Optimization of duplex stability and terminal asymmetry for shRNA design.
about
Accelerating cancer modeling with RNAi and nongermline genetically engineered mouse models.Improved siRNA/shRNA functionality by mismatched duplex.ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling.Mini-clusters with mean probabilities for identifying effective siRNAs.Optimization of Critical Hairpin Features Allows miRNA-based Gene Knockdown Upon Single-copy Transduction.Designing highly active siRNAs for therapeutic applications.Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells.Molecular genetic mechanisms of allelic specific regulation of murine Comt expressionNext-generation libraries for robust RNA interference-based genome-wide screens.Optimized models for design of efficient miR30-based shRNAs.Identification of novel cancer therapeutic targets using a designed and pooled shRNA library screenEnhancing potency of siRNA targeting fusion genes by optimization outside of target sequence.Knockdown of aberrantly upregulated aryl hydrocarbon receptor reduces tumor growth and metastasis of MDA-MB-231 human breast cancer cell line.Dynamic lineage analysis of embryonic morphogenesis using transgenic quail and 4D multispectral imaging.Selection of the most potent specific on/off adaptor-hepatitis delta virus ribozymes for use in gene targeting.Efficient downregulation of multiple mRNA targets with a single shRNA-expressing lentiviral vector.Molecular Properties, Functional Mechanisms, and Applications of Sliced siRNA.A boost for the emerging field of RNA nanotechnologySequence characteristics define trade-offs between on-target and genome-wide off-target hybridization of oligoprobes.
P2860
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P2860
Optimization of duplex stability and terminal asymmetry for shRNA design.
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Optimization of duplex stability and terminal asymmetry for shRNA design.
@ast
Optimization of duplex stability and terminal asymmetry for shRNA design.
@en
Optimization of duplex stability and terminal asymmetry for shRNA design.
@nl
type
label
Optimization of duplex stability and terminal asymmetry for shRNA design.
@ast
Optimization of duplex stability and terminal asymmetry for shRNA design.
@en
Optimization of duplex stability and terminal asymmetry for shRNA design.
@nl
prefLabel
Optimization of duplex stability and terminal asymmetry for shRNA design.
@ast
Optimization of duplex stability and terminal asymmetry for shRNA design.
@en
Optimization of duplex stability and terminal asymmetry for shRNA design.
@nl
P2093
P2860
P1433
P1476
Optimization of duplex stability and terminal asymmetry for shRNA design.
@en
P2093
Aleksey Y Ogurtsov
Alexey N Spiridonov
Olga V Matveeva
Pål Saetrom
Vladimir A Nemtsov
Yibin Kang
Yury D Nechipurenko
P2860
P304
P356
10.1371/JOURNAL.PONE.0010180
P407
P577
2010-04-20T00:00:00Z