Disrupted differentiation and oncogenic transformation of lymphoid progenitors in E2A-HLF transgenic mice
about
Murine models of acute leukemia: important tools in current pediatric leukemia research.AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutationsRole for homodimerization in growth deregulation by E2a fusion proteins.E2A-HLF usurps control of evolutionarily conserved survival pathways.LMO2 expression reflects the different stages of blast maturation and genetic features in B-cell acute lymphoblastic leukemia and predicts clinical outcome.E2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause acute T-lymphoid or myeloid leukemias in mice.Conditional Expression of E2A-HLF Induces B-Cell Precursor Death and Myeloproliferative-Like Disease in Knock-In Mice.Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.DNMT3A Arg882 mutation drives chronic myelomonocytic leukemia through disturbing gene expression/DNA methylation in hematopoietic cells.Genetically engineered mouse models of human B-cell precursor leukemias.Transformation of bone marrow B-cell progenitors by E2a-Hlf requires coexpression of Bcl-2.SSBP2 is an in vivo tumor suppressor and regulator of LDB1 stability.NGS-based methylation profiling differentiates TCF3-HLF and TCF3-PBX1 positive B-cell acute lymphoblastic leukemia.Identification of Zfp521/ZNF521 as a cooperative gene for E2A-HLF to develop acute B-lineage leukemia.Hypercalcemia in childhood acute lymphoblastic leukemia: frequent implication of parathyroid hormone-related peptide and E2A-HLF from translocation 17;19.
P2860
Q33606018-59607673-E0E0-43B1-84F0-736A123944B1Q33943238-89A4A2C8-F256-4238-97F0-EEC13EADEB51Q33964971-39D17C86-998A-49B8-94C1-E69A7071E54BQ34405477-32379AE9-1B8D-43DE-8E80-FCB0A63565C8Q35082503-FBCF9693-62C5-409E-A0B5-0912549E7A55Q35544255-5E50C244-EE83-4FBF-94A0-BC6C664095CBQ35847141-9F8FAB97-4A75-43F9-AA20-05A2C6CCDAE9Q36154689-297D1E5F-A21F-4667-81BE-1ACE52364DFCQ37599843-D683C7D2-65E4-44C6-8EB5-76771BFF9495Q38285177-A70C90FD-A334-4D16-9627-77C293CB8079Q39681536-56F08C64-03D7-4742-BAA4-32006265E5A0Q40810218-E4AB1D23-FFBE-456B-83BA-C429BDBED63FQ47563344-E4C26B9A-BDA7-4AA6-8A4E-E61695C1ACC0Q51918384-CD45C0A7-E816-4C29-82E3-3C244A4DEEACQ54566038-8C1CB2AC-79B9-46B4-A181-902EE5EB946F
P2860
Disrupted differentiation and oncogenic transformation of lymphoid progenitors in E2A-HLF transgenic mice
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Disrupted differentiation and ...... ors in E2A-HLF transgenic mice
@ast
Disrupted differentiation and ...... ors in E2A-HLF transgenic mice
@en
type
label
Disrupted differentiation and ...... ors in E2A-HLF transgenic mice
@ast
Disrupted differentiation and ...... ors in E2A-HLF transgenic mice
@en
prefLabel
Disrupted differentiation and ...... ors in E2A-HLF transgenic mice
@ast
Disrupted differentiation and ...... ors in E2A-HLF transgenic mice
@en
P2093
P2860
P356
P1476
Disrupted differentiation and ...... ors in E2A-HLF transgenic mice
@en
P2093
P2860
P304
P356
10.1128/MCB.19.6.4443
P407
P577
1999-06-01T00:00:00Z