Downregulation of Rap1GAP through epigenetic silencing and loss of heterozygosity promotes invasion and progression of thyroid tumors - Wikidata - awgldk - TriplyDB

Downregulation of Rap1GAP through epigenetic silencing and loss of heterozygosity promotes invasion and progression of thyroid tumors

Downregulation of Rap1GAP through epigenetic silencing and loss of heterozygosity promotes invasion and progression of thyroid tumors

http://www.wikidata.org/entity/Q33658293

about

Genetic and epigenetic alterations in differentiated thyroid carcinoma.Epigenetic Mechanism in Regulation of Endothelial Function by Disturbed Flow: Induction of DNA Hypermethylation by DNMT1.Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster.Copy number alteration and uniparental disomy analysis categorizes Japanese papillary thyroid carcinomas into distinct groups.Differences in gastric carcinoma microenvironment stratify according to EBV infection intensity: implications for possible immune adjuvant therapy.The role of epigenetic alterations in papillary thyroid carcinogenesis.The tumor suppressor gene rap1GAP is silenced by miR-101-mediated EZH2 overexpression in invasive squamous cell carcinoma Prostaglandin E2 regulates renal cell carcinoma invasion through the EP4 receptor-Rap GTPase signal transduction pathway.PLK1 and β-TrCP-dependent ubiquitination and degradation of Rap1GAP controls cell proliferation Rap1GAP impairs cell-matrix adhesion in the absence of effects on cell-cell adhesion Breast cancer cell migration is regulated through junctional adhesion molecule-A-mediated activation of Rap1 GTPase.Rap1GAP regulates renal cell carcinoma invasion.Epigenetics modifications and therapeutic prospects in human thyroid cancer.Thyroid cancer: pathogenesis and targeted therapy Reactivation of the silenced thyroid hormone receptor β gene expression delays thyroid tumor progression Mesenchymal high-grade glioma is maintained by the ID-RAP1 axis.Tumor cell migration and invasion are enhanced by depletion of Rap1 GTPase-activating protein (Rap1GAP)Podocyte-specific RAP1GAP expression contributes to focal segmental glomerulosclerosis-associated glomerular injury Low expression of Rap1GAP is associated with epithelial-mesenchymal transition (EMT) and poor prognosis in gastric cancer.Roles of Rap1 signaling in tumor cell migration and invasion Genetics and epigenetics of sporadic thyroid cancer.Epigenetic modifications in human thyroid cancer.Molecular Aberrance in Papillary Thyroid Microcarcinoma Bearing High Aggressiveness: Identifying a "Tibetan Mastiff Dog" From Puppies.Nuclear SIPA1 activates integrin β1 promoter and promotes invasion of breast cancer cells.Curcumin inhibits the metastasis of K1 papillary thyroid cancer cells via modulating E-cadherin and matrix metalloproteinase-9 expression.RAP1GAP inhibits cytoskeletal remodeling and motility in thyroid cancer cells.Histone deacetylase inhibitors upregulate Rap1GAP and inhibit Rap activity in thyroid tumor cells.Rap1 mediates galanin receptor 2-induced proliferation and survival in squamous cell carcinoma TIMP3 regulates migration, invasion and in vivo tumorigenicity of thyroid tumor cells.Downregulation of Rap1GAP in human tumor cells alters cell/matrix and cell/cell adhesion.DNA methylation state of the galectin-3 gene represents a potential new marker of thyroid malignancy.Prognostic Classifier Based on Genome-Wide DNA Methylation Profiling in Well-Differentiated Thyroid Tumors.MiR-196a binding-site SNP regulates RAP1A expression contributing to esophageal squamous cell carcinoma risk and metastasis.The downregulation of Rap1 GTPase-activating protein is associated with a poor prognosis in colorectal cancer and may impact on tumor progression.The management of thyroid nodules and cancer in the molecular era Downregulation of Rap1Gap: A Switch from DCIS to Invasive Breast Carcinoma via ERK/MAPK Activation

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Downregulation of Rap1GAP through epigenetic silencing and loss of heterozygosity promotes invasion and progression of thyroid tumors

http://www.wikidata.org/entity/Q33658293

description

2010 nî lūn-bûn

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2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Downregulation of Rap1GAP thro ...... progression of thyroid tumors

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Downregulation of Rap1GAP thro ...... progression of thyroid tumors

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type

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Downregulation of Rap1GAP thro ...... progression of thyroid tumors

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Downregulation of Rap1GAP thro ...... progression of thyroid tumors

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prefLabel

Downregulation of Rap1GAP thro ...... progression of thyroid tumors

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Downregulation of Rap1GAP thro ...... progression of thyroid tumors

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0008-5472.CAN-09-2812

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Cancer Research

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Downregulation of Rap1GAP thro ...... progression of thyroid tumors

@en

P2093

Daniel Hochbaum

http://www.w3.org/2001/XMLSchema#string

Daniel L Altschuler

http://www.w3.org/2001/XMLSchema#string

Hui Zuo

http://www.w3.org/2001/XMLSchema#string

James Dipaola

http://www.w3.org/2001/XMLSchema#string

Manoj Gandhi

http://www.w3.org/2001/XMLSchema#string

Martin M Edreira

http://www.w3.org/2001/XMLSchema#string

Ping Zhang

http://www.w3.org/2001/XMLSchema#string

Viktoria Evdokimova

http://www.w3.org/2001/XMLSchema#string

Vishwajit L Nimgaonkar

http://www.w3.org/2001/XMLSchema#string

Yuri E Nikiforov

http://www.w3.org/2001/XMLSchema#string

P2860

Localization of the rap1GAP catalytic domain and sites of phosphorylation by mutational analysis

The consensus coding sequences of human breast and colorectal cancers

Loss of Rap1GAP in papillary thyroid cancer

Rap1GAP inhibits tumor growth in oropharyngeal squamous cell carcinoma

Downregulation of Rap1GAP contributes to Ras transformation

Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation

MethPrimer: designing primers for methylation PCRs

Conditional activation of RET/PTC3 and BRAFV600E in thyroid cells is associated with gene expression profiles that predict a preferential role of BRAF in extracellular matrix remodeling.

BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas.

Rising thyroid cancer incidence in the United States by demographic and tumor characteristics, 1980-2005.

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1389-1397

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scholarly article

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10.1158/0008-5472.CAN-09-2812

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4

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70

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2010-02-02T00:00:00Z

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20124489

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2822891

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