The 289-amino acid E1A protein of adenovirus binds zinc in a region that is important for trans-activation.
about
Roles for APIS and the 20S proteasome in adenovirus E1A-dependent transcriptionvav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cellsAdenovirus E1A functions as a cofactor for retinoic acid receptor beta (RAR beta) through direct interaction with RAR betaSubregions of the adenovirus E1A transactivation domain target multiple components of the TFIID complexAdenovirus E1A proteins interact with the cellular YY1 transcription factorIdentification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5EBF contains a novel zinc coordination motif and multiple dimerization and transcriptional activation domainsLoss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potentialRole of Zn2+ ions in host-virus interactionsStructural determinants present in the C-terminal binding protein binding site of adenovirus early region 1A proteins.The human papillomavirus type 16 E7 gene product interacts with and trans-activates the AP1 family of transcription factorsEngineering viral vectors to subvert the airway defense response.Sequence-specific DNA binding by glucocorticoid receptor "zinc finger peptides"Replication-defective bovine adenovirus type 3 as an expression vectorA retroviral Cys-Xaa2-Cys-Xaa4-His-Xaa4-Cys peptide binds metal ions: spectroscopic studies and a proposed three-dimensional structureSimian virus 40 small t antigen trans activates the adenovirus E2A promoter by using mechanisms distinct from those used by adenovirus E1A.Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus.The zinc finger region of the adenovirus E1A transactivating domain complexes with the TATA box binding protein.vav: a molecule for all haemopoiesis?Molecular cloning and characterization of a cDNA showing negative regulation in v-src-transformed 3Y1 rat fibroblasts.Activation domain-mediator interactions promote transcription preinitiation complex assembly on promoter DNAAnalysis of a developmentally regulated nuclear localization signal in Xenopus.Formation of the peroxisome lumen is abolished by loss of Pichia pastoris Pas7p, a zinc-binding integral membrane protein of the peroxisome.Human papillomavirus type 18 E7 protein requires intact Cys-X-X-Cys motifs for zinc binding, dimerization, and transformation but not for Rb bindingMutational analysis of a predicted zinc-binding motif in the 26-kilodalton protein encoded by the vaccinia virus A2L gene: correlation of zinc binding with late transcriptional transactivation activity.Transcriptional activation by the adenovirus larger E1a product is mediated by members of the cellular transcription factor ATF family which can directly associate with E1aAdenovirus L-E1A activates transcription through mediator complex-dependent recruitment of the super elongation complexRecombinant human adenoviruses containing hybrid adenovirus type 5 (Ad5)/Ad12 E1A genes: characterization of hybrid E1A proteins and analysis of transforming activity and host range.trans-dominant mutants of E1A provide genetic evidence that the zinc finger of the trans-activating domain binds a transcription factorFusion of adenovirus E1A to the glucocorticoid receptor by high-resolution deletion cloning creates a hormonally inducible viral transactivatorThe second-largest subunit of the poxvirus RNA polymerase is similar to the corresponding subunits of procaryotic and eucaryotic RNA polymerases.Papillomavirus polypeptides E6 and E7 are zinc-binding proteinsAdenovirus early region 3 promoter regulation by E1A/E1B is independent of alterations in DNA binding and gene activation of CREB/ATF and AP1.Limited temperature-sensitive transactivation by mutant adenovirus type 2 E1a proteins.A point mutational analysis of human papillomavirus type 16 E7 protein.Deletion mutants of herpesvirus saimiri define an open reading frame necessary for transformation.Mutational analysis of autonomously functioning trans-activating peptides encoded by adenovirus E1A: evidence for two subdomains.Multiple transcriptional regulatory domains in the human immunodeficiency virus type 1 long terminal repeat are involved in basal and E1A/E1B-induced promoter activity.Intrinsic structural disorder in adenovirus E1A: a viral molecular hub linking multiple diverse processes.Adenovirus E1B 55-kilodalton protein: multiple roles in viral infection and cell transformation.
P2860
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P2860
The 289-amino acid E1A protein of adenovirus binds zinc in a region that is important for trans-activation.
description
1988 nî lūn-bûn
@nan
1988 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
The 289-amino acid E1A protein ...... mportant for trans-activation.
@ast
The 289-amino acid E1A protein ...... mportant for trans-activation.
@en
type
label
The 289-amino acid E1A protein ...... mportant for trans-activation.
@ast
The 289-amino acid E1A protein ...... mportant for trans-activation.
@en
prefLabel
The 289-amino acid E1A protein ...... mportant for trans-activation.
@ast
The 289-amino acid E1A protein ...... mportant for trans-activation.
@en
P2093
P2860
P356
P1476
The 289-amino acid E1A protein ...... mportant for trans-activation.
@en
P2093
D J Friedman
L C Webster
M Rosenberg
R P Ricciardi
P2860
P304
P356
10.1073/PNAS.85.17.6450
P407
P577
1988-09-01T00:00:00Z