Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation. - Wikidata - awgldk - TriplyDB

Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation.

Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation.

http://www.wikidata.org/entity/Q33641532

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MicroRNA in Metabolic Re-Programming and Their Role in Tumorigenesis Hijacking the Hexosamine Biosynthetic Pathway to Promote EMT-Mediated Neoplastic Phenotypes How, with whom and when: an overview of CD147-mediated regulatory networks influencing matrix metalloproteinase activity Cancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapies Lactate shuttles at a glance: from physiological paradigms to anti-cancer treatments SLC transporters as therapeutic targets: emerging opportunities The altered glucose metabolism in tumor and a tumor acidic microenvironment associated with extracellular matrix metalloproteinase inducer and monocarboxylate transporters Toward precision medicine of breast cancer Reexamining cancer metabolism: Lactate production for carcinogenesis could be the purpose and explanation of the Warburg effect Droplet Microfluidic Platform for the Determination of Single-Cell Lactate Release.Co-expression of CD147 and GLUT-1 indicates radiation resistance and poor prognosis in cervical squamous cell carcinoma.Radiosynthesis and validation of (±)-[18F]-3-fluoro-2-hydroxypropionate ([18F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors Radiation induces senescence and a bystander effect through metabolic alterations Cancer stem cell theory and the warburg effect, two sides of the same coin?MicroRNA-34a Encapsulated in Hyaluronic Acid Nanoparticles Induces Epigenetic Changes with Altered Mitochondrial Bioenergetics and Apoptosis in Non-Small-Cell Lung Cancer Cells.Breast Tissue Metabolism by Magnetic Resonance Spectroscopy.CD147 required for corneal endothelial lactate transport.Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review Molecular radiobiology: the state of the art BI-1 enhances Fas-induced cell death through a Na+/H+-associated mechanism.Cell surface lactate receptor GPR81 is crucial for cancer cell survival.Inhibition of monocarboxylate transporter-1 (MCT1) by AZD3965 enhances radiosensitivity by reducing lactate transport.Catabolism of exogenous lactate reveals it as a legitimate metabolic substrate in breast cancer.Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells.CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors.CD14-expressing cancer cells establish the inflammatory and proliferative tumor microenvironment in bladder cancer Investigational cancer drugs targeting cell metabolism in clinical development.Optimisation of immunofluorescence methods to determine MCT1 and MCT4 expression in circulating tumour cells MCT1 promotes the cisplatin-resistance by antagonizing Fas in epithelial ovarian cancer.Combined evaluation of hexokinase 2 and phosphorylated pyruvate dehydrogenase-E1α in invasive front lesions of colorectal tumors predicts cancer metabolism and patient prognosis.Grape seed extract targets mitochondrial electron transport chain complex III and induces oxidative and metabolic stress leading to cytoprotective autophagy and apoptotic death in human head and neck cancer cells.Real-time measurement of hyperpolarized lactate production and efflux as a biomarker of tumor aggressiveness in an MR compatible 3D cell culture bioreactor.Intermittent high dose proton pump inhibitor enhances the antitumor effects of chemotherapy in metastatic breast cancer Hypoxia-induced carbonic anhydrase IX facilitates lactate flux in human breast cancer cells by non-catalytic function.Proton pump inhibitors for the treatment of cancer in companion animals.Lactate does not activate NF-κB in oxidative tumor cells The study of energy metabolism in bladder cancer cells in co-culture conditions using a microfluidic chip.Prognostic significance of monocarboxylate transporter 4 expression in patients with colorectal cancer.Cancer cell spheroids are a better screen for the photodynamic efficiency of glycosylated photosensitizers.Anticancer agents that counteract tumor glycolysis.

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P2860

Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation.

http://www.wikidata.org/entity/Q33641532

description

2010 nî lūn-bûn

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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2010 թվականի հունվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Tumor metabolism of lactate: t ...... for MCT and CD147 regulation.

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Tumor metabolism of lactate: t ...... for MCT and CD147 regulation.

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Tumor metabolism of lactate: t ...... for MCT and CD147 regulation.

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Tumor metabolism of lactate: t ...... for MCT and CD147 regulation.

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Tumor metabolism of lactate: t ...... for MCT and CD147 regulation.

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Future Oncology

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Tumor metabolism of lactate: t ...... for MCT and CD147 regulation.

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Kelly M Kennedy

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Mark W Dewhirst

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P2860

Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter

The Hallmarks of Cancer

Metabolon disruption: a mechanism that regulates bicarbonate transport

Metabolic activation-related CD147-CD98 complex

CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression

Substrate-induced regulation of the human colonic monocarboxylate transporter, MCT1

Molecular changes in the expression of human colonic nutrient transporters during the transition from normality to malignancy

Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle

Lactate metabolism: a new paradigm for the third millennium

SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers

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10.2217/FON.09.145

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20021214

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2819205

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