Podocytic PKC-alpha is regulated in murine and human diabetes and mediates nephrin endocytosis. - Wikidata - awgldk - TriplyDB

Podocytic PKC-alpha is regulated in murine and human diabetes and mediates nephrin endocytosis.

Podocytic PKC-alpha is regulated in murine and human diabetes and mediates nephrin endocytosis.

http://www.wikidata.org/entity/Q33564333

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A Systems Biology Overview on Human Diabetic Nephropathy: From Genetic Susceptibility to Post-Transcriptional and Post-Translational Modifications Podocyte endocytosis in the regulation of the glomerular filtration barrier The function of endocytosis in podocytes Membrane trafficking in podocyte health and disease Inhibitory Effect of Serotonin Antagonist on Leukocyte-Endothelial Interactions In Vivo and In Vitro A novel domain regulating degradation of the glomerular slit diaphragm protein podocin in cell culture systems.Activation of protein kinase C-α and Src kinase increases urea transporter A1 α-2, 6 sialylation.Vascular endothelial growth factor receptor 2 direct interaction with nephrin links VEGF-A signals to actin in kidney podocytes Osmolarity and glucose differentially regulate aldose reductase activity in cultured mouse podocytes.Drug discovery in focal and segmental glomerulosclerosis Endocytic Trafficking at the Mature Podocyte Slit Diaphragm.Sorting Nexin 9 facilitates podocin endocytosis in the injured podocyte.Anion exchanger 1 in red blood cells and kidney: Band 3's in a pod.VEGF and podocytes in diabetic nephropathy.Role of protein kinase C in podocytes and development of glomerular damage in diabetic nephropathy.An update: the role of Nephrin inside and outside the kidney.PACSIN2 accelerates nephrin trafficking and is up-regulated in diabetic kidney disease.Podocyte-actin dynamics in health and disease.Dual inhibition of classical protein kinase C-α and protein kinase C-β isoforms protects against experimental murine diabetic nephropathy.CIN85 Deficiency Prevents Nephrin Endocytosis and Proteinuria in Diabetes.Effects of insulin and high glucose on mobilization of slo1 BKCa channels in podocytes.The BAR domain protein PICK1 regulates cell recognition and morphogenesis by interacting with Neph proteins Podocin is translocated to cytoplasm in puromycin aminonucleoside nephrosis rats and in poor-prognosis patients with IgA nephropathy.aPKCλ maintains the integrity of the glomerular slit diaphragm through trafficking of nephrin to the cell surface.Diacylglycerol Kinase alpha is Involved in the Vitamin E-Induced Amelioration of Diabetic Nephropathy in Mice.PKC alpha mediates beta-arrestin2-dependent nephrin endocytosis in hyperglycemia.Def-6, a novel regulator of small GTPases in podocytes, acts downstream of atypical protein kinase C (aPKC) λ/ι.Amelioration of diabetic nephropathy by oral administration of d-α-tocopherol and its mechanisms.Kidney-targeted inhibition of protein kinase C-α ameliorates nephrotoxic nephritis with restoration of mitochondrial dysfunction.Nephrin Signaling in the Podocyte: An Updated View of Signal Regulation at the Slit Diaphragm and Beyond.Proteinuric Kidney Diseases: A Podocyte's Slit Diaphragm and Cytoskeleton Approach

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P2860

Podocytic PKC-alpha is regulated in murine and human diabetes and mediates nephrin endocytosis.

http://www.wikidata.org/entity/Q33564333

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Podocytic PKC-alpha is regulat ...... mediates nephrin endocytosis.

@ast

Podocytic PKC-alpha is regulat ...... mediates nephrin endocytosis.

@en

Podocytic PKC-alpha is regulat ...... mediates nephrin endocytosis.

@nl

type

label

Podocytic PKC-alpha is regulat ...... mediates nephrin endocytosis.

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Podocytic PKC-alpha is regulat ...... mediates nephrin endocytosis.

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Podocytic PKC-alpha is regulat ...... mediates nephrin endocytosis.

@nl

prefLabel

Podocytic PKC-alpha is regulat ...... mediates nephrin endocytosis.

@ast

Podocytic PKC-alpha is regulat ...... mediates nephrin endocytosis.

@en

Podocytic PKC-alpha is regulat ...... mediates nephrin endocytosis.

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JOURNAL.PONE.0010185

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P1476

Podocytic PKC-alpha is regulat ...... mediates nephrin endocytosis.

@en

P2093

Beina Teng

http://www.w3.org/2001/XMLSchema#string

Friedrich Modde

http://www.w3.org/2001/XMLSchema#string

Irini Tossidou

http://www.w3.org/2001/XMLSchema#string

Jan Menne

http://www.w3.org/2001/XMLSchema#string

Jan U Becker

http://www.w3.org/2001/XMLSchema#string

Joon-Keun Park

http://www.w3.org/2001/XMLSchema#string

Michael Leitges

http://www.w3.org/2001/XMLSchema#string

Nelli Shushakova

http://www.w3.org/2001/XMLSchema#string

P2860

Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome

NEPH1 defines a novel family of podocin interacting proteins

Nephrin is specifically located at the slit diaphragm of glomerular podocytes

Diminished loss of proteoglycans and lack of albuminuria in protein kinase C-alpha-deficient diabetic mice

Serine and threonine phosphorylation of the low density lipoprotein receptor-related protein by protein kinase Calpha regulates endocytosis and association with adaptor molecules

Nephrin and Neph1 co-localize at the podocyte foot process intercellular junction and form cis hetero-oligomers

The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death

Functional PKC in vivo analysis using deficient mouse models

Knockout of PKC alpha enhances insulin signaling through PI3K

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

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e10185

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scholarly article

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10.1371/JOURNAL.PONE.0010185

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