Activation of Wnt Signaling by Mechanical Loading Is Impaired in the Bone of Old Mice

Activation of Wnt Signaling by Mechanical Loading Is Impaired in the Bone of Old Mice

Item
http://www.wikidata.org/entity/Q33580683
Parathyroid hormone's enhancement of bones' osteogenic response to loading is affected by ageing in a dose- and time-dependent manner.Old age and the associated impairment of bones' adaptation to loading are associated with transcriptomic changes in cellular metabolism, cell-matrix interactions and the cell cycle.Sclerostin's role in bone's adaptive response to mechanical loading.Sost deficiency led to a greater cortical bone formation response to mechanical loading and altered gene expression.Exploiting the WNT Signaling Pathway for Clinical Purposes.Mechanosensitive miRNAs and Bone FormationProlonging disuse in aged mice amplifies cortical but not trabecular bones' response to mechanical loading.Loss of scleraxis in mice leads to geometric and structural changes in cortical bone, as well as asymmetry in fracture healing.IGF-1 signaling mediated cell-specific skeletal mechano-transduction.Evaluation of loading parameters for murine axial tibial loading: Stimulating cortical bone formation while reducing loading duration.Degeneration of the osteocyte network in the C57BL/6 mouse model of aging.Sost deficiency leads to reduced mechanical strains at the tibia midshaft in strain-matched in vivo loading experiments in mice.Transient peak-strain matching partially recovers the age-impaired mechanoadaptive cortical bone response.Role of osteopontin in bone remodeling and orthodontic tooth movement: a review.
P2860

Activation of Wnt Signaling by Mechanical Loading Is Impaired in the Bone of Old Mice

Item
http://www.wikidata.org/entity/Q33580683
description
2016 nî lūn-bûn
@nan
2016 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Activation of Wnt Signaling by Mechanical Loading Is Impaired in the Bone of Old Mice
@ast
Activation of Wnt Signaling by Mechanical Loading Is Impaired in the Bone of Old Mice
@en
Activation of Wnt Signaling by Mechanical Loading Is Impaired in the Bone of Old Mice.
@nl
type
label
Activation of Wnt Signaling by Mechanical Loading Is Impaired in the Bone of Old Mice
@ast
Activation of Wnt Signaling by Mechanical Loading Is Impaired in the Bone of Old Mice
@en
Activation of Wnt Signaling by Mechanical Loading Is Impaired in the Bone of Old Mice.
@nl
prefLabel
Activation of Wnt Signaling by Mechanical Loading Is Impaired in the Bone of Old Mice
@ast
Activation of Wnt Signaling by Mechanical Loading Is Impaired in the Bone of Old Mice
@en
Activation of Wnt Signaling by Mechanical Loading Is Impaired in the Bone of Old Mice.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P932
P356
P1433
P1476
Activation of Wnt Signaling by Mechanical Loading Is Impaired in the Bone of Old Mice
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P932