A conserved tryptophan-rich motif in the membrane-proximal region of the human immunodeficiency virus type 1 gp41 ectodomain is important for Env-mediated fusion and virus infectivity.
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Crystal structure of HIV-1 gp41 including both fusion peptide and membrane proximal external regionsCryo-electron tomographic structure of an immunodeficiency virus envelope complex in situCloaked similarity between HIV-1 and SARS-CoV suggests an anti-SARS strategyA Blueprint for HIV Vaccine DiscoveryInduction of antibodies in rhesus macaques that recognize a fusion-intermediate conformation of HIV-1 gp41Membrane interface-interacting sequences within the ectodomain of the human immunodeficiency virus type 1 envelope glycoprotein: putative role during viral fusionStructures and Mechanisms of Viral Membrane Fusion Proteins: Multiple Variations on a Common ThemeLipids and membrane microdomains in HIV-1 replicationStructure of the HIV-1 gp41 Membrane-Proximal Ectodomain Region in a Putative Prefusion Conformation † , ‡A Conformational Switch in Human Immunodeficiency Virus gp41 Revealed by the Structures of Overlapping Epitopes Recognized by Neutralizing AntibodiesCrystallographic Definition of the Epitope Promiscuity of the Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2F5: Vaccine Design ImplicationsCharge-Surrounded Pockets and Electrostatic Interactions with Small Ions Modulate the Activity of Retroviral Fusion ProteinsDisruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41Structural Basis for HIV-1 Neutralization by 2F5-Like Antibodies m66 and m66.6Structure of an HIV-1-neutralizing antibody target, the lipid-bound gp41 envelope membrane proximal region trimerWhere in the Cell Are You? Probing HIV-1 Host Interactions through Advanced Imaging TechniquesMechanism of inhibition of enveloped virus membrane fusion by the antiviral drug arbidolRecognition of membrane-bound fusion-peptide/MPER complexes by the HIV-1 neutralizing 2F5 antibody: implications for anti-2F5 immunogenicityErythrocyte Binding Activity Displayed by a Selective Group of Plasmodium vivax Tryptophan Rich Antigens Is Inhibited by Patients' AntibodiesFunctional stability of unliganded envelope glycoprotein spikes among isolates of human immunodeficiency virus type 1 (HIV-1)Immunogenicity of membrane-bound HIV-1 gp41 membrane-proximal external region (MPER) segments is dominated by residue accessibility and modulated by stereochemistry.Generation of Long-Lived Bone Marrow Plasma Cells Secreting Antibodies Specific for the HIV-1 gp41 Membrane-Proximal External Region in the Absence of Polyreactivity.C-terminal tail of human immunodeficiency virus gp41: functionally rich and structurally enigmatic.Sequential roles of receptor binding and low pH in forming prehairpin and hairpin conformations of a retroviral envelope glycoproteinHuman Ubc9 contributes to production of fully infectious human immunodeficiency virus type 1 virionsIdentification of the membrane-active regions of the severe acute respiratory syndrome coronavirus spike membrane glycoprotein using a 16/18-mer peptide scan: implications for the viral fusion mechanismBroadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.Fine definition of the epitope on the gp41 glycoprotein of human immunodeficiency virus type 1 for the neutralizing monoclonal antibody 2F5.Broad neutralization of human immunodeficiency virus type 1 (HIV-1) elicited from human rhinoviruses that display the HIV-1 gp41 ELDKWA epitope4E10-resistant HIV-1 isolated from four subjects with rare membrane-proximal external region polymorphismsAromatic residues at the edge of the antibody combining site facilitate viral glycoprotein recognition through membrane interactions.Relationship between antibody 2F5 neutralization of HIV-1 and hydrophobicity of its heavy chain third complementarity-determining regionThe conserved glycine-rich segment linking the N-terminal fusion peptide to the coiled coil of human T-cell leukemia virus type 1 transmembrane glycoprotein gp21 is a determinant of membrane fusion function.Lytic Inactivation of Human Immunodeficiency Virus by Dual Engagement of gp120 and gp41 Domains in the Virus Env Protein Trimer.The three lives of viral fusion peptidesStructure-function studies of the self-assembly domain of the human immunodeficiency virus type 1 transmembrane protein gp41.The membrane-proximal stem region of vesicular stomatitis virus G protein confers efficient virus assembly.Genetic evidence for an interaction between human immunodeficiency virus type 1 matrix and alpha-helix 2 of the gp41 cytoplasmic tail.Plasmodium vivax tryptophan-rich antigen PvTRAg33.5 contains alpha helical structure and multidomain architecture.Role of the membrane-proximal domain in the initial stages of human immunodeficiency virus type 1 envelope glycoprotein-mediated membrane fusion.
P2860
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P2860
A conserved tryptophan-rich motif in the membrane-proximal region of the human immunodeficiency virus type 1 gp41 ectodomain is important for Env-mediated fusion and virus infectivity.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
A conserved tryptophan-rich mo ...... fusion and virus infectivity.
@ast
A conserved tryptophan-rich mo ...... fusion and virus infectivity.
@en
type
label
A conserved tryptophan-rich mo ...... fusion and virus infectivity.
@ast
A conserved tryptophan-rich mo ...... fusion and virus infectivity.
@en
prefLabel
A conserved tryptophan-rich mo ...... fusion and virus infectivity.
@ast
A conserved tryptophan-rich mo ...... fusion and virus infectivity.
@en
P2093
P2860
P1433
P1476
A conserved tryptophan-rich mo ...... d fusion and virus infectivity
@en
P2093
P2860
P304
P577
1999-03-01T00:00:00Z