Aggressive chronic lymphocytic leukemia with elevated genomic complexity is associated with multiple gene defects in the response to DNA double-strand breaks.
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Targeting ATM-deficient CLL through interference with DNA repair pathwaysClinical implications of the molecular genetics of chronic lymphocytic leukemiaThe biology and clinical significance of acquired genomic copy number aberrations and recurrent gene mutations in chronic lymphocytic leukemiaIntegrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemiaMosaic 13q14 deletions in peripheral leukocytes of non-hematologic cancer cases and healthy controlsReduced expression of the retinoblastoma protein shows that the related signaling pathway is essential for mediating the antineoplastic activity of erufosineATM mutation rather than BIRC3 deletion and/or mutation predicts reduced survival in 11q-deleted chronic lymphocytic leukemia: data from the UK LRF CLL4 trial.The role of ATM mutations and 11q deletions in disease progression in chronic lymphocytic leukemia.Genetic abnormalities in chronic lymphocytic leukemia: where we are and where we goPARP1-driven apoptosis in chronic lymphocytic leukemia.A novel measure of chromosome instability can account for prognostic difference in multiple myeloma.A pathobiological role of the insulin receptor in chronic lymphocytic leukemia.Acquired genomic copy number aberrations and survival in chronic lymphocytic leukemia.Detailed analysis of therapy-driven clonal evolution of TP53 mutations in chronic lymphocytic leukemia.The prognostic significance of various 13q14 deletions in chronic lymphocytic leukemia.ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progressionHigh fluorescence in situ hybridization percentage of deletion 11q in patients with chronic lymphocytic leukemia is an independent predictor of adverse outcomeIncidence and clinical implications of ATM aberrations in chronic lymphocytic leukemia.Longitudinal copy number, whole exome and targeted deep sequencing of 'good risk' IGHV-mutated CLL patients with progressive diseaseATM mutations uniformly lead to ATM dysfunction in chronic lymphocytic leukemia: application of functional test using doxorubicin.Integrative genomic analysis implicates gain of PIK3CA at 3q26 and MYC at 8q24 in chronic lymphocytic leukemiaGenetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndromeGenomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia.Telomere dysfunction and its role in haematological cancer.Genome-wide arrays in routine diagnostics of hematological malignancies.The genomic landscape of chronic lymphocytic leukaemia: biological and clinical implications.The molecular pathogenesis of chronic lymphocytic leukaemia.Genome wide SNP array identified multiple mechanisms of genetic changes in Waldenstrom macroglobulinemia.Multiclonal monoallelic 13q14 interstitial deletion in chronic lymphocytic leukemia.Cytogenetic/mutation profile of chronic lymphocytic leukemia/malignant melanoma collision tumors of the skin.13q deletion anatomy and disease progression in patients with chronic lymphocytic leukemia.CD40L/IL-4-stimulated CLL demonstrates variation in translational regulation of DNA damage response genes including ATM
P2860
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P2860
Aggressive chronic lymphocytic leukemia with elevated genomic complexity is associated with multiple gene defects in the response to DNA double-strand breaks.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Aggressive chronic lymphocytic ...... e to DNA double-strand breaks.
@ast
Aggressive chronic lymphocytic ...... e to DNA double-strand breaks.
@en
type
label
Aggressive chronic lymphocytic ...... e to DNA double-strand breaks.
@ast
Aggressive chronic lymphocytic ...... e to DNA double-strand breaks.
@en
prefLabel
Aggressive chronic lymphocytic ...... e to DNA double-strand breaks.
@ast
Aggressive chronic lymphocytic ...... e to DNA double-strand breaks.
@en
P2093
P2860
P1476
Aggressive chronic lymphocytic ...... se to DNA double-strand breaks
@en
P2093
Ammar Al-Zoubi
Kerby Shedden
Paula Bockenstedt
Peter Ouillette
Sami N Malek
Samuel Fossum
P2860
P304
P356
10.1158/1078-0432.CCR-09-2534
P407
P50
P577
2010-01-19T00:00:00Z