Molecular cloning of CD44R1 and CD44R2, two novel isoforms of the human CD44 lymphocyte "homing" receptor expressed by hemopoietic cells
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CD44 cell adhesion moleculesMolecular isoforms of murine CD44 and evidence that the membrane proximal domain is not critical for hyaluronate recognitionAnti-tumor effect against human cancer xenografts by a fully human monoclonal antibody to a variant 8-epitope of CD44R1 expressed on cancer stem cellsOsteopontin and the C-terminal peptide of thrombospondin-4 compete for CD44 binding and have opposite effects on CD133+ cell colony formation.CD44 and adhesion of normal and leukemic CD34+ cells to bone marrow stroma.Prognostic significance of CD44 expression in adenocarcinoma of the lung.Identification and characterization of CD44RC, a novel alternatively spliced soluble CD44 isoform that can potentiate the hyaluronan binding activity of cell surface CD44.Production and characterization of a peptide-based monoclonal antibody against CD44 variant 6.A distinct glycoform of CD44 is an L-selectin ligand on human hematopoietic cellsCytokine regulation of human lung fibroblast hyaluronan (hyaluronic acid) production. Evidence for cytokine-regulated hyaluronan (hyaluronic acid) degradation and human lung fibroblast-derived hyaluronidase.The cytoplasmic tail of CD44 is required for basolateral localization in epithelial MDCK cells but does not mediate association with the detergent-insoluble cytoskeleton of fibroblasts.Regulation of CD44 binding to hyaluronan by glycosylation of variably spliced exons.CD44 and hyaluronan-dependent rolling interactions of lymphocytes on tonsillar stroma.Activated human lymphocytes and aggressive non-Hodgkin's lymphomas express a homologue of the rat metastasis-associated variant of CD44Recent advances in the growth and isolation of primitive human haemopoietic progenitor cells.A monoclonal antibody that blocks poliovirus attachment recognizes the lymphocyte homing receptor CD44Non-invasive detection of malignancy by identification of unusual CD44 gene activity in exfoliated cancer cells.Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons.Hyaluronic acid capsule modulates M protein-mediated adherence and acts as a ligand for attachment of group A Streptococcus to CD44 on human keratinocytes.Two different functions for CD44 proteins in human myelopoiesisSplicing choice from ten variant exons establishes CD44 variability.Identification of sequence motifs responsible for the adhesive interaction between exon v10-containing CD44 isoforms.Significance of E-cadherin and CD44 expression in patients with unresectable metastatic colorectal cancerMolecular pathobiology and immunology of malignant mesothelioma.CD44 isoforms containing exons V6 and V7 are differentially expressed on mitogenically stimulated normal and Epstein-Barr virus-transformed human B cells.Expression and modulation of CD44 variant isoforms in humans.Phosphorylation of CD44 in vivo requires both Ser323 and Ser325, but does not regulate membrane localization or cytoskeletal interaction in epithelial cells.Prevention of tumor metastasis formation by anti-variant CD44.Tumor necrosis factor-alpha induces functionally active hyaluronan-adhesive CD44 by activating sialidase through p38 mitogen-activated protein kinase in lipopolysaccharide-stimulated human monocytic cells.Alternative splicing as a novel of means of regulating the expression of therapeutic genes.Molecular mechanisms regulating the tumor-targeting potential of splice-activated gene expression.Anti-CD44 monoclonal antibody inhibits heart transplant rejection mediated by alloantigen-primed CD4(+) memory T cells in nude mice.Heparan Sulfate-modified CD44 Promotes Hepatocyte Growth Factor/Scatter Factor-induced Signal Transduction through the Receptor Tyrosine Kinase c-Met
P2860
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P2860
Molecular cloning of CD44R1 and CD44R2, two novel isoforms of the human CD44 lymphocyte "homing" receptor expressed by hemopoietic cells
description
1991 nî lūn-bûn
@nan
1991 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Molecular cloning of CD44R1 an ...... expressed by hemopoietic cells
@ast
Molecular cloning of CD44R1 an ...... expressed by hemopoietic cells
@en
type
label
Molecular cloning of CD44R1 an ...... expressed by hemopoietic cells
@ast
Molecular cloning of CD44R1 an ...... expressed by hemopoietic cells
@en
prefLabel
Molecular cloning of CD44R1 an ...... expressed by hemopoietic cells
@ast
Molecular cloning of CD44R1 an ...... expressed by hemopoietic cells
@en
P2093
P2860
P356
P1476
Molecular cloning of CD44R1 an ...... expressed by hemopoietic cells
@en
P2093
Dougherty GJ
Humphries RK
Landorp PM
P2860
P356
10.1084/JEM.174.1.1
P407
P577
1991-07-01T00:00:00Z