Jnk2 effects on tumor development, genetic instability and replicative stress in an oncogene-driven mouse mammary tumor model. - Wikidata - awgldk - TriplyDB

Jnk2 effects on tumor development, genetic instability and replicative stress in an oncogene-driven mouse mammary tumor model.

Jnk2 effects on tumor development, genetic instability and replicative stress in an oncogene-driven mouse mammary tumor model.

http://www.wikidata.org/entity/Q33573421

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JNK signalling in cancer: in need of new, smarter therapeutic targets Co-Targeting of JNK and HUNK in Resistant HER2-Positive Breast Cancer JNK2 downregulation promotes tumorigenesis and chemoresistance by decreasing p53 stability in bladder cancer JNK1 phosphorylation of Cdt1 inhibits recruitment of HBO1 histone acetylase and blocks replication licensing in response to stress Role of JNK in a Trp53-dependent mouse model of breast cancer.Gene expression analysis of mammary tissue during fetal bud formation and growth in two pig breeds--indications of prenatal initiation of postnatal phenotypic differences Klf4 is a transcriptional regulator of genes critical for EMT, including Jnk1 (Mapk8).c-Jun N-terminal kinase 2 (JNK2) enhances cell migration through epidermal growth factor substrate 8 (EPS8).c-Jun N-terminal Kinase 2 Regulates Multiple Receptor Tyrosine Kinase Pathways in Mouse Mammary Tumor Growth and Metastasis.Paracrine WNT5A Signaling Inhibits Expansion of Tumor-Initiating Cells.Role of JNK in mammary gland development and breast cancer.c-Jun N-terminal kinase 2 prevents luminal cell commitment in normal mammary glands and tumors by inhibiting p53/Notch1 and breast cancer gene 1 expression.In vivo gene manipulation reveals the impact of stress-responsive MAPK pathways on tumor progression.c-Jun N-terminal kinase-mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forks Development of JNK2-selective peptide inhibitors that inhibit breast cancer cell migration JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate.Differential regulation of c-Jun protein plays an instrumental role in chemoresistance of cancer cells.Linking JNK Activity to the DNA Damage Response.JNK signaling is needed to tolerate chromosomal instability JNK inhibitors as anti-inflammatory and neuroprotective agents.The 2 Faces of JNK Signaling in Cancer.Priming and potentiation of DNA damage response by fibronectin in human colon cancer cells and tumor-derived myofibroblasts.Neddylation controls basal MKK7 kinase activity in breast cancer cells.Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma.IL-17RC is critically required to maintain baseline A20 production to repress JNK isoform-dependent tumor-specific proliferation A c-Jun N-terminal kinase inhibitor, JNK-IN-8, sensitizes triple negative breast cancer cells to lapatinib.Conflicting evidence for the role of JNK as a target in breast cancer cell proliferation: Comparisons between pharmacological inhibition and selective shRNA knockdown approaches.Stress signaling in breast cancer cells induces matrix components that promote chemoresistant metastasis

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P2860

Jnk2 effects on tumor development, genetic instability and replicative stress in an oncogene-driven mouse mammary tumor model.

http://www.wikidata.org/entity/Q33573421

description

2010 nî lūn-bûn

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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2010 թվականի մայիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Jnk2 effects on tumor developm ...... ven mouse mammary tumor model.

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Jnk2 effects on tumor developm ...... ven mouse mammary tumor model.

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Jnk2 effects on tumor developm ...... ven mouse mammary tumor model.

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Jnk2 effects on tumor developm ...... ven mouse mammary tumor model.

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Jnk2 effects on tumor developm ...... ven mouse mammary tumor model.

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Jnk2 effects on tumor developm ...... ven mouse mammary tumor model.

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Jnk2 effects on tumor developm ...... ven mouse mammary tumor model.

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Azadeh Nasrazadani

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Carla L Van Den Berg

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Jamye F O'Neal

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Lynn E Heasley

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Michael A Cantrell

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Nancy D Ebelt

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Peila Chen

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Tracy L Vandenbroek

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P2860

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1

The human checkpoint sensor and alternative DNA clamp Rad9-Rad1-Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery

Replication protein A-mediated recruitment and activation of Rad17 complexes

An interaction between DNA ligase I and proliferating cell nuclear antigen: implications for Okazaki fragment synthesis and joining

Lost in transcription: p21 repression, mechanisms, and consequences

JNK phosphorylates paxillin and regulates cell migration

Focusing on foci: H2AX and the recruitment of DNA-damage response factors

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy

A central role for JNK in obesity and insulin resistance

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