Jaagsiekte retrovirus is widely distributed both in T and B lymphocytes and in mononuclear phagocytes of sheep with naturally and experimentally acquired pulmonary adenomatosis.
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Experimental transmission of enzootic nasal adenocarcinoma in sheep.Jaagsiekte sheep retrovirus is necessary and sufficient to induce a contagious lung cancer in sheepRetrovirus vectors bearing jaagsiekte sheep retrovirus Env transduce human cells by using a new receptor localized to chromosome 3p21.3.Jaagsiekte sheep retrovirus proviral clone JSRV(JS7), derived from the JS7 lung tumor cell line, induces ovine pulmonary carcinoma and is integrated into the surfactant protein A geneLung adenocarcinoma originates from retrovirus infection of proliferating type 2 pneumocytes during pulmonary post-natal development or tissue repairIn vivo and in vitro analysis of factor binding sites in Jaagsiekte sheep retrovirus long terminal repeat enhancer sequences: roles of HNF-3, NF-I, and C/EBP for activity in lung epithelial cells.Mechanism of cell entry and transformation by enzootic nasal tumor virus.Transformation of rodent fibroblasts by the jaagsiekte sheep retrovirus envelope is receptor independent and does not require the surface domain.Jaagsiekte sheep retrovirus infection of lung slice cultures.Lung cancer induced in mice by the envelope protein of jaagsiekte sheep retrovirus (JSRV) closely resembles lung cancer in sheep infected with JSRVDiagnosis and prevalence of ovine pulmonary adenocarcinoma in lung tissues of naturally infected farm sheep.Host species barriers to Jaagsiekte sheep retrovirus replication and carcinogenesis.The long terminal repeat of Jaagsiekte sheep retrovirus is preferentially active in differentiated epithelial cells of the lungs.In vitro infection of ovine cell lines by Jaagsiekte sheep retrovirus.A phosphatidylinositol 3-kinase docking site in the cytoplasmic tail of the Jaagsiekte sheep retrovirus transmembrane protein is essential for envelope-induced transformation of NIH 3T3 cells.In vivo tumorigenesis by Jaagsiekte sheep retrovirus (JSRV) requires Y590 in Env TM, but not full-length orfX open reading frame.Cells infected with Jaagsiekte sheep retrovirus are detected in the bone marrow of asymptomatic sheepSpecific in vivo expression in type II pneumocytes of the Jaagsiekte sheep retrovirus long terminal repeat in transgenic mice.First confirmation by PCR of Jaagsiekte sheep retrovirus in Ireland and prevalence of ovine pulmonary adenocarcinoma in adult sheep at slaughter.
P2860
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P2860
Jaagsiekte retrovirus is widely distributed both in T and B lymphocytes and in mononuclear phagocytes of sheep with naturally and experimentally acquired pulmonary adenomatosis.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Jaagsiekte retrovirus is widel ...... quired pulmonary adenomatosis.
@ast
Jaagsiekte retrovirus is widel ...... quired pulmonary adenomatosis.
@en
type
label
Jaagsiekte retrovirus is widel ...... quired pulmonary adenomatosis.
@ast
Jaagsiekte retrovirus is widel ...... quired pulmonary adenomatosis.
@en
prefLabel
Jaagsiekte retrovirus is widel ...... quired pulmonary adenomatosis.
@ast
Jaagsiekte retrovirus is widel ...... quired pulmonary adenomatosis.
@en
P2093
P2860
P1433
P1476
Jaagsiekte retrovirus is widel ...... quired pulmonary adenomatosis.
@en
P2093
I McKendrick
L Gonzalez
M Garcia-Goti
M J Holland
M de las Heras
P2860
P304
P577
1999-05-01T00:00:00Z