MMTV-Espl1 transgenic mice develop aneuploid, estrogen receptor alpha (ERα)-positive mammary adenocarcinomas. - Wikidata - awgldk - TriplyDB

MMTV-Espl1 transgenic mice develop aneuploid, estrogen receptor alpha (ERα)-positive mammary adenocarcinomas.

MMTV-Espl1 transgenic mice develop aneuploid, estrogen receptor alpha (ERα)-positive mammary adenocarcinomas.

http://www.wikidata.org/entity/Q33657478

about

Genetically engineered ERα-positive breast cancer mouse models.E2F activators signal and maintain centrosome amplification in breast cancer cells.The CINSARC signature as a prognostic marker for clinical outcome in multiple neoplasms Overexpression and constitutive nuclear localization of cohesin protease Separase protein correlates with high incidence of relapse and reduced overall survival in glioblastoma multiforme Clonal Evolution and Blast Crisis Correlate with Enhanced Proteolytic Activity of Separase in BCR-ABL b3a2 Fusion Type CML under Imatinib Therapy Measurement of separase proteolytic activity in single living cells by a fluorogenic flow cytometry assay c-MYB is a transcriptional regulator of ESPL1/Separase in BCR-ABL-positive chronic myeloid leukemia Separase is a marker for prognosis and mitotic activity in breast cancer.Separase: Function Beyond Cohesion Cleavage and an Emerging Oncogene.Living in CIN: Mitotic Infidelity and Its Consequences for Tumor Promotion and Suppression.Biology and insights into the role of cohesin protease separase in human malignancies.Combined analysis identifies six genes correlated with augmented malignancy from non-small cell to small cell lung cancer.Positive and negative regulation of vertebrate separase by Cdk1-cyclin B1 may explain why securin is dispensable.Increased separase activity and occurrence of centrosome aberrations concur with transformation of MDS.Aging Mouse Models Reveal Complex Tumor-Microenvironment Interactions in Cancer Progression.Separase Inhibitor Sepin-1 Inhibits Foxm1 Expression and Breast Cancer Cell Growth.The Metabolism of Separase Inhibitor Sepin-1 in Human, Mouse, and Rat Liver Microsomes.Expression and prognostic value of cell-cycle-associated genes in gastric adenocarcinoma.

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P2860

MMTV-Espl1 transgenic mice develop aneuploid, estrogen receptor alpha (ERα)-positive mammary adenocarcinomas.

http://www.wikidata.org/entity/Q33657478

description

2013 nî lūn-bûn

@nan

2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

MMTV-Espl1 transgenic mice dev ...... itive mammary adenocarcinomas.

@ast

MMTV-Espl1 transgenic mice dev ...... itive mammary adenocarcinomas.

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type

label

MMTV-Espl1 transgenic mice dev ...... itive mammary adenocarcinomas.

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MMTV-Espl1 transgenic mice dev ...... itive mammary adenocarcinomas.

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prefLabel

MMTV-Espl1 transgenic mice dev ...... itive mammary adenocarcinomas.

@ast

MMTV-Espl1 transgenic mice dev ...... itive mammary adenocarcinomas.

@en

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MMTV-Espl1 transgenic mice dev ...... itive mammary adenocarcinomas.

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P2093

Daniel Medina

http://www.w3.org/2001/XMLSchema#string

David G Edwards

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Debananda Pati

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Gouqing Ge

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Malini Mukherjee

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Nenggang Zhang

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Pavel Sumazin

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Pulivarthi H Rao

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Shyam K Sharan

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P2860

Comprehensive molecular portraits of human breast tumours

MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1

Genetic instability of cancer cells is proportional to their degree of aneuploidy

Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells

Down-regulation of p21WAF1/CIP1 or p27Kip1 abrogates antiestrogen-mediated cell cycle arrest in human breast cancer cells

Cyclin D1 in breast cancer pathogenesis.

Separase, polo kinase, the kinetochore protein Slk19, and Spo12 function in a network that controls Cdc14 localization during early anaphase.

About GATA3, HNF3A, and XBP1, three genes co-expressed with the oestrogen receptor-alpha gene (ESR1) in breast cancer

Stable 'portrait' of breast tumors during progression: data from biology, pathology and genetics

Separase loss of function cooperates with the loss of p53 in the initiation and progression of T- and B-cell lymphoma, leukemia and aneuploidy in mice

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5511-5522

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10.1038/ONC.2013.493

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