A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist.

A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist.

Item
http://www.wikidata.org/entity/Q33565721
Fibroblast Growth Factor Signaling in Metabolic RegulationA dominant-negative FGF1 mutant (the R50E mutant) suppresses tumorigenesis and angiogenesisProinflammatory secreted phospholipase A2 type IIA (sPLA-IIA) induces integrin activation through direct binding to a newly identified binding site (site 2) in integrins αvβ3, α4β1, and α5β1.Enhanced Expression of Integrin αvβ3 Induced by TGF-β Is Required for the Enhancing Effect of Fibroblast Growth Factor 1 (FGF1) in TGF-β-Induced Epithelial-Mesenchymal Transition (EMT) in Mammary Epithelial CellsInsulin-like growth factor (IGF) signaling requires αvβ3-IGF1-IGF type 1 receptor (IGF1R) ternary complex formation in anchorage independence, and the complex formation does not require IGF1R and Src activationAn integrin binding-defective mutant of insulin-like growth factor-1 (R36E/R37E IGF1) acts as a dominant-negative antagonist of the IGF1 receptor (IGF1R) and suppresses tumorigenesis but still binds to IGF1R.Crosstalk between insulin-like growth factor (IGF) receptor and integrins through direct integrin binding to IGF1.The integrin-binding defective FGF2 mutants potently suppress FGF2 signalling and angiogenesis.Direct binding to integrins and loss of disulfide linkage in interleukin-1β (IL-1β) are involved in the agonistic action of IL-1β.Secreted Phospholipase A2 Type IIA (sPLA2-IIA) Activates Integrins in an Allosteric Manner.
P2860

A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist.

Item
http://www.wikidata.org/entity/Q33565721
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist.
@ast
A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist.
@en
A novel fibroblast growth factor-1
@nl
type
label
A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist.
@ast
A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist.
@en
A novel fibroblast growth factor-1
@nl
prefLabel
A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist.
@ast
A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist.
@en
A novel fibroblast growth factor-1
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist.
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0010273
P407
P433
P478
P50
P577
P5875
P698
P932