TOP2β is essential for ovarian follicles that are hypersensitive to chemotherapeutic drugs - Wikidata - awgldk - TriplyDB

TOP2β is essential for ovarian follicles that are hypersensitive to chemotherapeutic drugs

TOP2β is essential for ovarian follicles that are hypersensitive to chemotherapeutic drugs

http://www.wikidata.org/entity/Q33669250

about

Etoposide damages female germ cells in the developing ovary.Topoisomerase IIβ mediates the resistance of glioblastoma stem cells to replication stress-inducing drugs.Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders Roles of the C-terminal domains of topoisomerase IIα and topoisomerase IIβ in regulation of the decatenation checkpoint.Low-dose metronomic delivery of cyclophosphamide is less detrimental to granulosa cell viability, ovarian function, and fertility than maximum tolerated dose delivery in the mouse.The polycystic ovary syndrome-associated gene Yap1 is regulated by gonadotropins and sex steroid hormones in hyperandrogenism-induced oligo-ovulation in mouse.In situ cultured preantral follicles is a useful model to evaluate the effect of anticancer drugs on caprine folliculogenesis.

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TOP2β is essential for ovarian follicles that are hypersensitive to chemotherapeutic drugs

http://www.wikidata.org/entity/Q33669250

description

2013 nî lūn-bûn

@nan

2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年学术文章

@wuu

2013年学术文章

@zh-cn

2013年学术文章

@zh-hans

2013年学术文章

@zh-my

2013年学术文章

@zh-sg

2013年學術文章

@yue

name

TOP2β is essential for ovarian ...... tive to chemotherapeutic drugs

@ast

TOP2β is essential for ovarian ...... tive to chemotherapeutic drugs

@en

type

label

TOP2β is essential for ovarian ...... tive to chemotherapeutic drugs

@ast

TOP2β is essential for ovarian ...... tive to chemotherapeutic drugs

@en

prefLabel

TOP2β is essential for ovarian ...... tive to chemotherapeutic drugs

@ast

TOP2β is essential for ovarian ...... tive to chemotherapeutic drugs

@en

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Molecular Endocrinology

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TOP2β is essential for ovarian ...... tive to chemotherapeutic drugs

@en

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Chao Yu

http://www.w3.org/2001/XMLSchema#string

Dan Zhang

http://www.w3.org/2001/XMLSchema#string

Heng-Yu Fan

http://www.w3.org/2001/XMLSchema#string

Shu-Yan Ji

http://www.w3.org/2001/XMLSchema#string

Xiao-Meng Li

http://www.w3.org/2001/XMLSchema#string

Yin-Li Zhang

http://www.w3.org/2001/XMLSchema#string

Yong-Ping Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular requirements for doxorubicin-mediated death in murine oocytes

Topoisomerase IIalpha controls the decatenation checkpoint

Aberrant lamination in the cerebral cortex of mouse embryos lacking DNA topoisomerase IIbeta

Impairing follicle-stimulating hormone (FSH) signaling in vivo: targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance

Hormone-induced proliferation and differentiation of granulosa cells: a coordinated balance of the cell cycle regulators cyclin D2 and p27Kip1

p63 protects the female germ line during meiotic arrest

DNA topoisomerase IIbeta and neural development

CCAAT/enhancer-binding proteins (C/EBP)-α and -β are essential for ovulation, luteinization, and the expression of key target genes

Beta-catenin (CTNNB1) promotes preovulatory follicular development but represses LH-mediated ovulation and luteinization.

Cell type-specific targeted mutations of Kras and Pten document proliferation arrest in granulosa cells versus oncogenic insult to ovarian surface epithelial cells

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1678-1691

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scholarly article

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10.1210/ME.2013-1108

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10

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27

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