Distinct prion strains are defined by amyloid core structure and chaperone binding site dynamics.
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Prion strains and amyloid polymorphism influence phenotypic variationPrion-like polymerization as a signaling mechanismYeast prions: structure, biology, and prion-handling systemsStructure-based view on [PSI(+)] prion propertiesProgress towards structural understanding of infectious sheep PrP-amyloid.Specific chaperones and regulatory domains in control of amyloid formation.Sensitivity-enhanced NMR reveals alterations in protein structure by cellular milieusCombining DNP NMR with segmental and specific labeling to study a yeast prion protein strain that is not parallel in-register.Heat shock protein 104 (Hsp104)-mediated curing of [PSI+] yeast prions depends on both [PSI+] conformation and the properties of the Hsp104 homologs.Prion propagation can occur in a prokaryote and requires the ClpB chaperone.Locating folds of the in-register parallel β-sheet of the Sup35p prion domain infectious amyloid.Physical and structural basis for polymorphism in amyloid fibrilsOrientation of aromatic residues in amyloid cores: structural insights into prion fiber diversityFunctional diversification of hsp40: distinct j-protein functional requirements for two prions allow for chaperone-dependent prion selectionAmyloid polymorphism: structural basis and neurobiological relevance.The 26S Proteasome Degrades the Soluble but Not the Fibrillar Form of the Yeast Prion Ure2p In Vitro.Hsp40 function in yeast prion propagation: Amyloid diversity necessitates chaperone functional complexity.The Structure and Dynamics of Higher-Order Assemblies: Amyloids, Signalosomes, and Granules.DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins.Extensive diversity of prion strains is defined by differential chaperone interactions and distinct amyloidogenic regions.The life of [PSI].Engineered bacterial hydrophobic oligopeptide repeats in a synthetic yeast prion, [REP-PSI (+)].Polymorphism of amyloid fibrils formed by a peptide from the yeast prion protein Sup35: AFM and Tip-Enhanced Raman Scattering studiesRepA-WH1 prionoid: Clues from bacteria on factors governing phase transitions in amyloidogenesis.Aggregation interplay between variants of the RepA-WH1 prionoid in Escherichia coli.Human TorsinA can function in the yeast cytosol as a molecular chaperone.Insights into protein misfolding and aggregation enabled by solid-state NMR spectroscopy.Signaling-Related Mobility Changes in Bacterial Chemotaxis Receptors Revealed by Solid-State NMR.Over-expression of the molecular chaperone Hsp104 in Saccharomyces cerevisiae results in the malpartition of [PSI+ ] propagons.Variant-specific and reciprocal Hsp40 functions in Hsp104-mediated prion elimination.Amyloid fibrils embodying distinctive yeast prion phenotypes exhibit diverse morphologies.
P2860
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P2860
Distinct prion strains are defined by amyloid core structure and chaperone binding site dynamics.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Distinct prion strains are def ...... aperone binding site dynamics.
@ast
Distinct prion strains are def ...... aperone binding site dynamics.
@en
type
label
Distinct prion strains are def ...... aperone binding site dynamics.
@ast
Distinct prion strains are def ...... aperone binding site dynamics.
@en
prefLabel
Distinct prion strains are def ...... aperone binding site dynamics.
@ast
Distinct prion strains are def ...... aperone binding site dynamics.
@en
P2093
P2860
P1476
Distinct prion strains are def ...... haperone binding site dynamics
@en
P2093
Angela C Jacavone
Galia T Debelouchina
Robert G Griffin
Susan Lindquist
Tea Dorminy
P2860
P304
P356
10.1016/J.CHEMBIOL.2013.12.013
P577
2014-01-30T00:00:00Z