Fluorous iminoalditols: a new family of glycosidase inhibitors and pharmacological chaperones. - Wikidata - awgldk - TriplyDB

Fluorous iminoalditols: a new family of glycosidase inhibitors and pharmacological chaperones.

Fluorous iminoalditols: a new family of glycosidase inhibitors and pharmacological chaperones.

http://www.wikidata.org/entity/Q33660528

about

Selection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain.Candidate molecules for chemical chaperone therapy of GM1-gangliosidosis.Identification and characterization of pharmacological chaperones to correct enzyme deficiencies in lysosomal storage disorders.Pharmacological chaperones for enzyme enhancement therapy in genetic diseases.Medicinal applications of perfluoroalkylated chain-containing compounds.Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseases.Fluorous iminoalditols act as effective pharmacological chaperones against gene products from GLB₁ alleles causing GM1-gangliosidosis and Morquio B disease.A bicyclic 1-deoxygalactonojirimycin derivative as a novel pharmacological chaperone for GM1 gangliosidosis.Tuning protein folding in lysosomal storage diseases: the chemistry behind pharmacological chaperones.

P2860

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P2860

Fluorous iminoalditols: a new family of glycosidase inhibitors and pharmacological chaperones.

http://www.wikidata.org/entity/Q33660528

description

2010 nî lūn-bûn

@nan

2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Fluorous iminoalditols: a new ...... nd pharmacological chaperones.

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Fluorous iminoalditols: a new ...... nd pharmacological chaperones.

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type

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Fluorous iminoalditols: a new ...... nd pharmacological chaperones.

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Fluorous iminoalditols: a new ...... nd pharmacological chaperones.

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Fluorous iminoalditols: a new ...... nd pharmacological chaperones.

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Fluorous iminoalditols: a new ...... nd pharmacological chaperones.

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Fluorous iminoalditols: a new ...... and pharmacological chaperones

@en

P2093

Andreas J Steiner

http://www.w3.org/2001/XMLSchema#string

Arnold E Stütz

http://www.w3.org/2001/XMLSchema#string

Brigitte A Rigat

http://www.w3.org/2001/XMLSchema#string

Carina Illaszewicz

http://www.w3.org/2001/XMLSchema#string

Chris A Tarling

http://www.w3.org/2001/XMLSchema#string

Don J Mahuran

http://www.w3.org/2001/XMLSchema#string

Eduard Paschke

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Elisabeth Scheucher

http://www.w3.org/2001/XMLSchema#string

Georg Schitter

http://www.w3.org/2001/XMLSchema#string

Gerit Pototschnig

http://www.w3.org/2001/XMLSchema#string

P2860

The iminosugar isofagomine increases the activity of N370S mutant acid beta-glucosidase in Gaucher fibroblasts by several mechanisms

6-Amino-6-deoxy-5,6-di-N-(N'-octyliminomethylidene)nojirimycin: synthesis, biological evaluation, and crystal structure in complex with acid beta-glucosidase

Lending a helping hand, screening chemical libraries for compounds that enhance beta-hexosaminidase A activity in GM2 gangliosidosis cells

Identification and characterization of ambroxol as an enzyme enhancement agent for Gaucher disease

Survival of mammals breathing organic liquids equilibrated with oxygen at atmospheric pressure.

Fluorous-based small-molecule microarrays for protein, antibody and enzyme screening.

The pharmacological chaperone isofagomine increases the activity of the Gaucher disease L444P mutant form of beta-glucosidase.

Pharmacological enhancement of beta-hexosaminidase activity in fibroblasts from adult Tay-Sachs and Sandhoff Patients.

Chemical chaperones increase the cellular activity of N370S beta -glucosidase: a therapeutic strategy for Gaucher disease.

Chaperone therapy for neuronopathic lysosomal diseases: competitive inhibitors as chemical chaperones for enhancement of mutant enzyme activities

P304

2026-2033

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scholarly article

P356

10.1002/CBIC.201000192

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14

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11

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2010-09-01T00:00:00Z

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45661543

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20715263

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P921

molecular chaperones

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3198847

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