Antibody-independent protection against rotavirus infection of mice stimulated by intranasal immunization with chimeric VP4 or VP6 protein.
about
Llama-derived single-chain antibody fragments directed to rotavirus VP6 protein possess broad neutralizing activity in vitro and confer protection against diarrhea in mice.Intranasal administration of 2/6-rotavirus-like particles with mutant Escherichia coli heat-labile toxin (LT-R192G) induces antibody-secreting cell responses but not protective immunity in gnotobiotic pigs.Oral Administration of a Seed-based Bivalent Rotavirus Vaccine Containing VP6 and NSP4 Induces Specific Immune Responses in MiceFunctional mapping of protective domains and epitopes in the rotavirus VP6 protein.Protection against aerosolized Yersinia pestis challenge following homologous and heterologous prime-boost with recombinant plague antigens.Development of a Bacillus subtilis-based rotavirus vaccineImmune responses elicited against rotavirus middle layer protein VP6 inhibit viral replication in vitro and in vivo.Mice develop effective but delayed protective immune responses when immunized as neonates either intranasally with nonliving VP6/LT(R192G) or orally with live rhesus rotavirus vaccine candidatesImmune mediators of rotavirus antigenemia clearance in mice.Inhibitory effects of bile acids and synthetic farnesoid X receptor agonists on rotavirus replication.Magnitude of serum and intestinal antibody responses induced by sequential replicating and nonreplicating rotavirus vaccines in gnotobiotic pigs and correlation with protectionWhy does the world need another rotavirus vaccine?Prevention of the murine model of biliary atresia after live rotavirus vaccination of dams.Comparative immunogenicity in mice of rotavirus VP6 tubular structures and virus-like particles.Rotavirus Recombinant VP6 Nanotubes Act as an Immunomodulator and Delivery Vehicle for Norovirus Virus-Like ParticlesRotavirus anti-VP6 secretory immunoglobulin A contributes to protection via intracellular neutralization but not via immune exclusion.Protection of the villus epithelial cells of the small intestine from rotavirus infection does not require immunoglobulin A.CD4 T cells are the only lymphocytes needed to protect mice against rotavirus shedding after intranasal immunization with a chimeric VP6 protein and the adjuvant LT(R192G).Rhesus rotavirus VP6 regulates ERK-dependent calcium influx in cholangiocytes.Differential requirements for T cells in viruslike particle- and rotavirus-induced protective immunity.Association of gamma interferon and interleukin-17 production in intestinal CD4+ T cells with protection against rotavirus shedding in mice intranasally immunized with VP6 and the adjuvant LT(R192G).Antigenicity and immunogenicity of rotavirus VP6 protein expressed on the surface of Lactococcus lactis.The Nontoxic Cholera B Subunit Is a Potent Adjuvant for Intradermal DC-Targeted VaccinationRotavirus VP6 protein mucosally delivered by cell wall-derived particles from Lactococcus lactis induces protection against infection in a murine model
P2860
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P2860
Antibody-independent protection against rotavirus infection of mice stimulated by intranasal immunization with chimeric VP4 or VP6 protein.
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Antibody-independent protectio ...... h chimeric VP4 or VP6 protein.
@ast
Antibody-independent protectio ...... h chimeric VP4 or VP6 protein.
@en
type
label
Antibody-independent protectio ...... h chimeric VP4 or VP6 protein.
@ast
Antibody-independent protectio ...... h chimeric VP4 or VP6 protein.
@en
prefLabel
Antibody-independent protectio ...... h chimeric VP4 or VP6 protein.
@ast
Antibody-independent protectio ...... h chimeric VP4 or VP6 protein.
@en
P2093
P2860
P1433
P1476
Antibody-independent protectio ...... th chimeric VP4 or VP6 protein
@en
P2093
P2860
P304
P577
1999-09-01T00:00:00Z