Design and synthesis of potent Quillaja saponin vaccine adjuvants - Wikidata - awgldk - TriplyDB

Design and synthesis of potent Quillaja saponin vaccine adjuvants

Design and synthesis of potent Quillaja saponin vaccine adjuvants

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Development of Improved Vaccine Adjuvants Based on the Saponin Natural Product QS-21 through Chemical Synthesis Construction and immunogenicity of a DNA vaccine coexpressing GP3 and GP5 of genotype-I porcine reproductive and respiratory syndrome virus The saponins: polar isoprenoids with important and diverse biological activities.Utility of coupled-HSQC experiments in the intact structural elucidation of three complex saponins from Blighia sapida.Development of a minimal saponin vaccine adjuvant based on QS-21 Design, synthesis, and immunologic evaluation of vaccine adjuvant conjugates based on QS-21 and tucaresol Meta-Analysis on Randomized Controlled Trials of Vaccines with QS-21 or ISCOMATRIX Adjuvant: Safety and Tolerability.Synthesis and preclinical evaluation of QS-21 variants leading to simplified vaccine adjuvants and mechanistic probes Natural and synthetic saponin adjuvant QS-21 for vaccines against cancer.Synthesis of QS-21-based immunoadjuvants.An overview of adjuvant formulations and delivery systems."Pruning of biomolecules and natural products (PBNP)": an innovative paradigm in drug discovery.Carbohydrate-based vaccine adjuvants - discovery and development.Synthetic agonists of NOD-like, RIG-I-like, and C-type lectin receptors for probing the inflammatory immune response.Quillaja Saponin Variants with Central Glycosidic Linkage Modifications Exhibit Distinct Conformations and Adjuvant Activities QS-21 enhances the early antibody response to oil adjuvant foot-and-mouth disease vaccine in cattle.N-Alkyl derivatives of diosgenyl 2-amino-2-deoxy-β-D-glucopyranoside; synthesis and antimicrobial activity.Versatile strategy for the divergent synthesis of linear oligosaccharide domain variants of Quillaja saponin vaccine adjuvants.Chemistry and biology of oligovalent β-(1→2)-linked oligomannosides: new insights into carbohydrate-based adjuvants in immunotherapy.Antigenic extracts of Leishmania braziliensis and Leishmania amazonensis associated with saponin partially protects BALB/c mice against Leishmania chagasi infection by suppressing IL-10 and IL-4 production.Semisynthesis of Analogues of the Saponin Immunoadjuvant QS-21.Rapid assembly of the doubly-branched pentasaccharide domain of the immunoadjuvant jujuboside A via convergent B(C6F5)3-catalyzed glycosylation of sterically-hindered precursors.2-Nitroglycals: Versatile Building Blocks for the Synthesis of 2-Aminoglycosides Stereoselective Access to β-C-Glycosamines by Nitro-Michael Addition of Organolithium Reagents

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Design and synthesis of potent Quillaja saponin vaccine adjuvants

http://www.wikidata.org/entity/Q33645835

description

2010 nî lūn-bûn

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2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Design and synthesis of potent Quillaja saponin vaccine adjuvants

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Design and synthesis of potent Quillaja saponin vaccine adjuvants

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Journal of the American Chemical Society

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Design and synthesis of potent Quillaja saponin vaccine adjuvants

@en

P2093

Annie Won

http://www.w3.org/2001/XMLSchema#string

David Y Gin

http://www.w3.org/2001/XMLSchema#string

Feng Hong

http://www.w3.org/2001/XMLSchema#string

Govind Ragupathi

http://www.w3.org/2001/XMLSchema#string

Michelle M Adams

http://www.w3.org/2001/XMLSchema#string

Nicholas R Perl

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Payal Damani

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Philip O Livingston

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Safety and immunogenicity of RTS,S/AS02D malaria vaccine in infants

GlaxoSmithKline Adjuvant Systems in vaccines: concepts, achievements and perspectives.

Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: a phase I trial

Synthetic vaccines: the role of adjuvants in immune targeting.

Vaccine adjuvants: role and mechanisms of action in vaccine immunogenicity.

The safety and tolerability of an HIV-1 DNA prime-protein boost vaccine (DP6-001) in healthy adult volunteers

The science of adjuvants.

ISCOMATRIX adjuvant for prophylactic and therapeutic vaccines.

Synthesis of QS-21-xylose: establishment of the immunopotentiating activity of synthetic QS-21 adjuvant with a melanoma vaccine.

Divergent immunoglobulin g subclass activity through selective Fc receptor binding.

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20088518

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