Metformin induces an intracellular reductive state that protects oesophageal squamous cell carcinoma cells against cisplatin but not copper-bis(thiosemicarbazones).
about
Metabolic interrogation as a tool to optimize chemotherapeutic regimens.Evaluation of hypoxia with copper-labeled diacetyl-bis(N-methylthiosemicarbazone).Disulfiram/copper-disulfiram Damages Multiple Protein Degradation and Turnover Pathways and Cytotoxicity is Enhanced by Metformin in Oesophageal Squamous Cell Carcinoma Cell Lines.Metformin sensitizes the response of oral squamous cell carcinoma to cisplatin treatment through inhibition of NF-κB/HIF-1α signal axis.Metformin suppressed the proliferation of LoVo cells and induced a time-dependent metabolic and transcriptional alteration.Metformin Synergistically Enhances Cisplatin-Induced Cytotoxicity in Esophageal Squamous Cancer Cells under Glucose-Deprivation ConditionsRedox-dependent modulation of metformin contributes to enhanced sensitivity of esophageal squamous cell carcinoma to cisplatin.Metformin-induced alterations in nucleotide metabolism cause 5-fluorouracil resistance but gemcitabine susceptibility in oesophageal squamous cell carcinoma.
P2860
Q33566853-C388825E-6D14-4D34-8056-68C0C716A101Q35116540-83180244-D998-44B8-93C0-AAC2EE96D6C1Q35595695-ECD586F8-4AE8-4385-B416-41AF541EA792Q37352852-E87E9C8E-3202-4B53-B8E1-2CB9B12FD084Q38816034-123DF44D-D3C7-4A56-9ED3-F7967E7BE529Q41963534-181B8473-E71B-4D7E-9DC9-F9B4F64BD587Q42365321-23FB49E8-F401-4121-A86E-7A093609BA3DQ48103938-3BD6AF14-2E29-4FF5-89CD-AEA8158DF1E0
P2860
Metformin induces an intracellular reductive state that protects oesophageal squamous cell carcinoma cells against cisplatin but not copper-bis(thiosemicarbazones).
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2014 nî lūn-bûn
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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2014 թվականի մայիսին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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name
Metformin induces an intracell ...... opper-bis(thiosemicarbazones).
@ast
Metformin induces an intracell ...... opper-bis(thiosemicarbazones).
@en
type
label
Metformin induces an intracell ...... opper-bis(thiosemicarbazones).
@ast
Metformin induces an intracell ...... opper-bis(thiosemicarbazones).
@en
prefLabel
Metformin induces an intracell ...... opper-bis(thiosemicarbazones).
@ast
Metformin induces an intracell ...... opper-bis(thiosemicarbazones).
@en
P2093
P2860
P356
P1433
P1476
Metformin induces an intracell ...... opper-bis(thiosemicarbazones).
@en
P2093
Amanda Louise Rousseau
Leonard Howard Damelin
Robin Bruce Veale
Rupal Jivan
P2860
P2888
P356
10.1186/1471-2407-14-314
P407
P577
2014-05-05T00:00:00Z
P5875
P6179
1044118538