Requirements of Hsp104p activity and Sis1p binding for propagation of the [RNQ(+)] prion
about
Disaggregases, molecular chaperones that resolubilize protein aggregatesThe [RNQ+] prion: a model of both functional and pathological amyloidMyopathy-causing mutations in an HSP40 chaperone disrupt processing of specific client conformers.Analysis of the [RNQ+] prion reveals stability of amyloid fibers as the key determinant of yeast prion variant propagation.Low activity of select Hsp104 mutants is sufficient to propagate unstable prion variantsPrion-like nuclear aggregation of TDP-43 during heat shock is regulated by HSP40/70 chaperones.Extensive diversity of prion strains is defined by differential chaperone interactions and distinct amyloidogenic regions.Regulation of the Hsp104 middle domain activity is critical for yeast prion propagation.Screening for amyloid proteins in the yeast proteome.[PSI(+)] aggregate enlargement in rnq1 nonprion domain mutants, leading to a loss of prion in yeast.
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P2860
Requirements of Hsp104p activity and Sis1p binding for propagation of the [RNQ(+)] prion
description
2009 nî lūn-bûn
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2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Requirements of Hsp104p activity and Sis1p binding for propagation of the [RNQ
@nl
Requirements of Hsp104p activity and Sis1p binding for propagation of the [RNQ(+)] prion
@ast
Requirements of Hsp104p activity and Sis1p binding for propagation of the [RNQ(+)] prion
@en
type
label
Requirements of Hsp104p activity and Sis1p binding for propagation of the [RNQ
@nl
Requirements of Hsp104p activity and Sis1p binding for propagation of the [RNQ(+)] prion
@ast
Requirements of Hsp104p activity and Sis1p binding for propagation of the [RNQ(+)] prion
@en
prefLabel
Requirements of Hsp104p activity and Sis1p binding for propagation of the [RNQ
@nl
Requirements of Hsp104p activity and Sis1p binding for propagation of the [RNQ(+)] prion
@ast
Requirements of Hsp104p activity and Sis1p binding for propagation of the [RNQ(+)] prion
@en
P2093
P2860
P356
P1433
P1476
Requirements of Hsp104p activity and Sis1p binding for propagation of the [RNQ(+)] prion
@en
P2093
Heather L True
J Patrick Bardill
Jennifer E Dulle
Jonathan R Fisher
P2860
P304
P356
10.4161/PRI.3.3.9662
P577
2009-07-30T00:00:00Z