Removal of phospho-head groups of membrane lipids immobilizes voltage sensors of K+ channels.
about
Molecular evolution, functional variation, and proposed nomenclature of the gene family that includes sphingomyelinase D in sicariid spider venomsInteractions between lipids and voltage sensor paddles detected with tarantula toxinsChanges in membrane sphingolipid composition modulate dynamics and adhesion of integrin nanoclusters.Solution Structure and Phospholipid Interactions of the Isolated Voltage-Sensor Domain from KvAPA shared mechanism for lipid- and beta-subunit-coordinated stabilization of the activated K+ channel voltage sensorActivation of neutral sphingomyelinase is involved in acute hypoxic pulmonary vasoconstrictionMembrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory.Regulation of KCNQ/Kv7 family voltage-gated K+ channels by lipids.Outer membrane phospholipase A in phospholipid bilayers: a model system for concerted computational and experimental investigations of amino acid side chain partitioning into lipid bilayers.Differential lipid dependence of the function of bacterial sodium channelsFrom the gating charge response to pore domain movement: initial motions of Kv1.2 dynamics under physiological voltage changes.Engineering of a genetically encodable fluorescent voltage sensor exploiting fast Ci-VSP voltage-sensing movements.Structure and hydration of membranes embedded with voltage-sensing domains.Electrostatic tuning of cellular excitability.Reduced voltage sensitivity in a K+-channel voltage sensor by electric field remodeling.Targeting voltage sensors in sodium channels with spider toxins.Myelin recovery in multiple sclerosis: the challenge of remyelinationBacterial Sphingomyelinase is a State-Dependent Inhibitor of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR)State-dependent electrostatic interactions of S4 arginines with E1 in S2 during Kv7.1 activationStructure and orientation of a voltage-sensor toxin in lipid membranes.The E92K melanocortin 1 receptor mutant induces cAMP production and arrestin recruitment but not ERK activity indicating biased constitutive signalingIn search of a consensus model of the resting state of a voltage-sensing domainThe contribution of individual subunits to the coupling of the voltage sensor to pore opening in Shaker K channels: effect of ILT mutations in heterotetramers.Counteracting suppression of CFTR and voltage-gated K+ channels by a bacterial pathogenic factor with the natural product tannic acidImportance of lipid-pore loop interface for potassium channel structure and function.Structural interactions between lipids, water and S1-S4 voltage-sensing domainsPosition and motions of the S4 helix during opening of the Shaker potassium channel.Phosphatidic acid modulation of Kv channel voltage sensor function.A shaker K+ channel with a miniature engineered voltage sensor.Membrane insertion of a voltage sensor helixElucidating the molecular basis of action of a classic drug: guanidine compounds as inhibitors of voltage-gated potassium channels.Structural interactions of a voltage sensor toxin with lipid membranes.Intermediate states of the Kv1.2 voltage sensor from atomistic molecular dynamics simulations.Clustering and activity tuning of Kv1 channels in myelinated hippocampal axons.Structural dynamics of the S4 voltage-sensor helix in lipid bilayers lacking phosphate groups.Two distinct effects of PIP2 underlie auxiliary subunit-dependent modulation of Slo1 BK channels.Drosophila QVR/SSS modulates the activation and C-type inactivation kinetics of Shaker K(+) channelsPalmitoylation influences the function and pharmacology of sodium channels.Sphingomyelinase D inhibits store-operated Ca2+ entry in T lymphocytes by suppressing ORAI current.Molecular dynamics simulations of voltage-gated cation channels: insights on voltage-sensor domain function and modulation.
P2860
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P2860
Removal of phospho-head groups of membrane lipids immobilizes voltage sensors of K+ channels.
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Removal of phospho-head groups ...... oltage sensors of K+ channels.
@ast
Removal of phospho-head groups ...... oltage sensors of K+ channels.
@en
type
label
Removal of phospho-head groups ...... oltage sensors of K+ channels.
@ast
Removal of phospho-head groups ...... oltage sensors of K+ channels.
@en
prefLabel
Removal of phospho-head groups ...... oltage sensors of K+ channels.
@ast
Removal of phospho-head groups ...... oltage sensors of K+ channels.
@en
P2093
P2860
P356
P1433
P1476
Removal of phospho-head groups ...... oltage sensors of K+ channels.
@en
P2093
P2860
P2888
P304
P356
10.1038/NATURE06618
P407
P577
2008-02-01T00:00:00Z
P6179
1005008294