The interactions of adenylate cyclases with P-site inhibitors.
about
Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonateMolecular details of cAMP generation in mammalian cells: a tale of two systemsRegulation of type V adenylate cyclase by Ric8a, a guanine nucleotide exchange factorCardiac cAMP: production, hydrolysis, modulation and detectionBacillus anthracis edema factor substrate specificity: evidence for new modes of actionSimilarly potent inhibition of adenylyl cyclase by P-site inhibitors in hearts from wild type and AC5 knockout miceCrystal Structure and Regulation Mechanisms of the CyaB Adenylyl Cyclase from the Human Pathogen Pseudomonas aeruginosaCharacterization of phylogenetically distant members of the adenylate cyclase family from mycobacteria: Rv1647 from Mycobacterium tuberculosis and its orthologue ML1399 from M. lepraeStructure-based development of novel adenylyl cyclase inhibitorsCompartmentalized autocrine signaling to cystic fibrosis transmembrane conductance regulator at the apical membrane of airway epithelial cellsStructural and kinetic analyses of the interaction of anthrax adenylyl cyclase toxin with reaction products cAMP and pyrophosphate.PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis.Isoform selectivity of adenylyl cyclase inhibitors: characterization of known and novel compoundsGuanylyl cyclase is an ATP sensor coupling nitric oxide signaling to cell metabolism.Guanylyl cyclases A and B are asymmetric dimers that are allosterically activated by ATP binding to the catalytic domain.Inhibitors of membranous adenylyl cyclases.Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers.Identification of a selective small-molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties.Mycobacterial adenylyl cyclases: biochemical diversity and structural plasticity.A new site and mechanism of action for the widely used adenylate cyclase inhibitor SQ22,536Correlation between Activity and Domain Complementation in Adenylyl Cyclase Demonstrated with a Novel Fluorescence Resonance Energy Transfer SensorA novel mechanism for adenylyl cyclase inhibition from the crystal structure of its complex with catechol estrogen.The role of protein kinase A in the ethanol-induced increase in spontaneous GABA release onto cerebellar Purkinje neurons.Concepts of neural nitric oxide-mediated transmission.Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studies.Adenylyl cyclase--A-kinase anchoring protein complexes: the next dimension in cAMP signaling.Allosteric regulation of nucleotidyl cyclases: an emerging pharmacological target.International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases.Pharmacological profiling of the Dictyostelium adenylate cyclases ACA, ACB and ACG.Differential inhibition of adenylyl cyclase isoforms and soluble guanylyl cyclase by purine and pyrimidine nucleotides.2'(3')-O-(N-methylanthraniloyl)-substituted GTP analogs: a novel class of potent competitive adenylyl cyclase inhibitors.Mechanism of Galpha i-mediated inhibition of type V adenylyl cyclase.Effect of MANT-nucleotides on L-type calcium currents in murine cardiomyocytes.Modeling of Galpha(s) and Galpha(i) regulation of human type V and VI adenylyl cyclase.Structural basis for the inhibition of mammalian membrane adenylyl cyclase by 2 '(3')-O-(N-Methylanthraniloyl)-guanosine 5 '-triphosphate.Mammalian Nucleotidyl Cyclases and Their Nucleotide Binding Sites.An enzyme-linked receptor mechanism for nitric oxide-activated guanylyl cyclase.AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965.
P2860
Q24338288-D55BC9F9-21D0-4602-BFD9-3781C3303674Q24622606-2429BB56-355C-4D6D-A659-FEC850F34B59Q24670133-B8656633-7E56-43E2-AE81-26A31022FE68Q26781612-128064DC-33F4-4FC0-A9CA-847EE301CE31Q27000357-F4888763-FFDF-4359-90F0-13FF0EE068D7Q27311590-2D4939D4-8AD5-4AD1-8C54-78C5C0B9C0E9Q27676621-2F265294-BE8B-4B69-A963-1DE2FB9FF2BBQ28487548-745365E2-6EC1-4999-AA17-D4A1E9B286E6Q33352228-8B7064CA-1238-4A8F-B539-A86F8E9E0230Q33950415-9A8B4576-57D2-47B4-9661-1AAA75E08841Q33978117-23C91FB5-FAAC-4104-9ACB-D64BD874D758Q34453808-51671DE7-7B89-4210-8BEC-DFE4DCF8B8F6Q34978520-D6D153D8-B9FA-4ACC-89D8-E1504195E93DQ35121057-E3800AAC-EA49-4309-89B2-CE7CAD138247Q35543592-B67C3394-2A69-4B6F-B475-FCE07B22AA29Q35740305-B3E9D158-4EC6-479D-8EA3-CE440BD2DD7DQ35770186-37DEEB53-DED1-44C3-B36E-58E9C0D9C01FQ36287047-48CA3F37-7521-4DD0-9C3E-45F288C5A747Q36490627-19E4F324-0E1C-4638-8091-1F6156D03C84Q36497784-14D967F8-B718-4E22-B340-4C944AC57092Q36733470-1D6ECE9C-1666-4F67-985F-02E089E9893CQ36833617-7EA2ED76-53AF-46D1-8224-121076FD9156Q37018500-25EC7023-A6F7-432C-8F92-18CB428754FAQ37029494-24B335A3-3CEF-453D-9E1F-0FCBBD1DA1FEQ37307356-8B7B579E-6BE8-4BA9-9BE0-EFAD62E5A26AQ37415827-FB3CB4A4-23D8-41AD-9A23-9AD11189E84EQ38040779-CAC4D647-F73A-4A1F-A495-D8ECA29231B6Q39158851-A02009ED-0326-43B8-B3F0-BE303CD6FFF7Q40235876-E07B7B2E-15BB-4CF9-AEE4-0680FEE552C8Q40586309-478B0D9B-F897-4797-A200-1D5E551303DFQ40672995-174BA3E7-3C01-4018-AAB9-138AFDAFFCDDQ40726129-F1CEA381-AD96-42F0-9355-B37AE2AD0451Q42486657-525DEE8D-C783-44C9-9F0A-0FD59E47FF6CQ45151648-FCB81873-DBF9-4AC5-ADF2-612E72F2E5C9Q45182671-F51910CD-E695-400A-BFC9-0626FE04A482Q46452983-0854F33D-06AD-45B1-97D7-FDAD3C70A0B0Q46607492-81828EF9-1589-40DC-9363-74270A32AAB9Q52309562-050744D1-7E02-4841-AE6F-C7467BCB2EF2
P2860
The interactions of adenylate cyclases with P-site inhibitors.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The interactions of adenylate cyclases with P-site inhibitors.
@ast
The interactions of adenylate cyclases with P-site inhibitors.
@en
type
label
The interactions of adenylate cyclases with P-site inhibitors.
@ast
The interactions of adenylate cyclases with P-site inhibitors.
@en
prefLabel
The interactions of adenylate cyclases with P-site inhibitors.
@ast
The interactions of adenylate cyclases with P-site inhibitors.
@en
P2093
P1476
The interactions of adenylate cyclases with P-site inhibitors.
@en
P2093
P304
P356
10.1016/S0165-6147(99)01310-3
P577
1999-05-01T00:00:00Z