Enhancements of screening collections to address areas of unmet medical need: an industry perspective.
about
Fine-tuning multiprotein complexes using small moleculesFeatures of protein-protein interactions that translate into potent inhibitors: topology, surface area and affinityExpanding the number of 'druggable' targets: non-enzymes and protein-protein interactionsUltrafast shape recognition: method and applicationsA High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase InhibitorsPlate-based diversity subset screening generation 2: an improved paradigm for high-throughput screening of large compound filesNatural products as sources of new drugs over the 30 years from 1981 to 2010NMR approaches in structure-based lead discovery: recent developments and new frontiers for targeting multi-protein complexesRecent trends and observations in the design of high-quality screening collections.Biology-oriented synthesis.Hierarchical virtual screening for the discovery of new molecular scaffolds in antibacterial hit identificationDruggable chemical space and enumerative combinatorics.Quantifying structure and performance diversity for sets of small molecules comprising small-molecule screening collections.The chemistry and pharmacology of privileged pyrroloquinazolines.Selecting, Acquiring, and Using Small Molecule Libraries for High-Throughput Screening.Matching the power of high throughput screening to the chemical diversity of natural productsTowards pharmacological intervention in inositol pyrophosphate signalling.Scaffold Diversity Synthesis and Its Application in Probe and Drug Discovery.Bioactive Natural Product and Superacid Chemistry for Lead Compound Identification: A Case Study of Selective hCA III and L-Type Ca2+ Current Inhibitors for Hypotensive Agent Discovery.Direct Synthesis of Highly Substituted Pyrroles and Dihydropyrroles Using Linear Selective Hydroacylation Reactions.Combining organometallic reagents, the sulfur dioxide surrogate DABSO, and amines: a one-pot preparation of sulfonamides, amenable to array synthesis.Impact of high-throughput screening in biomedical research.SistematX, an Online Web-Based Cheminformatics Tool for Data Management of Secondary Metabolites.Design and Implementation of High-Throughput Screening Assays.Synthesis of molecular frameworks containing two distinct heterocycles connected in a single molecule with enhanced three-dimensional shape diversity.Diastereoselective synthesis of novel heterocyclic scaffolds through tandem Petasis 3-component/intramolecular Diels-Alder and ROM-RCM reactions.A biosynthesis-inspired approach to over twenty diverse natural product-like scaffolds.Discovery of Phloeophagus Beetles as a Source of Pseudomonas Strains That Produce Potentially New Bioactive Substances and Description of Pseudomonas bohemica sp. nov.Solid-phase Synthesis of Combinatorial 2,4-Disubstituted-1,3,5-Triazine via Amine Nucleophilic ReactionInsights into the development of chemical probes for RNA
P2860
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P2860
Enhancements of screening collections to address areas of unmet medical need: an industry perspective.
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Enhancements of screening coll ...... need: an industry perspective.
@ast
Enhancements of screening coll ...... need: an industry perspective.
@en
Enhancements of screening coll ...... need: an industry perspective.
@nl
type
label
Enhancements of screening coll ...... need: an industry perspective.
@ast
Enhancements of screening coll ...... need: an industry perspective.
@en
Enhancements of screening coll ...... need: an industry perspective.
@nl
prefLabel
Enhancements of screening coll ...... need: an industry perspective.
@ast
Enhancements of screening coll ...... need: an industry perspective.
@en
Enhancements of screening coll ...... need: an industry perspective.
@nl
P1476
Enhancements of screening coll ...... need: an industry perspective.
@en
P2093
Ricardo Macarron
P304
P356
10.1016/J.CBPA.2010.03.024
P50
P577
2010-04-21T00:00:00Z