallodynic, and Antinociceptive Effects of Cebranopadol, a Novel Potent Nociceptin/Orphanin FQ and Opioid Receptor Agonist, after Peripheral and Central Administration in Rodent Models of Neuropathic Pain.Synthesis, Biological Evaluation, and SAR Studies of 14β-phenylacetyl Substituted 17-cyclopropylmethyl-7, 8-dihydronoroxymorphinones Derivatives: Ligands With Mixed NOP and Opioid Receptor Profile Nociceptin/orphanin FQ receptor ligands and translational challenges: focus on cebranopadol as an innovative analgesic

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P2860

Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.

http://www.wikidata.org/entity/Q33554807

description

2009 nî lūn-bûn

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2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2009 թվականի փետրվարին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.

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Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.

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Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.

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type

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Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.

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Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.

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Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.

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Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.

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Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.

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Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.

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J.JPAIN.2008.11.006

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The Journal of Pain

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Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.

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Norah N Naughton

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Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

Highly potent nociceptin analog containing the Arg-Lys triple repeat

The nociceptin/orphanin FQ receptor: a target with broad therapeutic potential

Dose-related opposite modulation by nociceptin/orphanin FQ of substance P nociception in the nociceptors and spinal cord

Effects of intrathecally administered nociceptin/orphanin FQ in monkeys: behavioral and mass spectrometric studies.

Psychophysical and physiological evidence for parallel afferent pathways mediating the sensation of itch.

In vitro and in vivo pharmacological characterization of J-113397, a potent and selective non-peptidyl ORL1 receptor antagonist.

The itch-producing agents histamine and cowhage activate separate populations of primate spinothalamic tract neurons.

Orphanin FQ inhibits capsaicin-induced thermal nociception in monkeys by activation of peripheral ORL1 receptors

Intrathecal opioids for combined spinal-epidural analgesia during labour.

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