Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid
about
MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinaseCrystal structure of a calcium-phospholipid binding domain from cytosolic phospholipase A2PLIP, a novel splice variant of Tip60, interacts with group IV cytosolic phospholipase A(2), induces apoptosis, and potentiates prostaglandin productionCharacterization of the promoter for the human 85 kDa cytosolic phospholipase A2 geneInterferon-alpha-induced phosphorylation and activation of cytosolic phospholipase A2 is required for the formation of interferon-stimulated gene factor threeIdentification of a 27 bp 5'-flanking region element responsible for the low level constitutive expression of the human cytosolic phospholipase A2 genep38alpha isoform Mxi2 binds to extracellular signal-regulated kinase 1 and 2 mitogen-activated protein kinase and regulates its nuclear activity by sustaining its phosphorylation levelsInhibition of the MEK1/ERK pathway reduces arachidonic acid release independently of cPLA2 phosphorylation and translocation.Cell-specific expression of group X and group V secretory phospholipases A(2) in human lung airway epithelial cellsCorticosteroids in acute respiratory failureGroup V phospholipase A2 induces leukotriene biosynthesis in human neutrophils through the activation of group IVA phospholipase A2P11, a unique member of the S100 family of calcium-binding proteins, interacts with and inhibits the activity of the 85-kDa cytosolic phospholipase A2Negative regulation of cytosolic phospholipase A(2) by melatonin in the rat pineal glandVascular endothelial growth factor-induced prostacyclin production is mediated by a protein kinase C (PKC)-dependent activation of extracellular signal-regulated protein kinases 1 and 2 involving PKC-delta and by mobilization of intracellular Ca2+LRP1 controls cPLA2 phosphorylation, ABCA1 expression and cellular cholesterol exportAnti-inflammatory and antinociceptive activities of Solenostemon monostachyus aerial part extract in miceA decrease in remodeling accounts for the accumulation of arachidonic acid in murine mast cells undergoing apoptosis.Localization and function of cytosolic phospholipase A2alpha at the Golgi.Membrane lipid interactions in intestinal ischemia/reperfusion-induced InjurySignal pathways mediating oxytocin stimulation of prostaglandin synthesis in select target cells.Macrophage colony stimulating factor activates phosphatidylcholine hydrolysis by cytoplasmic phospholipase A2.Interferon-gamma induces the synthesis and activation of cytosolic phospholipase A2Interleukin 1 alpha causes rapid activation of cytosolic phospholipase A2 by phosphorylation in rat mesangial cells.Proliferation-dependent changes in release of arachidonic acid from endothelial cells.Inhibition of cytosolic Phospholipase A2 prevents prion peptide-induced neuronal damage and co-localisation with Beta III TubulinListeria monocytogenes, an invasive bacterium, stimulates MAP kinase upon attachment to epithelial cells.Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia.Critical duration of intracellular Ca2+ response required for continuous translocation and activation of cytosolic phospholipase A2.Measurements of phospholipases A2, C, and D (PLA2, PLC, and PLD). In vitro microassays, analysis of enzyme isoforms, and intact-cell assaysTargeting cytosolic phospholipase A2 α in colorectal cancer cells inhibits constitutively activated protein kinase B (AKT) and cell proliferation.Cytoplasmic phospholipase A2 translocates to membrane fraction in human neutrophils activated by stimuli that phosphorylate mitogen-activated protein kinase.Intracellular unesterified arachidonic acid signals apoptosis.Regulation of phospholipase A2 in human leukemia cell lines: its implication for intracellular signaling.Ovariectomy enhances and estrogen replacement inhibits the activity of bone marrow factors that stimulate prostaglandin production in cultured mouse calvariae.Regulation of arachidonic acid, eicosanoid, and phospholipase A2 levels in murine mast cells by recombinant stem cell factorCo-compartmentalization of MAP kinases and cytosolic phospholipase A2 at cytoplasmic arachidonate-rich lipid bodies.Labor and inflammation increase the expression of oxytocin receptor in human amnionHuman immunodeficiency virus type 1 envelope protein does not stimulate either prostaglandin formation or the expression of prostaglandin H synthase in THP-1 human monocytes/macrophages.The adenovirus E3-14.7K protein and the E3-10.4K/14.5K complex of proteins, which independently inhibit tumor necrosis factor (TNF)-induced apoptosis, also independently inhibit TNF-induced release of arachidonic acid.Adenovirus E3-10.4K/14.5K protein complex inhibits tumor necrosis factor-induced translocation of cytosolic phospholipase A2 to membranes.
P2860
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P2860
Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid
description
1992 nî lūn-bûn
@nan
1992 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid
@ast
Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid
@en
type
label
Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid
@ast
Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid
@en
prefLabel
Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid
@ast
Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid
@en
P2093
P2860
P356
P1476
Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid
@en
P2093
P2860
P304
P356
10.1073/PNAS.89.13.6147
P407
P577
1992-07-01T00:00:00Z