DNA demethylation in normal colon tissue predicts predisposition to multiple cancers. - Wikidata - awgldk - TriplyDB

DNA demethylation in normal colon tissue predicts predisposition to multiple cancers.

DNA demethylation in normal colon tissue predicts predisposition to multiple cancers.

http://www.wikidata.org/entity/Q33581249

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Multiple primary colorectal cancer: Individual or familial predisposition?The Fine LINE: Methylation Drawing the Cancer Landscape Etiologic field effect: reappraisal of the field effect concept in cancer predisposition and progression Discovery of colorectal cancer PIK3CA mutation as potential predictive biomarker: power and promise of molecular pathological epidemiology Patterns of DNA methylation in the normal colon vary by anatomical location, gender, and age Colorectal advanced neoplasms occur through dual carcinogenesis pathways in individuals with coexisting serrated polyps.DNA methylation alterations of AXIN2 in serrated adenomas and colon carcinomas with microsatellite instability.Field cancerization in the colon: a role for aberrant DNA methylation?Epigenetic Alterations in Colorectal Cancer: Emerging Biomarkers.Epigenetic susceptibility factors for prostate cancer with aging.Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation.Multiple sporadic colorectal cancers display a unique methylation phenotype.Inter-locus as well as intra-locus heterogeneity in LINE-1 promoter methylation in common human cancers suggests selective demethylation pressure at specific CpGs.LINE-1 hypomethylation is neither present in rectal aberrant crypt foci nor associated with field defect in sporadic colorectal neoplasia.Mycoplasma CG- and GATC-specific DNA methyltransferases selectively and efficiently methylate the host genome and alter the epigenetic landscape in human cells.LINE-1 hypomethylation in normal colon mucosa is associated with poor survival in Chinese patients with sporadic colon cancer.Evidence of disrupted high-risk human papillomavirus DNA in morphologically normal cervices of older women.The molecular pathogenesis of colorectal cancer and its potential application to colorectal cancer screening Methylation profiling defines an extensive field defect in histologically normal prostate tissues associated with prostate cancer Tumor size is an independent risk predictor for metachronous colorectal cancer.LINE-1 is preferentially hypomethylated within adenomatous polyps in the presence of synchronous colorectal cancer.Clinical implications of the LINE-1 methylation levels in patients with gastrointestinal cancer.LINE-1 in cancer: multifaceted functions and potential clinical implications.Is DNA methylation the new guardian of the genome?Tumoral LINE-1 hypomethylation is associated with poor survival of patients with intrahepatic cholangiocarcinoma Second German-Catalan workshop on epigenetics & cancer.First Barcelona Conference on Epigenetics and Cancer.German-Catalan workshop on epigenetics and cancer.Non-CpG island promoter hypomethylation and miR-149 regulate the expression of SRPX2 in colorectal cancer.The wayward methyl group and the cascade to cancer.An evolutionary perspective on field cancerization.

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P2860

DNA demethylation in normal colon tissue predicts predisposition to multiple cancers.

http://www.wikidata.org/entity/Q33581249

description

2012 nî lūn-bûn

@nan

2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի փետրվարին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

DNA demethylation in normal colon tissue predicts predisposition to multiple cancers.

@ast

DNA demethylation in normal colon tissue predicts predisposition to multiple cancers.

@en

DNA demethylation in normal colon tissue predicts predisposition to multiple cancers.

@nl

type

label

DNA demethylation in normal colon tissue predicts predisposition to multiple cancers.

@ast

DNA demethylation in normal colon tissue predicts predisposition to multiple cancers.

@en

DNA demethylation in normal colon tissue predicts predisposition to multiple cancers.

@nl

prefLabel

DNA demethylation in normal colon tissue predicts predisposition to multiple cancers.

@ast

DNA demethylation in normal colon tissue predicts predisposition to multiple cancers.

@en

DNA demethylation in normal colon tissue predicts predisposition to multiple cancers.

@nl

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DNA demethylation in normal colon tissue predicts predisposition to multiple cancers.

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F Konishi

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H Kamiyama

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J K Samuelsson

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Y J Kawamura

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Y Miyaki

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P2860

Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

Genetic reconstruction of individual colorectal tumor histories

Analysis of repetitive element DNA methylation by MethyLight.

The history of cancer epigenetics

Induction of tumors in mice by genomic hypomethylation

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

Microsatellite instability in cancer of the proximal colon

LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability

DNA methylation within the normal colorectal mucosa is associated with pathway-specific predisposition to cancer.

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