SLAT/Def6 plays a critical role in the development of Th17 cell-mediated experimental autoimmune encephalomyelitis.
about
A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28SWAP-70-like adapter of T cells: a novel Lck-regulated guanine nucleotide exchange factor coordinating actin cytoskeleton reorganization and Ca2+ signaling in T cellsIBP regulates epithelial-to-mesenchymal transition and the motility of breast cancer cells via Rac1, RhoA and Cdc42 signaling pathways.Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice.Dual regulation of IRF4 function in T and B cells is required for the coordination of T-B cell interactions and the prevention of autoimmunity.SLAT/Def6 plays a critical role in the pathogenic process of experimental autoimmune uveitis (EAU).DEF6, a novel substrate for the Tec kinase ITK, contains a glutamine-rich aggregation-prone region and forms cytoplasmic granules that co-localize with P-bodies.SLAT promotes TCR-mediated, Rap1-dependent LFA-1 activation and adhesion through interaction of its PH domain with Rap1.SLAT regulates CD8+ T cell clonal expansion in a Cdc42- and NFAT1-dependent mannerDEF6 expression in ovarian carcinoma correlates with poor patient survival.IBP-mediated suppression of autophagy promotes growth and metastasis of breast cancer cells via activating mTORC2/Akt/FOXO3a signaling pathway.Ectopically expressed IBP promotes cell proliferation in oral squamous cell carcinoma.Identification of a Novel Alternatively Spliced Form of Inflammatory Regulator SWAP-70-Like Adapter of T Cells.Phosphoproteomics Reveals Regulatory T Cell-Mediated DEF6 Dephosphorylation That Affects Cytokine Expression in Human Conventional T Cells.Overexpression and clinical significance of IBP in epithelial ovarian carcinoma.
P2860
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P2860
SLAT/Def6 plays a critical role in the development of Th17 cell-mediated experimental autoimmune encephalomyelitis.
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
SLAT/Def6 plays a critical rol ...... autoimmune encephalomyelitis.
@ast
SLAT/Def6 plays a critical rol ...... autoimmune encephalomyelitis.
@en
type
label
SLAT/Def6 plays a critical rol ...... autoimmune encephalomyelitis.
@ast
SLAT/Def6 plays a critical rol ...... autoimmune encephalomyelitis.
@en
prefLabel
SLAT/Def6 plays a critical rol ...... autoimmune encephalomyelitis.
@ast
SLAT/Def6 plays a critical rol ...... autoimmune encephalomyelitis.
@en
P2093
P2860
P356
P1476
SLAT/Def6 plays a critical rol ...... autoimmune encephalomyelitis.
@en
P2093
Amnon Altman
Ann J Canonigo-Balancio
Camille Fos
Stéphane Bécart
Thomas Prod'homme
P2860
P304
P356
10.4049/JIMMUNOL.0902573
P407
P577
2009-11-13T00:00:00Z