Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling - Wikidata - awgldk - TriplyDB

Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling

Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling

http://www.wikidata.org/entity/Q33604076

about

Rab1A is an mTORC1 activator and a colorectal oncogene Advances in Autophagy Regulatory Mechanisms Molecular insights into the premature aging disease progeria Nutrient regulation of the mTOR complex 1 signaling pathway Ste24p Mediates Proteolysis of Both Isoprenylated and Non-prenylated Oligopeptides.Identification of a novel prenyl and palmitoyl modification at the CaaX motif of Cdc42 that regulates RhoGDI binding Expansion of protein farnesyltransferase specificity using "tunable" active site interactions: development of bioengineered prenylation pathways.The late endosome is essential for mTORC1 signaling Optics clustered to output unique solutions: a multi-laser facility for combined single molecule and ensemble microscopy.Recent progress in the study of the Rheb family GTPases.Rheb and Rags come together at the lysosome to activate mTORC1.Direct Interaction between Ras Homolog Enriched in Brain and FK506 Binding Protein 38 in Cashmere Goat Fetal Fibroblast Cells.mTOR direct interactions with Rheb-GTPase and raptor: sub-cellular localization using fluorescence lifetime imaging.Drugging the undruggable RAS: Mission possible?Inhibition of Ras for cancer treatment: the search continues.Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging.Amino acid sensing mechanisms: an Achilles heel in cancer?Recent advances in protein prenyltransferases: substrate identification, regulation, and disease interventions.Rheb GTPase regulates β-secretase levels and amyloid β generation Rheb signaling and tumorigenesis: mTORC1 and new horizons.Farnesylthiosalicylic acid (salirasib) inhibits Rheb in TSC2-null ELT3 cells: a potential treatment for lymphangioleiomyomatosis.A shunt pathway limits the CaaX processing of Hsp40 Ydj1p and regulates Ydj1p-dependent phenotypes.Distinct functional relevance of dynamic GTPase cysteine methylation in fission yeast.Isoprenylcysteine carboxylmethyltransferase function is essential for RAB4A-mediated integrin β3 recycling, cell migration and cancer metastasis Transport to Rhebpress activity.Regulation of mTORC1 complex assembly and signaling by GRp58/ERp57.Effects of RhebL1 silencing on the mTOR pathway.Rheb G-Proteins and the Activation of mTORC1.NMR analysis of the backbone dynamics of the small GTPase Rheb and its interaction with the regulatory protein FKBP38.RHEB1 expression in embryonic and postnatal mouse.Rce1: mechanism and inhibition.RHEB1 insufficiency in aged male mice is associated with stress-induced seizures.Bending the path to TOR.

P2860

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P2860

Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling

http://www.wikidata.org/entity/Q33604076

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

@zh-hk

2009年論文

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2009年論文

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2009年论文

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Differential requirement of CA ...... heb localization and signaling

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Differential requirement of CA ...... heb localization and signaling

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Differential requirement of CA ...... heb localization and signaling

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Differential requirement of CA ...... heb localization and signaling

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Differential requirement of CA ...... heb localization and signaling

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Differential requirement of CA ...... heb localization and signaling

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Differential requirement of CA ...... heb localization and signaling

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A B Hanker

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A D Cox

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C J Der

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E P Henske

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F Tamanoi

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N Mitin

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R S Wilder

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P2860

DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

Co-localization of the TSC2 product tuberin with its target Rap1 in the Golgi apparatus

Multiple sequence elements facilitate Chp Rho GTPase subcellular location, membrane association, and transforming activity

The TSC1-TSC2 complex: a molecular switchboard controlling cell growth

Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding

The genomic landscapes of human breast and colorectal cancers

A novel approach for expression cloning of small GTPases: identification, tissue distribution and chromosome mapping of the human homolog of rheb

Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner

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