A transdominant tat mutant that inhibits tat-induced gene expression from the human immunodeficiency virus long terminal repeat.
about
Inhibition of HIV-1 Tat-mediated LTR transactivation and HIV-1 infection by anti-Tat single chain intrabodiesEngineering T Cells to Functionally Cure HIV-1 InfectionDecoy approach using RNA-DNA chimera oligonucleotides to inhibit the regulatory function of human immunodeficiency virus type 1 Rev proteinIsolation of efficient antivirals: genetic suppressor elements against HIV-1.Potent inhibition of HIV-1 replication by a Tat mutant.Intranuclear topological distribution of HIV-1 trans-activators.Human immunodeficiency virus gene regulation as a target for antiviral chemotherapy.Inhibition of human immunodeficiency virus type 1 Tat activity by coexpression of heterologous trans activators.Functional comparison of the basic domains of the Tat proteins of human immunodeficiency virus types 1 and 2 in trans activation.Novel macromolecular inhibitors of human immunodeficiency virus-1 protease.Nullbasic, a potent anti-HIV tat mutant, induces CRM1-dependent disruption of HIV rev traffickingAutophagy restricts HIV-1 infection by selectively degrading Tat in CD4+ T lymphocytes.Status of ribozyme and antisense-based developmental approaches for anti-HIV-1 therapy.A mutant tat protein inhibits HIV-1 reverse transcription by targeting the reverse transcription complex.Enhanced T cell engraftment after retroviral delivery of an antiviral gene in HIV-infected individualsHomologous interference resulting from the presence of defective particles of human immunodeficiency virus type 1.Altered cytokine expression in T lymphocytes from human immunodeficiency virus Tat transgenic miceTransduction of human CD34+ hematopoietic progenitor cells by a retroviral vector expressing an RRE decoy inhibits human immunodeficiency virus type 1 replication in myelomonocytic cells produced in long-term cultureInhibition of human immunodeficiency virus type 1 replication is enhanced by a combination of transdominant Tat and Rev proteinsInhibition of human immunodeficiency virus type 1 and type 2 Tat function by transdominant Tat protein localized to both the nucleus and cytoplasm.Nonviral and viral delivery of a human immunodeficiency virus protective gene into primary human T cellsDevelopment of a novel anti-HIV-1 agent from within: effect of chimeric Vpr-containing protease cleavage site residues on virus replicationImpact of Tat Genetic Variation on HIV-1 DiseaseTransdominant inhibition of wild-type human immunodeficiency virus type 2 replication by an envelope deletion mutant.Transdominant human T-cell lymphotropic virus type I TAX1 mutant that fails to localize to the nucleus.Mutations in the activation region of herpes simplex virus regulatory protein ICP27 can be trans dominant.trans-dominant mutants of E1A provide genetic evidence that the zinc finger of the trans-activating domain binds a transcription factorSite-specific cleavage of the transactivation response site of human immunodeficiency virus RNA with a tat-based chemical nucleaseGenetic regulation of human immunodeficiency virus.Shutdown of HIV-1 Transcription in T Cells by Nullbasic, a Mutant Tat ProteinInhibition of human immunodeficiency virus type 1 replication in human T cells by retroviral-mediated gene transfer of a dominant-negative Rev trans-activatorA conditionally replicating HIV-1 vector interferes with wild-type HIV-1 replication and spread.A point mutation in the HIV-1 Tat responsive element is associated with postintegration latency.The number of positively charged amino acids in the basic domain of Tat is critical for trans-activation and complex formation with TAR RNAExpression of a protective gene-prolongs survival of T cells in human immunodeficiency virus-infected patients.Potential mechanisms for cell-based gene therapy to treat HIV/AIDS.Effects of translation initiation factor eIF-5A on the functioning of human T-cell leukemia virus type I Rex and human immunodeficiency virus Rev inhibited trans dominantly by a Rex mutant deficient in RNA binding.Functional roles of HIV-1 Tat protein in the nucleus.Unusual Fusion Proteins of HIV-1A mutant Tat protein provides strong protection from HIV-1 infection in human CD4+ T cells.
P2860
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P2860
A transdominant tat mutant that inhibits tat-induced gene expression from the human immunodeficiency virus long terminal repeat.
description
1990 nî lūn-bûn
@nan
1990 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
A transdominant tat mutant tha ...... cy virus long terminal repeat.
@ast
A transdominant tat mutant tha ...... cy virus long terminal repeat.
@en
type
label
A transdominant tat mutant tha ...... cy virus long terminal repeat.
@ast
A transdominant tat mutant tha ...... cy virus long terminal repeat.
@en
prefLabel
A transdominant tat mutant tha ...... cy virus long terminal repeat.
@ast
A transdominant tat mutant tha ...... cy virus long terminal repeat.
@en
P2093
P2860
P356
P1476
A transdominant tat mutant tha ...... cy virus long terminal repeat.
@en
P2093
P2860
P304
P356
10.1073/PNAS.87.13.5079
P407
P577
1990-07-01T00:00:00Z