Monoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling. - Wikidata - awgldk - TriplyDB

Monoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling.

Monoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling.

http://www.wikidata.org/entity/Q33620621

about

High Times for Painful Blues: The Endocannabinoid System in Pain-Depression Comorbidity Therapeutic potential of inhibitors of endocannabinoid degradation for the treatment of stress-related hyperalgesia in an animal model of chronic pain Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase: New Targets for Future Antidepressants Endocannabinoid signalling modulates susceptibility to traumatic stress exposure Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants.Antidepressants and changes in concentration of endocannabinoids and N-acylethanolamines in rat brain structures Metabolomic strategies to map functions of metabolic pathways Chronic stress impairs α1-adrenoceptor-induced endocannabinoid-dependent synaptic plasticity in the dorsal raphe nucleus The endocannabinoid/endovanilloid system and depression.Genetic disruption of 2-arachidonoylglycerol synthesis reveals a key role for endocannabinoid signaling in anxiety modulation.Targeting two-pore domain K(+) channels TREK-1 and TASK-3 for the treatment of depression: a new therapeutic concept.Ribosomal protein S6 kinase 1 signaling in prefrontal cortex controls depressive behavior.Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity.Neurobiological Interactions Between Stress and the Endocannabinoid System.Cytisine, a Partial Agonist of α4β2 Nicotinic Acetylcholine Receptors, Reduced Unpredictable Chronic Mild Stress-Induced Depression-Like Behaviors Monoacylglycerol lipase inhibitors produce pro- or antidepressant responses via hippocampal CA1 GABAergic synapses.Cyclin-dependent kinase 5 in the ventral tegmental area regulates depression-related behaviors.Editorial. New Targets of Medical Treatment in Psychiatric Disorders.New perspectives on the involvement of mTOR in depression as well as in the action of antidepressant drugs.Tau-dependent suppression of adult neurogenesis in the stressed hippocampus.Monoglyceride lipase as a drug target: At the crossroads of arachidonic acid metabolism and endocannabinoid signaling.Integrating Endocannabinoid Signaling and Cannabinoids into the Biology and Treatment of Posttraumatic Stress Disorder.HCN2 channels in the ventral tegmental area regulate behavioral responses to chronic stress.Creatine, Similar to Ketamine, Counteracts Depressive-Like Behavior Induced by Corticosterone via PI3K/Akt/mTOR Pathway.The endocannabinoid system in guarding against fear, anxiety and stress.Cannabinoid Modulation of the Stressed Hippocampus.Monoacylglycerol lipase inhibitors reverse paclitaxel-induced nociceptive behavior and proinflammatory markers in a mouse model of chemotherapy-induced neuropathy.

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P2860

Monoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling.

http://www.wikidata.org/entity/Q33620621

description

2014 nî lūn-bûn

@nan

2014 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հունվարին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Monoacylglycerol lipase inhibi ...... activation of mTOR signaling.

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Monoacylglycerol lipase inhibi ...... activation of mTOR signaling.

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type

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Monoacylglycerol lipase inhibi ...... activation of mTOR signaling.

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Monoacylglycerol lipase inhibi ...... activation of mTOR signaling.

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Monoacylglycerol lipase inhibi ...... activation of mTOR signaling.

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Monoacylglycerol lipase inhibi ...... activation of mTOR signaling.

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Monoacylglycerol lipase inhibi ...... activation of mTOR signaling.

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P2093

Bin Pan

http://www.w3.org/2001/XMLSchema#string

Han-ting Zhang

http://www.w3.org/2001/XMLSchema#string

Jonathan Z Long

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Peng Zhong

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Qing-song Liu

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Wei Wang

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Xiaojie Liu

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Zhen Zhang

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P2860

Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects

Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

mTOR activation is required for the antidepressant effects of mGluR₂/₃ blockade

mTOR signaling: at the crossroads of plasticity, memory and disease

A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol

A second endogenous cannabinoid that modulates long-term potentiation

Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling

Depression: a new animal model sensitive to antidepressant treatments

Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

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1763-1776

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scholarly article

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10.1038/NPP.2014.24

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7

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39

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Benjamin Cravatt III

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2014-01-30T00:00:00Z

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259984661

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