The turn formation at positions 22 and 23 in the 42-mer amyloid beta peptide: the emerging role in the pathogenesis of Alzheimer's disease.
about
Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation.The Alzheimer disease protective mutation A2T modulates kinetic and thermodynamic properties of amyloid-β (Aβ) aggregation.Plasma Aβ and PET PiB binding are inversely related in mild cognitive impairment.Point mutations in Aβ induce polymorphic aggregates at liquid/solid interfaces.Toxicity in rat primary neurons through the cellular oxidative stress induced by the turn formation at positions 22 and 23 of Aβ42.Formation of the 42-mer Amyloid β Radical and the Therapeutic Role of Superoxide Dismutase in Alzheimer's Disease.Conformation-specific antibodies to target amyloid β oligomers and their application to immunotherapy for Alzheimer's disease.A Toxic Conformer of Aβ42 with a Turn at 22-23 is a Novel Therapeutic Target for Alzheimer's DiseaseApple Procyanidins Suppress Amyloid β-Protein Aggregation.E22Δ Mutation in Amyloid β-Protein Promotes β-Sheet Transformation, Radical Production, and Synaptotoxicity, But Not Neurotoxicity.Silymarin attenuated the amyloid β plaque burden and improved behavioral abnormalities in an Alzheimer's disease mouse model.
P2860
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P2860
The turn formation at positions 22 and 23 in the 42-mer amyloid beta peptide: the emerging role in the pathogenesis of Alzheimer's disease.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The turn formation at position ...... enesis of Alzheimer's disease.
@ast
The turn formation at position ...... enesis of Alzheimer's disease.
@en
type
label
The turn formation at position ...... enesis of Alzheimer's disease.
@ast
The turn formation at position ...... enesis of Alzheimer's disease.
@en
prefLabel
The turn formation at position ...... enesis of Alzheimer's disease.
@ast
The turn formation at position ...... enesis of Alzheimer's disease.
@en
P2093
P2860
P1476
The turn formation at position ...... enesis of Alzheimer's disease.
@en
P2093
Kazuma Murakami
Takahiko Shimizu
Takuji Shirasawa
Yuichi Masuda
P2860
P304
P356
10.1111/J.1447-0594.2010.00598.X
P478
10 Suppl 1
P577
2010-07-01T00:00:00Z