Differential CARM1 expression in prostate and colorectal cancers. - Wikidata - awgldk - TriplyDB

Differential CARM1 expression in prostate and colorectal cancers.

Differential CARM1 expression in prostate and colorectal cancers.

http://www.wikidata.org/entity/Q33576367

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Arginine methyltransferases as novel therapeutic targets for breast cancer The role of testosterone in colorectal carcinoma: pathomechanisms and open questions The role of epigenetics in resistance to Cisplatin chemotherapy in lung cancer PRMT8 demonstrates variant-specific expression in cancer cells and correlates with patient survival in breast, ovarian and gastric cancer.Epigenetics: an emerging player in gastric cancer Global mapping of CARM1 substrates defines enzyme specificity and substrate recognition.Coregulator cell cycle and apoptosis regulator 1 (CCAR1) positively regulates adipocyte differentiation through the glucocorticoid signaling pathway CARM1 is an important determinant of ERα-dependent breast cancer cell differentiation and proliferation in breast cancer cells.A coactivator role of CARM1 in the dysregulation of β-catenin activity in colorectal cancer cell growth and gene expression.Mutations in epigenetic modifiers in myeloid malignancies and the prospect of novel epigenetic-targeted therapy Protein arginine methyltransferase 7 promotes breast cancer cell invasion through the induction of MMP9 expression Differential CARM1 Isoform Expression in Subcellular Compartments and among Malignant and Benign Breast Tumors.Chemical biology of protein arginine modifications in epigenetic regulation Alternatively spliced protein arginine methyltransferase 1 isoform PRMT1v2 promotes the survival and invasiveness of breast cancer cells.A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases.Expression and sub-cellular localization of an epigenetic regulator, co-activator arginine methyltransferase 1 (CARM1), is associated with specific breast cancer subtypes and ethnicity.Overexpression of CARM1 in breast cancer is correlated with poorly characterized clinicopathologic parameters and molecular subtypes.miR-195 enhances the radiosensitivity of colorectal cancer cells by suppressing CARM1.Promises and challenges of anticancer drugs that target the epigenome.Protein arginine methyltransferases (PRMTs) as therapeutic targets.Role of PRMTs in cancer: Could minor isoforms be leaving a mark?Histone modifying enzymes: novel disease biomarkers and assay development.Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response.Identification of the PRMT1v1 and PRMT1v2 specific interactomes by quantitative mass spectrometry in breast cancer cells.Protein arginine methylation/demethylation and cancer.Design and synthesis of selective, small molecule inhibitors of coactivator-associated arginine methyltransferase 1 (CARM1).The Overexpression of CARM1 Promotes Human Osteosarcoma Cell Proliferation through the pGSK3β/β-Catenin/cyclinD1 Signaling Pathway.Transition state mimics are valuable mechanistic probes for structural studies with the arginine methyltransferase CARM1.Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6.Labeling substrates of protein arginine methyltransferase with engineered enzymes and matched S-adenosyl-L-methionine analogues A fast approach to detect gene-gene synergy.CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity.TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma.The prognostic significance of protein arginine methyltransferase 6 expression in colon cancer.Cancer-related transcription regulator protein NAC1 forms a protein complex with CARM1 for ovarian cancer progression.

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Differential CARM1 expression in prostate and colorectal cancers.

http://www.wikidata.org/entity/Q33576367

description

2010 nî lūn-bûn

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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2010 թվականի մայիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Differential CARM1 expression in prostate and colorectal cancers.

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Differential CARM1 expression in prostate and colorectal cancers.

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Differential CARM1 expression in prostate and colorectal cancers.

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type

label

Differential CARM1 expression in prostate and colorectal cancers.

@ast

Differential CARM1 expression in prostate and colorectal cancers.

@en

Differential CARM1 expression in prostate and colorectal cancers.

@nl

prefLabel

Differential CARM1 expression in prostate and colorectal cancers.

@ast

Differential CARM1 expression in prostate and colorectal cancers.

@en

Differential CARM1 expression in prostate and colorectal cancers.

@nl

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Differential CARM1 expression in prostate and colorectal cancers.

@en

P2093

Byung Kook Lee

http://www.w3.org/2001/XMLSchema#string

Chaeyong Jung

http://www.w3.org/2001/XMLSchema#string

Dong Deuk Kwon

http://www.w3.org/2001/XMLSchema#string

Jeong A Bae

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Nguyen Thi Xuan Nguyen

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Ra-Young Park

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Young-Rang Kim

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P2860

Aberrant expression of CARM1, a transcriptional coactivator of androgen receptor, in the development of prostate carcinoma and androgen-independent status

Regulation of transcription by a protein methyltransferase

CBP/p300 in cell growth, transformation, and development

Involvement of arginine methyltransferase CARM1 in androgen receptor function and prostate cancer cell viability

Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53

Arginine methyltransferase CARM1 is a promoter-specific regulator of NF-kappaB-dependent gene expression

Hormone-dependent, CARM1-directed, arginine-specific methylation of histone H3 on a steroid-regulated promoter

Delineation of prognostic biomarkers in prostate cancer

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

Establishing human prostate cancer cell xenografts in bone: induction of osteoblastic reaction by prostate-specific antigen-producing tumors in athymic and SCID/bg mice using LNCaP and lineage-derived metastatic sublines.

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