Gram-scale synthesis of (+)-spongistatin 1: development of an improved, scalable synthesis of the F-ring subunit, fragment union, and final elaboration
about
Spongipyran Synthetic Studies. Evolution of a Scalable Total Synthesis of (+)-Spongistatin 1Marine natural products: a new wave of drugs?Spirastrellolide Studies. Synthesis of the C(1)-C(25) Southern Hemispheres of Spirastrellolides A and B, Exploiting Anion Relay ChemistryToward a more step-economical and scalable synthesis of spongistatin 1 to facilitate cancer drug development effortsComplex fragment coupling by crotylation: A powerful tool for polyketide natural product synthesisConformation-activity relationships of polyketide natural products.Reversed-Polarity Synthesis of Diaryl Ketones through Palladium-Catalyzed Direct Arylation of 2-Aryl-1,3-dithianes.Stereoselectivities of histidine-catalyzed asymmetric aldol additions and contrasts with proline catalysis: a quantum mechanical analysisLong-range anion relay chemistry (LR-ARC): a validated ARC tacticExploiting pseudo C2-symmetry for an efficient synthesis of the F-ring of the spongistatinsThe medicinal potential of promising marine macrolides with anticancer activity.Natural product synthesis in the age of scalability.Strategies for the construction of tetrahydropyran rings in the synthesis of natural products.Design, synthesis, and biological evaluation of diminutive forms of (+)-spongistatin 1: lessons learned.Synthesis of the phorboxazoles-potent, architecturally novel marine natural products.Design, synthesis, and biological evaluation of EF- and ABEF- analogues of (+)-spongistatin 1Type II Anion Relay Chemistry: Exploiting Bifunctional Weinreb Amide Linchpins for the One-Pot Synthesis of Differentiated 1,3-Diketones, Pyrans, and Spiroketals.Hydroxyl-directed stereoselective diboration of alkenes.Highly convergent synthesis of peluroside A.Synthesis of C-disaccharides through a one-pot alkynol cycloisomerization-reductive deoxygenation.Organic synthesis in the Smith Group: a personal selection of a dozen lessons learned at the University of Pennsylvania.Mechanistic investigation on N → Cα → O relay via non-Brook rearrangement: reaction conditions promote synthesis of furo[3,2-c]pyridinones.Anion Relay Chemistry: Development of an Effective Diastereoselective [3+2] Annulation Tactic Exploiting an Aldol/Brook Rearrangement/Cyclization Cascade.[Search for natural substances with therapeutic activity: George R. Pettit].
P2860
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P2860
Gram-scale synthesis of (+)-spongistatin 1: development of an improved, scalable synthesis of the F-ring subunit, fragment union, and final elaboration
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Gram-scale synthesis of (+)-sp ...... t union, and final elaboration
@ast
Gram-scale synthesis of (+)-sp ...... t union, and final elaboration
@en
type
label
Gram-scale synthesis of (+)-sp ...... t union, and final elaboration
@ast
Gram-scale synthesis of (+)-sp ...... t union, and final elaboration
@en
prefLabel
Gram-scale synthesis of (+)-sp ...... t union, and final elaboration
@ast
Gram-scale synthesis of (+)-sp ...... t union, and final elaboration
@en
P2093
P2860
P356
P1433
P1476
Gram-scale synthesis of (+)-sp ...... t union, and final elaboration
@en
P2093
Amos B Smith
Chris Sfouggatakis
Christina A Risatti
Jeffrey B Sperry
Takashi Tomioka
P2860
P304
P356
10.1021/OL801792K
P407
P577
2008-08-28T00:00:00Z