PIP3 controls synaptic function by maintaining AMPA receptor clustering at the postsynaptic membrane.
about
Voltage-Controlled Enzymes: The New JanusBifronsThe neuronal K-Cl cotransporter KCC2 influences postsynaptic AMPA receptor content and lateral diffusion in dendritic spinesThe PI3K signaling pathway as a pharmacological target in Autism related disorders and Schizophrenia.Phosphoinositides: tiny lipids with giant impact on cell regulationLateral organization of the postsynaptic densitySubcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disordersFacilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancementPIKE-mediated PI3-kinase activity is required for AMPA receptor surface expressionIntegration of biochemical and electrical signaling-multiscale model of the medium spiny neuron of the striatumPTEN is recruited to the postsynaptic terminal for NMDA receptor-dependent long-term depressionFoxO6 regulates memory consolidation and synaptic functionPKCλ is critical in AMPA receptor phosphorylation and synaptic incorporation during LTPUsing neurolipidomics to identify phospholipid mediators of synaptic (dys)function in Alzheimer's Disease.Constitutive hippocampal cholesterol loss underlies poor cognition in old rodents.Elevated RalA activity in the hippocampus of PI3Kγ knock-out mice lacking NMDAR-dependent long-term depressionStructural basis of PI(4,5)P2-dependent regulation of GluA1 by phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (PIP5K2A)Identification of a novel signaling pathway and its relevance for GluA1 recycling.Seizure-induced reduction in PIP3 levels contributes to seizure-activity and is rescued by valproic acid.Plasma membrane phosphatidylinositol 4,5 bisphosphate is required for internalization of foot-and-mouth disease virus and vesicular stomatitis virus.Activity-dependent PI(3,5)P2 synthesis controls AMPA receptor trafficking during synaptic depression.Inflammation alters trafficking of extrasynaptic AMPA receptors in tonically firing lamina II neurons of the rat spinal dorsal horn.Hyperactivity of newborn Pten knock-out neurons results from increased excitatory synaptic driveSignalling pathways underlying structural plasticity of dendritic spines.Synaptic activity regulates AMPA receptor trafficking through different recycling pathways.Neurogranin regulates CaM dynamics at dendritic spines.Phosphoinositide control of membrane protein function: a frontier led by studies on ion channels.Finding a druggable target for schizophreniaNanoscale Landscape of Phosphoinositides Revealed by Specific Pleckstrin Homology (PH) Domains Using Single-molecule Superresolution Imaging in the Plasma Membrane.Development of inflammation-induced hyperalgesia and allodynia is associated with the upregulation of extrasynaptic AMPA receptors in tonically firing lamina II dorsal horn neurons.Drosophila neuroligin 1 regulates synaptic growth and function in response to activity and phosphoinositide-3-kinase.Role of phosphoinositides at the neuronal synapse.PKCα is required for inflammation-induced trafficking of extrasynaptic AMPA receptors in tonically firing lamina II dorsal horn neurons during the maintenance of persistent inflammatory painSubsynaptic AMPA receptor distribution is acutely regulated by actin-driven reorganization of the postsynaptic density.Protein Crowding within the Postsynaptic Density Can Impede the Escape of Membrane Proteins.The early stage formation of PI3K-AMPAR GluR2 subunit complex facilitates the long term neuroprotection induced by propofol post-conditioning in rats.PIP₃ regulates spinule formation in dendritic spines during structural long-term potentiation.Learning improvement after PI3K activation correlates with de novo formation of functional small spinesGhrelin triggers the synaptic incorporation of AMPA receptors in the hippocampus.Channelopathies linked to plasma membrane phosphoinositides.Nonenzymatic domains of Kalirin7 contribute to spine morphogenesis through interactions with phosphoinositides and Abl
P2860
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P2860
PIP3 controls synaptic function by maintaining AMPA receptor clustering at the postsynaptic membrane.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
PIP3 controls synaptic functio ...... at the postsynaptic membrane.
@ast
PIP3 controls synaptic functio ...... at the postsynaptic membrane.
@en
type
label
PIP3 controls synaptic functio ...... at the postsynaptic membrane.
@ast
PIP3 controls synaptic functio ...... at the postsynaptic membrane.
@en
prefLabel
PIP3 controls synaptic functio ...... at the postsynaptic membrane.
@ast
PIP3 controls synaptic functio ...... at the postsynaptic membrane.
@en
P2093
P2860
P356
P1433
P1476
PIP3 controls synaptic functio ...... g at the postsynaptic membrane
@en
P2093
Cortney N Petrok
Jeffrey R Martens
José A Esteban
Kristin L Arendt
María Royo
Mónica Fernández-Monreal
P2860
P2888
P356
10.1038/NN.2462
P407
P50
P577
2009-12-13T00:00:00Z