Fluorinated per-acetylated GalNAc metabolically alters glycan structures on leukocyte PSGL-1 and reduces cell binding to selectins.
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Leveraging fluorinated glucosamine action to boost antitumor immunityProtein glycosylation in cancers and its potential therapeutic applications in neuroblastoma2-Fluoro-L-Fucose Is a Metabolically Incorporated Inhibitor of Plant Cell Wall Polysaccharide FucosylationLipoxin A4 inhibits immune cell binding to salivary epithelium and vascular endothelium.Integration of systems glycobiology with bioinformatics toolboxes, glycoinformatics resources, and glycoproteomics data.P-selectin-mediated platelet activation promotes adhesion of non-small cell lung carcinoma cells on vascular endothelial cells under flowThe use of surface immobilization of P-selectin glycoprotein ligand-1 on mesenchymal stem cells to facilitate selectin mediated cell tethering and rollingST3Gal-4 is the primary sialyltransferase regulating the synthesis of E-, P-, and L-selectin ligands on human myeloid leukocytes.Synthesis and biological evaluation of a novel MUC1 glycopeptide conjugate vaccine candidate comprising a 4'-deoxy-4'-fluoro-Thomsen-Friedenreich epitope.Peracetylated 4-fluoro-glucosamine reduces the content and repertoire of N- and O-glycans without direct incorporation.Overexpression of α2,3sialyl T-antigen in breast cancer determined by miniaturized glycosyltransferase assays and confirmed using tissue microarray immunohistochemical analysis.A common sugar-nucleotide-mediated mechanism of inhibition of (glycosamino)glycan biosynthesis, as evidenced by 6F-GalNAc (Ac3)Pathobiological implications of mucin glycans in cancer: Sweet poison and novel targets.Silencing α1,3-fucosyltransferases in human leukocytes reveals a role for FUT9 enzyme during E-selectin-mediated cell adhesion.Competition between core-2 GlcNAc-transferase and ST6GalNAc-transferase regulates the synthesis of the leukocyte selectin ligand on human P-selectin glycoprotein ligand-1Distinct glycosyltransferases synthesize E-selectin ligands in human vs. mouse leukocytes.Base-modified UDP-sugars reduce cell surface levels of P-selectin glycoprotein 1 (PSGL-1) on IL-1β-stimulated human monocytes.Metabolic oligosaccharide engineering: implications for selectin-mediated adhesion and leukocyte extravasation.Understanding glycomechanics using mathematical modeling: a review of current approaches to simulate cellular glycosylation reaction networks.Downregulation of P-selectin glycoprotein ligand-1 as a potential anti-inflammatory mechanism.Synthesis and in vitro cytotoxicity of acetylated 3-fluoro, 4-fluoro and 3,4-difluoro analogs of D-glucosamine and D-galactosamineActivated platelets interact with lung cancer cells through P-selectin glycoprotein ligand-1.Glycomics for drug discovery: metabolic perturbation in androgen-independent prostate cancer cells induced by unnatural hexosamine mimics.Advances in cell surface glycoengineering reveal biological function.Metabolic inhibition of sialyl-Lewis X biosynthesis by 5-thiofucose remodels the cell surface and impairs selectin-mediated cell adhesion.Modulation of cellular adhesion by glycoengineering.Using CRISPR-Cas9 to quantify the contributions of O-glycans, N-glycans and Glycosphingolipids to human leukocyte-endothelium adhesionBiomimetic neural scaffolds: a crucial step towards optimal peripheral nerve regeneration.
P2860
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P2860
Fluorinated per-acetylated GalNAc metabolically alters glycan structures on leukocyte PSGL-1 and reduces cell binding to selectins.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Fluorinated per-acetylated Gal ...... ces cell binding to selectins.
@ast
Fluorinated per-acetylated Gal ...... ces cell binding to selectins.
@en
type
label
Fluorinated per-acetylated Gal ...... ces cell binding to selectins.
@ast
Fluorinated per-acetylated Gal ...... ces cell binding to selectins.
@en
prefLabel
Fluorinated per-acetylated Gal ...... ces cell binding to selectins.
@ast
Fluorinated per-acetylated Gal ...... ces cell binding to selectins.
@en
P2093
P2860
P1433
P1476
Fluorinated per-acetylated Gal ...... ces cell binding to selectins.
@en
P2093
Alexander Buffone
Dhananjay D Marathe
E V Chandrasekaran
Joseph T Y Lau
Khushi L Matta
Mehrab Nasirikenari
Robert D Locke
Sriram Neelamegham
P2860
P304
P356
10.1182/BLOOD-2009-07-231480
P407
P577
2009-12-08T00:00:00Z