Development of homogeneous luminescence assays for histone demethylase catalysis and binding.
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High-throughput screening to identify inhibitors of lysine demethylases8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase InhibitorsLinking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylasesPlant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone DemethylasesHuman UTY(KDM6C) Is a Male-specific N -Methyl Lysyl DemethylaseDevelopment and application of a fluoride-detection-based fluorescence assay for γ-butyrobetaine hydroxylaseInhibition of 2-oxoglutarate dependent oxygenasesScreen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistanceEpigenetic assays for chemical biology and drug discovery.The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1Development of homogeneous nonradioactive methyltransferase and demethylase assays targeting histone H3 lysine 4.Methods for Activity Analysis of the Proteins that Regulate Histone MethylationConfiguration of a high-content imaging platform for hit identification and pharmacological assessment of JMJD3 demethylase enzyme inhibitors.Identification of catechols as histone-lysine demethylase inhibitors.Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.A selective inhibitor and probe of the cellular functions of Jumonji C domain-containing histone demethylases.A cell-permeable ester derivative of the JmjC histone demethylase inhibitor IOX1Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitorDocking and Linking of Fragments To Discover Jumonji Histone Demethylase Inhibitors.Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.Screening for compounds that modulate epigenetic regulation of the transcriptome: an overview.The methylproteome and the intracellular methylation network.KDM4 histone demethylase inhibitors for anti-cancer agents: a patent review.Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.Histone modifying enzymes: novel disease biomarkers and assay development.Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion.5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.Is JmjC oxygenase catalysis limited to demethylation?Demonstrating enhanced throughput of RapidFire mass spectrometry through multiplexing using the JmjD2d demethylase as a model system.Conference scene: 2nd cancer epigenetics conference.Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7.Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials.Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7Linking of 2-Oxoglutarate and Substrate Binding Sites Enables Potent and Highly Selective Inhibition of JmjC Histone Demethylases
P2860
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P2860
Development of homogeneous luminescence assays for histone demethylase catalysis and binding.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
Development of homogeneous lum ...... thylase catalysis and binding.
@ast
Development of homogeneous lum ...... thylase catalysis and binding.
@en
Development of homogeneous lum ...... thylase catalysis and binding.
@nl
type
label
Development of homogeneous lum ...... thylase catalysis and binding.
@ast
Development of homogeneous lum ...... thylase catalysis and binding.
@en
Development of homogeneous lum ...... thylase catalysis and binding.
@nl
prefLabel
Development of homogeneous lum ...... thylase catalysis and binding.
@ast
Development of homogeneous lum ...... thylase catalysis and binding.
@en
Development of homogeneous lum ...... thylase catalysis and binding.
@nl
P2093
P2860
P50
P356
P1476
Development of homogeneous lum ...... ethylase catalysis and binding
@en
P2093
Anthony Tumber
Michelle Daniel
Tom D Heightman
Udo Oppermann
P2860
P356
10.1016/J.AB.2010.04.030
P407
P577
2010-05-21T00:00:00Z