Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases
about
"Off-Spotter": very fast and exhaustive enumeration of genomic lookalikes for designing CRISPR/Cas guide RNAsCRISPRseek: a bioconductor package to identify target-specific guide RNAs for CRISPR-Cas9 genome-editing systemsGenome Engineering with TALE and CRISPR Systems in NeuroscienceNuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome EditingResources for the design of CRISPR gene editing experimentsHow specific is CRISPR/Cas9 really?Minimizing off-Target Mutagenesis Risks Caused by Programmable NucleasesEnabling functional genomics with genome engineeringDesigned nucleases for targeted genome editingMeasuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9DNA-free two-gene knockout in Chlamydomonas reinhardtii via CRISPR-Cas9 ribonucleoproteinsBiased and Unbiased Methods for the Detection of Off-Target Cleavage by CRISPR/Cas9: An OverviewEngineering T Cells to Functionally Cure HIV-1 InfectionCRISPR/Cas9-induced knockout and knock-in mutations in Chlamydomonas reinhardtiiNLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancerCas9-chromatin binding information enables more accurate CRISPR off-target prediction.Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins.Generation of targeted mutant rice using a CRISPR-Cpf1 systemBLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks.In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuniCRISPR/Cas9-mediated gene knockout screens and target identification via whole-genome sequencing uncover host genes required for picornavirus infection.In vivo genome editing using Staphylococcus aureus Cas9GT-Scan: identifying unique genomic targetsEngineering synthetic TALE and CRISPR/Cas9 transcription factors for regulating gene expressionCRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites.Precision cancer mouse models through genome editing with CRISPR-Cas9.Comparison of TALE designer transcription factors and the CRISPR/dCas9 in regulation of gene expression by targeting enhancersHigh-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.Generation and evaluation of Myostatin knock-out rabbits and goats using CRISPR/Cas9 system.An Efficient Visual Screen for CRISPR/Cas9 Activity in Arabidopsis thaliana.Can genome engineering be used to target cancer-associated enhancers?COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target SitesTarget specificity of the CRISPR-Cas9 system.CRISPR multitargeter: a web tool to find common and unique CRISPR single guide RNA targets in a set of similar sequencessgRNAcas9: a software package for designing CRISPR sgRNA and evaluating potential off-target cleavage sites.Genome editing strategies: potential tools for eradicating HIV-1/AIDS.Targeted mutagenesis in soybean using the CRISPR-Cas9 systemRNA-guided genome editing in Drosophila with the purified Cas9 proteinBoth TALENs and CRISPR/Cas9 directly target the HBB IVS2-654 (C > T) mutation in β-thalassemia-derived iPSCsEgg cell-specific promoter-controlled CRISPR/Cas9 efficiently generates homozygous mutants for multiple target genes in Arabidopsis in a single generation
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Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Cas-OFFinder: a fast and versa ...... Cas9 RNA-guided endonucleases
@ast
Cas-OFFinder: a fast and versa ...... Cas9 RNA-guided endonucleases
@en
type
label
Cas-OFFinder: a fast and versa ...... Cas9 RNA-guided endonucleases
@ast
Cas-OFFinder: a fast and versa ...... Cas9 RNA-guided endonucleases
@en
prefLabel
Cas-OFFinder: a fast and versa ...... Cas9 RNA-guided endonucleases
@ast
Cas-OFFinder: a fast and versa ...... Cas9 RNA-guided endonucleases
@en
P2860
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P356
P1433
P1476
Cas-OFFinder: a fast and versa ...... Cas9 RNA-guided endonucleases
@en
P2860
P304
P356
10.1093/BIOINFORMATICS/BTU048
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P577
2014-01-24T00:00:00Z