Causal reasoning identifies mechanisms of sensitivity for a novel AKT kinase inhibitor, GSK690693.

Causal reasoning identifies mechanisms of sensitivity for a novel AKT kinase inhibitor, GSK690693.

Item
http://www.wikidata.org/entity/Q33626022
Leveraging systems biology approaches in clinical pharmacologyComparative transcriptional network modeling of three PPAR-α/γ co-agonists reveals distinct metabolic gene signatures in primary human hepatocytesReverse causal reasoning: applying qualitative causal knowledge to the interpretation of high-throughput data.GSK690693 delays tumor onset and progression in genetically defined mouse models expressing activated Akt.Construction of a computable cell proliferation network focused on non-diseased lung cells.Assessment of network perturbation amplitudes by applying high-throughput data to causal biological networks.Novel pancreatic endocrine maturation pathways identified by genomic profiling and causal reasoning.Discovery of 14-3-3 protein-protein interaction inhibitors that sensitize multidrug-resistant cancer cells to doxorubicin and the Akt inhibitor GSK690693.Causal analysis approaches in Ingenuity Pathway AnalysisTranscription factor HBP1 is a direct anti-cancer target of transcription factor FOXO1 in invasive oral cancer.AKT signaling pathway activated by HIN-1 methylation in non-small cell lung cancer.Construction of biological networks from unstructured information based on a semi-automated curation workflow.Determination of minimal transcriptional signatures of compounds for target prediction.Genes associated with intestinal permeability in ulcerative colitis: changes in expression following infliximab therapy.Expanding primary cells from mucoepidermoid and other salivary gland neoplasms for genetic and chemosensitivity testing.Systems Biology Approaches for Compound Testing
P2860

Causal reasoning identifies mechanisms of sensitivity for a novel AKT kinase inhibitor, GSK690693.

Item
http://www.wikidata.org/entity/Q33626022
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Causal reasoning identifies me ...... T kinase inhibitor, GSK690693.
@ast
Causal reasoning identifies me ...... T kinase inhibitor, GSK690693.
@en
type
label
Causal reasoning identifies me ...... T kinase inhibitor, GSK690693.
@ast
Causal reasoning identifies me ...... T kinase inhibitor, GSK690693.
@en
prefLabel
Causal reasoning identifies me ...... T kinase inhibitor, GSK690693.
@ast
Causal reasoning identifies me ...... T kinase inhibitor, GSK690693.
@en
P1433
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P2093
P2860
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Causal reasoning identifies me ...... KT kinase inhibitor, GSK690693
@en
P2093
P2860
P2888
P304
P31
P356
P407
P478
P50
P577
P5875
P6179
P698
P932