Neisseria meningitidis Opc invasin binds to the sulphated tyrosines of activated vitronectin to attach to and invade human brain endothelial cells.
about
Pathogens penetrating the central nervous system: infection pathways and the cellular and molecular mechanisms of invasionHost-pathogen interactions in bacterial meningitisHaemophilus influenzae protein E recognizes the C-terminal domain of vitronectin and modulates the membrane attack complexHaemophilus influenzae acquires vitronectin via the ubiquitous Protein F to subvert host innate immunityThe meningococcal vaccine candidate neisserial surface protein A (NspA) binds to factor H and enhances meningococcal resistance to complementTwo strikingly different signaling pathways are induced by meningococcal type IV pili on endothelial and epithelial cellsCell invasion by Neisseria meningitidis requires a functional interplay between the focal adhesion kinase, Src and cortactin.The glycointeractome of serogroup B Neisseria meningitidis strain MC58.Polar invasion and translocation of Neisseria meningitidis and Streptococcus suis in a novel human model of the blood-cerebrospinal fluid barrier.Meningococcal disease and the complement system.Opc expression, LPS immunotype switch and pilin conversion contribute to serum resistance of unencapsulated meningococci.A novel group of Moraxella catarrhalis UspA proteins mediates cellular adhesion via CEACAMs and vitronectin.Meningococcal internalization into human endothelial and epithelial cells is triggered by the influx of extracellular L-glutamate via GltT L-glutamate ABC transporter in Neisseria meningitidisUse of OmpU porins for attachment and invasion of Crassostrea gigas immune cells by the oyster pathogen Vibrio splendidus.Candida albicans uses the surface protein Gpm1 to attach to human endothelial cells and to keratinocytes via the adhesive protein vitronectin.Differential activation of acid sphingomyelinase and ceramide release determines invasiveness of Neisseria meningitidis into brain endothelial cells.Identification and therapeutic potential of a vitronectin binding region of meningococcal msfMultiple Functions of Glutamate Uptake via Meningococcal GltT-GltM L-Glutamate ABC Transporter in Neisseria meningitidis Internalization into Human Brain Microvascular Endothelial CellsYersinia pestis uses the Ail outer membrane protein to recruit vitronectinInhibition of the Membrane Attack Complex by Dengue Virus NS1 through Interaction with Vitronectin and Terminal Complement ProteinsHijacking Complement Regulatory Proteins for Bacterial Immune Evasion.The biology of Neisseria adhesins.The Rickettsia conorii Adr1 Interacts with the C-Terminus of Human Vitronectin in a Salt-Sensitive Manner.Bacteria under stress by complement and coagulation.Role of epidermal growth factor receptor signaling in the interaction of Neisseria meningitidis with endothelial cells.Neisseria meningitidis causes cell cycle arrest of human brain microvascular endothelial cells at S phase via p21 and cyclin G2.Interactions of meningococcal virulence factors with endothelial cells at the human blood-cerebrospinal fluid barrier and their role in pathogenicity.Molecular mechanisms involved in the interaction of Neisseria meningitidis with cells of the human blood-cerebrospinal fluid barrier.Effective plasmid DNA and small interfering RNA delivery to diseased human brain microvascular endothelial cells.Mechanism of invasion of lung epithelial cells by filamentous Legionella pneumophila.A fine-tuned interaction between trimeric autotransporter haemophilus surface fibrils and vitronectin leads to serum resistance and adherence to respiratory epithelial cells.Unraveling Neisseria meningitidis pathogenesis: from functional genomics to experimental models.The sweet side of the pathogenic Neisseria: the role of glycan interactions in colonisation and disease.Moonlighting of Helicobacter pylori catalase protects against complement-mediated killing by utilising the host molecule vitronectin.Complement-activated vitronectin enhances the invasion of nonphagocytic cells by bacterial pathogens Burkholderia and Klebsiella.The mammalian complement system as an epitome of host-pathogen genetic conflicts.Conserved Patterns of Microbial Immune Escape: Pathogenic Microbes of Diverse Origin Target the Human Terminal Complement Inhibitor Vitronectin via a Single Common Motif.Meningococcal surface fibril (Msf) binds to activated vitronectin and inhibits the terminal complement pathway to increase serum resistance.Bioinformatic analysis of meningococcal Msf and Opc to inform vaccine antigen design.Small Rho GTPases and the Effector VipA Mediate the Invasion of Epithelial Cells by Filamentous Legionella pneumophila.
P2860
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P2860
Neisseria meningitidis Opc invasin binds to the sulphated tyrosines of activated vitronectin to attach to and invade human brain endothelial cells.
description
2010 nî lūn-bûn
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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Neisseria meningitidis Opc inv ...... human brain endothelial cells.
@ast
Neisseria meningitidis Opc inv ...... human brain endothelial cells.
@en
Neisseria meningitidis Opc inv ...... human brain endothelial cells.
@nl
type
label
Neisseria meningitidis Opc inv ...... human brain endothelial cells.
@ast
Neisseria meningitidis Opc inv ...... human brain endothelial cells.
@en
Neisseria meningitidis Opc inv ...... human brain endothelial cells.
@nl
prefLabel
Neisseria meningitidis Opc inv ...... human brain endothelial cells.
@ast
Neisseria meningitidis Opc inv ...... human brain endothelial cells.
@en
Neisseria meningitidis Opc inv ...... human brain endothelial cells.
@nl
P2093
P2860
P1433
P1476
Neisseria meningitidis Opc inv ...... human brain endothelial cells.
@en
P2093
Claudia Sa E Cunha
Mumtaz Virji
Natalie J Griffiths
P2860
P304
P356
10.1371/JOURNAL.PPAT.1000911
P577
2010-05-20T00:00:00Z