Jnk2 effects on tumor development, genetic instability and replicative stress in an oncogene-driven mouse mammary tumor model.
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JNK signalling in cancer: in need of new, smarter therapeutic targetsCo-Targeting of JNK and HUNK in Resistant HER2-Positive Breast CancerJNK2 downregulation promotes tumorigenesis and chemoresistance by decreasing p53 stability in bladder cancerJNK1 phosphorylation of Cdt1 inhibits recruitment of HBO1 histone acetylase and blocks replication licensing in response to stressRole of JNK in a Trp53-dependent mouse model of breast cancer.Gene expression analysis of mammary tissue during fetal bud formation and growth in two pig breeds--indications of prenatal initiation of postnatal phenotypic differencesKlf4 is a transcriptional regulator of genes critical for EMT, including Jnk1 (Mapk8).c-Jun N-terminal kinase 2 (JNK2) enhances cell migration through epidermal growth factor substrate 8 (EPS8).c-Jun N-terminal Kinase 2 Regulates Multiple Receptor Tyrosine Kinase Pathways in Mouse Mammary Tumor Growth and Metastasis.Paracrine WNT5A Signaling Inhibits Expansion of Tumor-Initiating Cells.Role of JNK in mammary gland development and breast cancer.c-Jun N-terminal kinase 2 prevents luminal cell commitment in normal mammary glands and tumors by inhibiting p53/Notch1 and breast cancer gene 1 expression.In vivo gene manipulation reveals the impact of stress-responsive MAPK pathways on tumor progression.c-Jun N-terminal kinase-mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forksDevelopment of JNK2-selective peptide inhibitors that inhibit breast cancer cell migrationJNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate.Differential regulation of c-Jun protein plays an instrumental role in chemoresistance of cancer cells.Linking JNK Activity to the DNA Damage Response.JNK signaling is needed to tolerate chromosomal instabilityJNK inhibitors as anti-inflammatory and neuroprotective agents.The 2 Faces of JNK Signaling in Cancer.Priming and potentiation of DNA damage response by fibronectin in human colon cancer cells and tumor-derived myofibroblasts.Neddylation controls basal MKK7 kinase activity in breast cancer cells.Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma.IL-17RC is critically required to maintain baseline A20 production to repress JNK isoform-dependent tumor-specific proliferationA c-Jun N-terminal kinase inhibitor, JNK-IN-8, sensitizes triple negative breast cancer cells to lapatinib.Conflicting evidence for the role of JNK as a target in breast cancer cell proliferation: Comparisons between pharmacological inhibition and selective shRNA knockdown approaches.Stress signaling in breast cancer cells induces matrix components that promote chemoresistant metastasis
P2860
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P2860
Jnk2 effects on tumor development, genetic instability and replicative stress in an oncogene-driven mouse mammary tumor model.
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2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Jnk2 effects on tumor developm ...... ven mouse mammary tumor model.
@ast
Jnk2 effects on tumor developm ...... ven mouse mammary tumor model.
@en
Jnk2 effects on tumor developm ...... ven mouse mammary tumor model.
@nl
type
label
Jnk2 effects on tumor developm ...... ven mouse mammary tumor model.
@ast
Jnk2 effects on tumor developm ...... ven mouse mammary tumor model.
@en
Jnk2 effects on tumor developm ...... ven mouse mammary tumor model.
@nl
prefLabel
Jnk2 effects on tumor developm ...... ven mouse mammary tumor model.
@ast
Jnk2 effects on tumor developm ...... ven mouse mammary tumor model.
@en
Jnk2 effects on tumor developm ...... ven mouse mammary tumor model.
@nl
P2093
P2860
P1433
P1476
Jnk2 effects on tumor developm ...... ven mouse mammary tumor model.
@en
P2093
Azadeh Nasrazadani
Carla L Van Den Berg
Jamye F O'Neal
Lynn E Heasley
Michael A Cantrell
Nancy D Ebelt
Peila Chen
Shreya Mitra
Tracy L Vandenbroek
P2860
P304
P356
10.1371/JOURNAL.PONE.0010443
P407
P577
2010-05-03T00:00:00Z