Glycogen synthase kinase 3 regulates PAX3-FKHR-mediated cell proliferation in human alveolar rhabdomyosarcoma cells.
about
Glycogen synthase kinase-3β is a pivotal mediator of cancer invasion and resistance to therapyGSK-3 as potential target for therapeutic intervention in cancerStimulation of Wnt/ß-catenin pathway in human CD8+ T lymphocytes from blood and lung tumors leads to a shared young/memory phenotypeEmbryonic signaling pathways and rhabdomyosarcoma: contributions to cancer development and opportunities for therapeutic targetingCarnitine palmitoyltransferase 1A (CPT1A): a transcriptional target of PAX3-FKHR and mediates PAX3-FKHR-dependent motility in alveolar rhabdomyosarcoma cellsCyclin-dependent kinase 4 phosphorylates and positively regulates PAX3-FOXO1 in human alveolar rhabdomyosarcoma cellsIdentification of serines 201 and 209 as sites of Pax3 phosphorylation and the altered phosphorylation status of Pax3-FOXO1 during early myogenic differentiation.Challenging issues in pediatric oncologyInhibiting phosphorylation of the oncogenic PAX3-FOXO1 reduces alveolar rhabdomyosarcoma phenotypes identifying novel therapy optionsChildhood rhabdomyosarcoma: recent advances and prospective views.Pharmaceutical inhibition of glycogen synthetase kinase-3β reduces multiple myeloma-induced bone disease in a novel murine plasmacytoma xenograft modelAKT and PAX3-FKHR cooperation enforces myogenic differentiation blockade in alveolar rhabdomyosarcoma cellCombined application of arsenic trioxide and lithium chloride augments viability reduction and apoptosis induction in human rhabdomyosarcoma cell lines.C-type natriuretic peptide in combination with sildenafil attenuates proliferation of rhabdomyosarcoma cells.Small molecule inhibition of PAX3-FOXO1 through AKT activation suppresses malignant phenotypes of alveolar rhabdomyosarcomaPAX3-FKHR regulates the expression of pleiotrophin to mediate motility in alveolar rhabdomyosarcoma cells.Alveolar rhabdomyosarcoma: morphoproteomics and personalized tumor graft testing further define the biology of PAX3-FKHR(FOXO1) subtype and provide targeted therapeutic options.Efficacy of glycogen synthase kinase-3β targeting against osteosarcoma via activation of β-cateninMolecular diagnostics in soft tissue sarcomas and gastrointestinal stromal tumors.Preclinical testing of the glycogen synthase kinase-3β inhibitor tideglusib for rhabdomyosarcoma.Exosomes derived from embryonal and alveolar rhabdomyosarcoma carry differential miRNA cargo and promote invasion of recipient fibroblasts.Too much AKT turns PAX3-FKHR dead: a prospect of novel therapeutic strategy for alveolar rhabdomyosarcoma.Molecular cloning, characterisation and functional analysis of the duck Forkhead box O3 (FOXO3) gene.HNRNPH1 is required for rhabdomyosarcoma cell growth and survival.
P2860
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P2860
Glycogen synthase kinase 3 regulates PAX3-FKHR-mediated cell proliferation in human alveolar rhabdomyosarcoma cells.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Glycogen synthase kinase 3 reg ...... veolar rhabdomyosarcoma cells.
@ast
Glycogen synthase kinase 3 reg ...... veolar rhabdomyosarcoma cells.
@en
type
label
Glycogen synthase kinase 3 reg ...... veolar rhabdomyosarcoma cells.
@ast
Glycogen synthase kinase 3 reg ...... veolar rhabdomyosarcoma cells.
@en
prefLabel
Glycogen synthase kinase 3 reg ...... veolar rhabdomyosarcoma cells.
@ast
Glycogen synthase kinase 3 reg ...... veolar rhabdomyosarcoma cells.
@en
P2093
P2860
P1476
Glycogen synthase kinase 3 reg ...... veolar rhabdomyosarcoma cells.
@en
P2093
Fu-Yue Zeng
Hanqing Dong
Lingling Liu
Taosheng Chen
P2860
P304
P356
10.1016/J.BBRC.2009.12.017
P407
P577
2009-12-06T00:00:00Z