Designing blood-stage vaccines against Babesia bovis and B. bigemina.
about
Vaccines against bovine babesiosis: where we are now and possible roads aheadMolecular characterizations of three distinct Babesia gibsoni rhoptry-associated protein-1s (RAP-1s).Babesia bovis dihydroorotate dehydrogenase (BboDHODH) is a novel molecular target of drug for bovine babesiosisImmunization with recombinant surface antigen P50 of Babesia gibsoni expressed in insect cells induced parasite growth inhibition in dogs.Characterization of an intestinal epithelial cell receptor recognized by the Cryptosporidium parvum sporozoite ligand CSLDNA from protozoan parasites Babesia bovis, Trypanosoma cruzi, and T. brucei is mitogenic for B lymphocytes and stimulates macrophage expression of interleukin-12, tumor necrosis factor alpha, and nitric oxide.Innate resistance to Babesia infection is influenced by genetic background and gender.Efficacy of monoclonal antibodies against defined antigens for passive immunotherapy of chronic gastrointestinal cryptosporidiosis.Immunodominant epitopes in Babesia bovis rhoptry-associated protein 1 that elicit memory CD4(+)-T-lymphocyte responses in B. bovis-immune individuals are located in the amino-terminal domain.Evaluation of an enzyme-linked immunosorbent assay with recombinant rhoptry-associated protein 1 antigen against Babesia bovis for the detection of specific antibodies in cattleDevelopment of specific immunoglobulin Ga (IgGa) and IgGb antibodies correlates with control of parasitemia in Babesia equi InfectionImmunity following use of Australian tick fever vaccine: a review of the evidence.Babesia and its hosts: adaptation to long-lasting interactions as a way to achieve efficient transmissionResistance to acute babesiosis is associated with interleukin-12- and gamma interferon-mediated responses and requires macrophages and natural killer cellsTargeted surface expression of an exogenous antigen in stably transfected Babesia bovis.Conservation of Babesia bovis small heat shock protein (Hsp20) among strains and definition of T helper cell epitopes recognized by cattle with diverse major histocompatibility complex class II haplotypes.Macrophages are critical for cross-protective immunity conferred by Babesia microti against Babesia rodhaini infection in miceStimulation of T-helper cell gamma interferon and immunoglobulin G responses specific for Babesia bovis rhoptry-associated protein 1 (RAP-1) or a RAP-1 protein lacking the carboxy-terminal repeat region is insufficient to provide protective immunityProspects for recombinant vaccines against Babesia bovis and related parasites.Elongation factor-1α is a novel protein associated with host cell invasion and a potential protective antigen of Cryptosporidium parvum.Identification of Cowdria ruminantium antigens that stimulate proliferation of lymphocytes from cattle immunized by infection and treatment or with inactivated organisms.Identification and functional analysis of a novel mitochondria-localized 2-Cys peroxiredoxin, BbTPx-2, from Babesia bovis.Molecular basis for variable expression of merozoite surface antigen gp45 among American isolates of Babesia bigemina.Babesia bovis-stimulated macrophages express interleukin-1beta, interleukin-12, tumor necrosis factor alpha, and nitric oxide and inhibit parasite replication in vitro.The Babesia bovis merozoite surface antigen 2 locus contains four tandemly arranged and expressed genes encoding immunologically distinct proteins.Babesia bovis merozoite surface antigen 2 proteins are expressed on the merozoite and sporozoite surface, and specific antibodies inhibit attachment and invasion of erythrocytesMolecular Cloning and Characterization of Babesia orientalis Rhoptry Neck 2 BoRON2 Protein.Expression analysis and biological characterization of Babesia sp. BQ1 (Lintan) (Babesia motasi-like) rhoptry-associated protein 1 and its potential use in serodiagnosis via ELISA.Sequence variation and immunologic cross-reactivity among Babesia bovis merozoite surface antigen 1 proteins from vaccine strains and vaccine breakthrough isolates.Characterization of a phenotypically unique population of CD13+ dendritic cells resident in the spleen.The Babesia bovis merozoite surface antigen 1 hypervariable region induces surface-reactive antibodies that block merozoite invasion.C3 contributes to the cross-protective immunity induced by Babesia gibsoni phosphoriboprotein P0 against a lethal B. rodhaini infection.A novel neutralization sensitive and subdominant RAP-1-related antigen (RRA) is expressed by Babesia bovis merozoites.Babesia bovis: lipids from virulent S2P and attenuated R1A strains trigger differential signalling and inflammatory responses in bovine macrophages.Potential for recombinant Babesia bovis antigens to protect against a highly virulent isolate.Development of an Indirect ELISA Based on a Recombinant Chimeric Protein for the Detection of Antibodies against Bovine Babesiosis.
P2860
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P2860
Designing blood-stage vaccines against Babesia bovis and B. bigemina.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Designing blood-stage vaccines against Babesia bovis and B. bigemina.
@ast
Designing blood-stage vaccines against Babesia bovis and B. bigemina.
@en
type
label
Designing blood-stage vaccines against Babesia bovis and B. bigemina.
@ast
Designing blood-stage vaccines against Babesia bovis and B. bigemina.
@en
prefLabel
Designing blood-stage vaccines against Babesia bovis and B. bigemina.
@ast
Designing blood-stage vaccines against Babesia bovis and B. bigemina.
@en
P1476
Designing blood-stage vaccines against Babesia bovis and B. bigemina.
@en
P2093
P304
P356
10.1016/S0169-4758(99)01471-4
P577
1999-07-01T00:00:00Z