Phylogenetic analysis of ferlin genes reveals ancient eukaryotic origins. - Wikidata - awgldk - TriplyDB

Phylogenetic analysis of ferlin genes reveals ancient eukaryotic origins.

Phylogenetic analysis of ferlin genes reveals ancient eukaryotic origins.

http://www.wikidata.org/entity/Q33643829

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Alternate splicing of dysferlin C2A confers Ca²⁺-dependent and Ca²⁺-independent binding for membrane repair Ferlins: regulators of vesicle fusion for auditory neurotransmission, receptor trafficking and membrane repair Crystal structures of the human Dysferlin inner DysF domain The Dysferlin Domain-Only Protein, Spo73, Is Required for Prospore Membrane Extension in Saccharomyces cerevisiae Dysferlin mutations and mitochondrial dysfunction Modular dispensability of dysferlin C2 domains reveals rational design for mini-dysferlin molecules.Myoferlin depletion in breast cancer cells promotes mesenchymal to epithelial shape change and stalls invasion Expression of myoferlin in human airway epithelium and its role in cell adhesion and zonula occludens-1 expression.Calpain cleavage within dysferlin exon 40a releases a synaptotagmin-like module for membrane repair.AAV.Dysferlin Overlap Vectors Restore Function in Dysferlinopathy Animal Models Mechanistic modeling of the effects of myoferlin on tumor cell invasion.Membrane Repair: Mechanisms and Pathophysiology.FER-1/Dysferlin promotes cholinergic signaling at the neuromuscular junction in C. elegans and mice Dysferlin is essential for endocytosis in the sea star oocyte.Translational research and therapeutic perspectives in dysferlinopathies.Membrane Injury and Repair in the Muscular Dystrophies.Calcium signaling in membrane repair.Enzymatic cleavage of myoferlin releases a dual C2-domain module linked to ERK signalling.Dysferlin rescue by spliceosome-mediated pre-mRNA trans-splicing targeting introns harbouring weakly defined 3' splice sites.Ferlins Show Tissue-Specific Expression and Segregate as Plasma Membrane/Late Endosomal or Trans-Golgi/Recycling Ferlins.Dysferlin Binds SNAREs (Soluble N-Ethylmaleimide-sensitive Factor (NSF) Attachment Protein Receptors) and Stimulates Membrane Fusion in a Calcium-sensitive Manner.Emerging Functional Differences between the Synaptotagmin and Ferlin Calcium Sensor Families.Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses.Limited proteolysis as a tool to probe the tertiary conformation of dysferlin and structural consequences of patient missense variant L344P.

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Phylogenetic analysis of ferlin genes reveals ancient eukaryotic origins.

http://www.wikidata.org/entity/Q33643829

description

2010 nî lūn-bûn

@nan

2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年学术文章

@wuu

2010年学术文章

@zh-cn

2010年学术文章

@zh-hans

2010年学术文章

@zh-my

2010年学术文章

@zh-sg

2010年學術文章

@yue

name

Phylogenetic analysis of ferlin genes reveals ancient eukaryotic origins.

@ast

Phylogenetic analysis of ferlin genes reveals ancient eukaryotic origins.

@en

type

label

Phylogenetic analysis of ferlin genes reveals ancient eukaryotic origins.

@ast

Phylogenetic analysis of ferlin genes reveals ancient eukaryotic origins.

@en

prefLabel

Phylogenetic analysis of ferlin genes reveals ancient eukaryotic origins.

@ast

Phylogenetic analysis of ferlin genes reveals ancient eukaryotic origins.

@en

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1471-2148-10-231

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BMC Evolutionary Biology

P1476

Phylogenetic analysis of ferlin genes reveals ancient eukaryotic origins

@en

P2093

Angela Lek

http://www.w3.org/2001/XMLSchema#string

Kathryn N North

http://www.w3.org/2001/XMLSchema#string

Monkol Lek

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P2860

Survey sequencing and comparative analysis of the elephant shark (Callorhinchus milii) genome

A mutation in OTOF, encoding otoferlin, a FER-1-like protein, causes DFNB9, a nonsyndromic form of deafness

E-Syts, a family of membranous Ca2+-sensor proteins with multiple C2 domains

Evolutionarily conserved multiple C2 domain proteins with two transmembrane regions (MCTPs) and unusual Ca2+ binding properties

AHNAK, a novel component of the dysferlin protein complex, redistributes to the cytoplasm with dysferlin during skeletal muscle regeneration

MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform

SMART, a simple modular architecture research tool: identification of signaling domains

The Pfam protein families database

The C2 domain calcium-binding motif: structural and functional diversity

Solution structure of the inner DysF domain of myoferlin and implications for limb girdle muscular dystrophy type 2b

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1471-2148-10-231

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10.1186/1471-2148-10-231

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10

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Sandra T Cooper

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ferlin-like protein, putative

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