Association of obesity risk SNPs in PCSK1 with insulin sensitivity and proinsulin conversion
about
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetesThe association of common variants in PCSK1 with obesity: a HuGE review and meta-analysisContribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individualsFunctional consequences of a novel variant of PCSK1The effect of PCSK1 variants on waist, waist-hip ratio and glucose metabolism is modified by sex and glucose tolerance statusProprotein convertases in high-density lipoprotein metabolism.PCSK1 rs6232 is associated with childhood and adult class III obesity in the Mexican population.Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.Polymorphism rs11085226 in the gene encoding polypyrimidine tract-binding protein 1 negatively affects glucose-stimulated insulin secretion.Modulation of PC1/3 activity by self-interaction and substrate binding.Inhibition of prohormone convertases PC1/3 and PC2 by 2,5-dideoxystreptamine derivatives.Allelic clustering and ancestry-dependent frequencies of rs6232, rs6234, and rs6235 PCSK1 SNPs in a Northern Ontario population sampleGenetic polymorphisms of PCSK2 are associated with glucose homeostasis and progression to type 2 diabetes in a Chinese populationFrequencies of obesity susceptibility alleles among ethnically and racially diverse bariatric patient populations.Genetics of the first seven proprotein convertase enzymes in health and disease.Association of genetic variants of the incretin-related genes with quantitative traits and occurrence of type 2 diabetes in Japanese.Genetic variants in PCSK1 gene are associated with the risk of coronary artery disease in type 2 diabetes in a Chinese Han population: a case control study.Functional and clinical relevance of novel and known PCSK1 variants for childhood obesity and glucose metabolism.PCSK1 Variants and Human Obesity.Hypomethylation of the promoter of the catalytic subunit of protein phosphatase 2A in response to hyperglycemia.High allelic burden of four obesity SNPs is associated with poorer weight loss outcomes following gastric bypass surgery.A genetic variant in the seed region of miR-4513 shows pleiotropic effects on lipid and glucose homeostasis, blood pressure, and coronary artery disease.Effect of a common variant of the PCSK2 gene on reduced insulin secretion.
P2860
Q24635872-AD8AB568-7743-4239-B715-4C104BEE3D2BQ27001166-825492A5-949E-4E5A-AC00-6686C3C389BFQ27003308-C96F96D8-0F51-4507-A218-0ABA778C2675Q28485317-71C1B455-DA3E-402D-A135-3737B9535233Q28740403-0865DA75-0EF3-431F-A0FA-D7A27C994D05Q34256139-57FBBD29-4BC0-4178-BCDE-E7FC6E1BA787Q34318392-52AA3B4F-B11D-46D2-88DE-A3B33E0BC6EAQ34360980-04BE6490-EA6E-485A-A833-9E7AD15D4B1EQ34450307-A43CCB6F-F326-4393-BD09-BE6B2E0DD0B3Q34696850-EE116A9A-E8DE-4CA2-BA96-2DD542D7A0C1Q35776764-86D40E71-3817-4232-86C3-B869C5ECBD15Q36288215-BE1F349D-4A22-451F-AE4B-F741A8176B75Q36320783-B6B64604-11E0-474B-9C53-B333BB9463A2Q36936558-40E250E5-470B-409A-82D7-32ABE93A24F3Q37402594-250BF0C8-28C5-444F-B678-D22DFBDD794BQ37434227-D0218DF0-0423-4D49-B66B-33B7CA683403Q37525540-488C4BF9-FF88-4E43-8E05-0DB44B8A51DDQ37662943-71256B4E-6BC9-44C8-952B-2F3D02BC39D7Q38862134-EB6320C4-1ACB-465D-9A04-1484B733BE25Q38944888-961E2E6B-FFE1-4247-A2E6-DF6CA23A93C9Q47391623-72781B1E-2D6C-4C27-976E-49B650C48428Q51315251-EB5A23B5-7874-45F7-B29C-7AEF97DF2320Q51351064-A64E66E9-7EDC-4109-8C0A-F49F31ECBDF7
P2860
Association of obesity risk SNPs in PCSK1 with insulin sensitivity and proinsulin conversion
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Association of obesity risk SN ...... vity and proinsulin conversion
@ast
Association of obesity risk SN ...... vity and proinsulin conversion
@en
type
label
Association of obesity risk SN ...... vity and proinsulin conversion
@ast
Association of obesity risk SN ...... vity and proinsulin conversion
@en
prefLabel
Association of obesity risk SN ...... vity and proinsulin conversion
@ast
Association of obesity risk SN ...... vity and proinsulin conversion
@en
P2093
P2860
P50
P356
P1433
P1476
Association of obesity risk SN ...... vity and proinsulin conversion
@en
P2093
Andreas Fritsche
Axel Haupt
Caroline Ketterer
Claus Thamer
Fausto Machicao
Silke A Schäfer
P2860
P2888
P356
10.1186/1471-2350-11-86
P577
2010-06-09T00:00:00Z
P5875
P6179
1011192114