Mechanisms of FSH synthesis: what we know, what we don't, and why you should care.
about
Fox tales: regulation of gonadotropin gene expression by forkhead transcription factorsFollicle-stimulating hormone synthesis and fertility depend on SMAD4 and FOXL2.Normal gonadotropin production and fertility in gonadotrope-specific Bmpr1a knockout mice.Gonadotrope-specific deletion of Dicer results in severely suppressed gonadotropins and fertility defects.β-catenin stabilization in gonadotropes impairs FSH synthesis in male mice in vivo.Conditional knockout of the androgen receptor in gonadotropes reveals crucial roles for androgen in gonadotropin synthesis and surge in female mice.Growth differentiation factor 9 (GDF9) forms an incoherent feed-forward loop modulating follicle-stimulating hormone β-subunit (FSHβ) gene expression.Follicle-stimulating hormone synthesis and fertility are intact in mice lacking SMAD3 DNA binding activity and SMAD2 in gonadotrope cells.Impaired fertility and FSH synthesis in gonadotrope-specific Foxl2 knockout miceFOXO1/3 depletion in granulosa cells alters follicle growth, death and regulation of pituitary FSH.NR5A2 regulates Lhb and Fshb transcription in gonadotrope-like cells in vitro, but is dispensable for gonadotropin synthesis and fertility in vivo.Modeling and high-throughput experimental data uncover the mechanisms underlying Fshb gene sensitivity to gonadotropin-releasing hormone pulse frequency.Homer1 alternative splicing is regulated by gonadotropin-releasing hormone and modulates gonadotropin gene expression.GATA2-induced silencing and LIM-homeodomain protein-induced activation are mediated by a bi-functional response element in the rat GnRH receptor gene.SMADs and FOXL2 synergistically regulate murine FSHbeta transcription via a conserved proximal promoter elementA novel model for development, organization, and function of gonadotropes in fish pituitary.Differentially expressed miRNAs after GnRH treatment and their potential roles in FSH regulation in porcine anterior pituitary cellThe Local Control of the Pituitary by Activin Signaling and Modulation.Effect of cyanotoxins on the hypothalamic-pituitary-gonadal axis in male adult mouse.Synthesis and secretion of gonadotropins including structure-function correlates.Short-term energy deprivation alters activin a and follistatin but not inhibin B levels of lean healthy women in a leptin-independent manner.Dioxin silences gonadotropin expression in perinatal pups by inducing histone deacetylases: a new insight into the mechanism for the imprinting of sexual immaturity by dioxin.Cell-type specific modulation of pituitary cells by activin, inhibin and follistatin.Ontogeny of the ovary in polycystic ovary syndrome.Polygenic sex determination in the cichlid fish Astatotilapia burtoni.Anti-Müllerian hormone: a new actor of sexual dimorphism in pituitary gonadotrope activity before puberty.Anatomical and functional gonadotrope networks in the teleost pituitary.Gonadotropins activate oncogenic pathways to enhance proliferation in normal mouse ovarian surface epithelium.Androgen receptor drives transcription of rat PACAP in gonadotrope cellsGnRH-Induced Ca(2+) Signaling Patterns and Gonadotropin Secretion in Pituitary Gonadotrophs. Functional Adaptations to Both Ordinary and Extraordinary Physiological Demands.Forkhead box O1 is a repressor of basal and GnRH-induced Fshb transcription in gonadotropes.GnRH pulse frequency-dependent differential regulation of LH and FSH gene expressionOutside the box signaling: secreted factors modulate GnRH receptor-mediated gonadotropin regulation.Characterization of Gonadotrope Secretoproteome Identifies Neurosecretory Protein VGF-derived Peptide Suppression of Follicle-stimulating Hormone Gene Expression.α-Actinin4 nuclear translocation mediates gonadotropin-releasing hormone stimulation of follicle-stimulating hormone β-subunit gene transcription in LβT2 cells.Follicle-stimulating hormone levels in female workers exposed to urban pollutants.Gonadotropin regulation by pulsatile GnRH: Signaling and gene expression.The increased expression of follicle-stimulating hormone leads to a decrease of fecundity in transgenic Large White female pigs.SMAD3 Regulates Follicle-stimulating Hormone Synthesis by Pituitary Gonadotrope Cells in Vivo.Assessment of ovarian function after chemotherapy in women with early and locally advanced breast cancer from Serbia.
P2860
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P2860
Mechanisms of FSH synthesis: what we know, what we don't, and why you should care.
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2010 nî lūn-bûn
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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2010 թվականի ապրիլին հրատարակված գիտական հոդված
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2010年の論文
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2010年論文
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2010年論文
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2010年論文
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2010年論文
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2010年論文
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2010年论文
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name
Mechanisms of FSH synthesis: what we know, what we don't, and why you should care.
@ast
Mechanisms of FSH synthesis: what we know, what we don't, and why you should care.
@en
Mechanisms of FSH synthesis: what we know, what we don't, and why you should care.
@nl
type
label
Mechanisms of FSH synthesis: what we know, what we don't, and why you should care.
@ast
Mechanisms of FSH synthesis: what we know, what we don't, and why you should care.
@en
Mechanisms of FSH synthesis: what we know, what we don't, and why you should care.
@nl
prefLabel
Mechanisms of FSH synthesis: what we know, what we don't, and why you should care.
@ast
Mechanisms of FSH synthesis: what we know, what we don't, and why you should care.
@en
Mechanisms of FSH synthesis: what we know, what we don't, and why you should care.
@nl
P2093
P1476
Mechanisms of FSH synthesis: what we know, what we don't, and why you should care.
@en
P2093
Daniel J Bernard
Jérôme Fortin
Pankaj Lamba
P304
P356
10.1016/J.FERTNSTERT.2010.03.034
P407
P577
2010-04-18T00:00:00Z