Hyperleptinemia is required for the development of leptin resistance. - Wikidata - awgldk - TriplyDB

Hyperleptinemia is required for the development of leptin resistance.

Hyperleptinemia is required for the development of leptin resistance.

http://www.wikidata.org/entity/Q33627582

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Metabolic reserve as a determinant of cognitive aging Leptin signaling and leptin resistance Over-expression of leptin receptors in hypothalamic POMC neurons increases susceptibility to diet-induced obesity Leptin revisited: its mechanism of action and potential for treating diabetes.Restoration of Lepr in β cells of Lepr null mice does not prevent hyperinsulinemia and hyperglycemia Effects of chronic leptin infusion on subsequent body weight and composition in mice: Can body weight set point be reset?Melanocortin-3 receptors and metabolic homeostasis.Deficiency of PTP1B Attenuates Hypothalamic Inflammation via Activation of the JAK2-STAT3 Pathway in Microglia.Contrasting effects of leptin on food anticipatory and total locomotor activity.Rhythmic leptin is required for weight gain from circadian desynchronized feeding in the mouse.Obesity and leptin resistance: distinguishing cause from effect.Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance.New pharmacological perspectives for the leptin receptor in the treatment of obesity Leptin deficiency in maltreated children.Role of oxytocin signaling in the regulation of body weight.Identification of a physiological role for leptin in the regulation of ambulatory activity and wheel running in mice Leptin mediates the increase in blood pressure associated with obesity.Leptin and beyond: an odyssey to the central control of body weight Adipokines and proinflammatory cytokines, the key mediators in the pathogenesis of nonalcoholic fatty liver disease.A gut-brain neural circuit controlled by intestinal gluconeogenesis is crucial in metabolic health Intracellular leptin-signaling pathways in hypothalamic neurons: the emerging role of phosphatidylinositol-3 kinase-phosphodiesterase-3B-cAMP pathway In vivo and in vitro evidence that chronic activation of the hexosamine biosynthetic pathway interferes with leptin-dependent STAT3 phosphorylation.Therapeutic impact of leptin on diabetes, diabetic complications, and longevity in insulin-deficient diabetic mice ADIPOQ and IL6 variants are associated with a pro-inflammatory status in obeses with cardiometabolic dysfunction.Increased levels of serum leptin are a risk factor for the recurrence of stage I/II hepatocellular carcinoma after curative treatment.Diet-induced obese mice retain endogenous leptin action.Challenges and opportunities of defining clinical leptin resistance Appetite regulation and weight control: the role of gut hormones.Reanalysis of parabiosis of obesity mutants in the age of leptin.Rice Bran Protein Hydrolysates Improve Insulin Resistance and Decrease Pro-inflammatory Cytokine Gene Expression in Rats Fed a High Carbohydrate-High Fat Diet Effects of leptin replacement alone and with exendin-4 on food intake and weight regain in weight-reduced diet-induced obese rats Leptin and the central nervous system control of glucose metabolism.Catestatin (chromogranin A(352-372)) and novel effects on mobilization of fat from adipose tissue through regulation of adrenergic and leptin signaling.Anti-obesity effect of ethanolic extract from Cosmos caudatus Kunth leaf in lean rats fed a high fat diet.AgRP innervation onto POMC neurons increases with age and is accelerated with chronic high-fat feeding in male mice Onset of leptin resistance shows temporal differences related to dose or pulsed treatment Low glycemic load experimental diet more satiating than high glycemic load diet Reprogramming the body weight set point by a reciprocal interaction of hypothalamic leptin sensitivity and Pomc gene expression reverts extreme obesity Leptin status in adolescence is associated with academic performance in high school: a cross-sectional study in a Chilean birth cohort.Hyperleptinemia, adiposity, and risk of metabolic syndrome in older adults.

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Hyperleptinemia is required for the development of leptin resistance.

http://www.wikidata.org/entity/Q33627582

description

2010 nî lūn-bûn

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Hyperleptinemia is required for the development of leptin resistance.

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Hyperleptinemia is required for the development of leptin resistance.

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type

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Hyperleptinemia is required for the development of leptin resistance.

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Hyperleptinemia is required for the development of leptin resistance.

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Hyperleptinemia is required for the development of leptin resistance.

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Hyperleptinemia is required for the development of leptin resistance.

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JOURNAL.PONE.0011376

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Hyperleptinemia is required for the development of leptin resistance.

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Jeffrey M Friedman

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K Schot Hannan

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Matthew L Greenberg

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P2860

Positional cloning of the mouse obese gene and its human homologue

Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

Leptin therapy in insulin-deficient type I diabetes

Leptin responsiveness restored by amylin agonism in diet-induced obesity: evidence from nonclinical and clinical studies

SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985

Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity

A translational profiling approach for the molecular characterization of CNS cell types

Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

Weight-reducing effects of the plasma protein encoded by the obese gene

Effects of the obese gene product on body weight regulation in ob/ob mice

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Zachary A Knight

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