DNA replication of human papillomavirus type 31 is modulated by elements of the upstream regulatory region that lie 5' of the minimal origin
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Role of the PDZ domain-binding motif of the oncoprotein E6 in the pathogenesis of human papillomavirus type 31Genetic analysis of the human papillomavirus type 31 differentiation-dependent late promoter.Variant upstream regulatory region sequences differentially regulate human papillomavirus type 16 DNA replication throughout the viral life cycle.Differentiation-dependent chromatin rearrangement coincides with activation of human papillomavirus type 31 late gene expression.Early polyadenylation signals of human papillomavirus type 31 negatively regulate capsid gene expression.The spacing between adjacent binding sites in the family of repeats affects the functions of Epstein-Barr nuclear antigen 1 in transcription activation and stable plasmid maintenanceNuclear export of human papillomavirus type 31 E1 is regulated by Cdk2 phosphorylation and required for viral genome maintenance.Genetic analysis of cis regulatory elements within the 5' region of the human papillomavirus type 31 upstream regulatory region during different stages of the viral life cycleThe upstream regulatory region of human papillomavirus type 31 is insensitive to glucocorticoid induction.Human papillomavirus type 16 (HPV-16) genomes integrated in head and neck cancers and in HPV-16-immortalized human keratinocyte clones express chimeric virus-cell mRNAs similar to those found in cervical cancers.Human papillomavirus type 31 replication modes during the early phases of the viral life cycle depend on transcriptional and posttranscriptional regulation of E1 and E2 expression.Human papillomavirus type 31 oncoproteins E6 and E7 are required for the maintenance of episomes during the viral life cycle in normal human keratinocytes.Post-Transcriptional Regulation of KLF4 by High-Risk Human Papillomaviruses Is Necessary for the Differentiation-Dependent Viral Life Cycle.Human papillomavirus E1 helicase interacts with the WD repeat protein p80 to promote maintenance of the viral genome in keratinocytes.Metaphase chromosome tethering is necessary for the DNA synthesis and maintenance of oriP plasmids but is insufficient for transcription activation by Epstein-Barr nuclear antigen 1.Genetic and biochemical analysis of cis regulatory elements within the keratinocyte enhancer region of the human papillomavirus type 31 upstream regulatory region during different stages of the viral life cycle.Epstein-Barr Nuclear Antigen 1 modulates replication of oriP-plasmids by impeding replication and transcription fork migration through the family of repeats.Recombination-dependent oligomerization of human papillomavirus genomes upon transient DNA replication.Upstream regulatory region alterations found in human papillomavirus type 16 (HPV-16) isolates from cervical carcinomas increase transcription, ori function, and HPV immortalization capacity in cultureHuman papillomavirus (HPV) type 18 induces extended growth in primary human cervical, tonsillar, or foreskin keratinocytes more effectively than other high-risk mucosal HPVs.The amino terminus of Epstein-Barr Virus (EBV) nuclear antigen 1 contains AT hooks that facilitate the replication and partitioning of latent EBV genomes by tethering them to cellular chromosomesOrientation of a novel DNA binding site affects human papillomavirus-mediated transcription and replication.Regulation of human papillomavirus type 31 gene expression during the differentiation-dependent life cycle through histone modifications and transcription factor bindingDifferentiation-dependent changes in levels of C/EBPβ repressors and activators regulate human papillomavirus type 31 late gene expression.The E8E2C protein, a negative regulator of viral transcription and replication, is required for extrachromosomal maintenance of human papillomavirus type 31 in keratinocytes.Infectious virions produced from a human papillomavirus type 18/16 genomic DNA chimera.Human papillomavirus type 31b infection of human keratinocytes and the onset of early transcription.Functional mapping of the human papillomavirus type 16 E1 cistron.The E8--E2 gene product of human papillomavirus type 16 represses early transcription and replication but is dispensable for viral plasmid persistence in keratinocytes.Persistence of an Oncogenic Papillomavirus Genome Requires cis Elements from the Viral Transcriptional Enhancer.
P2860
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P2860
DNA replication of human papillomavirus type 31 is modulated by elements of the upstream regulatory region that lie 5' of the minimal origin
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
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1999年の論文
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1999年論文
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1999年論文
@zh-hant
1999年論文
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1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
DNA replication of human papil ...... t lie 5' of the minimal origin
@ast
DNA replication of human papil ...... t lie 5' of the minimal origin
@en
type
label
DNA replication of human papil ...... t lie 5' of the minimal origin
@ast
DNA replication of human papil ...... t lie 5' of the minimal origin
@en
prefLabel
DNA replication of human papil ...... t lie 5' of the minimal origin
@ast
DNA replication of human papil ...... t lie 5' of the minimal origin
@en
P2093
P2860
P1433
P1476
DNA replication of human papil ...... t lie 5' of the minimal origin
@en
P2093
P2860
P304
P577
1999-03-01T00:00:00Z