DNA methylation profiles and their relationship with cytogenetic status in adult acute myeloid leukemia.
about
Chemotherapy-induced hypomethylation of N-myc downstream-regulated gene 4 in the bone marrow of patients with acute myeloid leukemia.Hypermethylation and down-regulation of DLEU2 in paediatric acute myeloid leukaemia independent of embedded tumour suppressor miR-15a/16-1.Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies.Leukemic mutations in the methylation-associated genes DNMT3A and IDH2 are rare events in pediatric AML: a report from the Children's Oncology GroupPrognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11q23/MLL-rearranged AML patients: results of an international studyValidation of DNA methylation to predict outcome in acute myeloid leukemia by use of xMELPDissecting the role of aberrant DNA methylation in human leukaemia.Epigenetic Aging Signatures Are Coherently Modified in CancerIdentification of differentially methylated markers among cytogenetic risk groups of acute myeloid leukemiaA critical appraisal of tools available for monitoring epigenetic changes in clinical samples from patients with myeloid malignancies.Molecular characteristics and chromatin texture features in acute promyelocytic leukemia.High expression of RUNX1 is associated with poorer outcomes in cytogenetically normal acute myeloid leukemia.Gene expression profiling of the DNMT3A R882 mutation in acute leukemia.Genetic hierarchy and temporal variegation in the clonal history of acute myeloid leukaemia.Induction of Chromosomal Instability via Telomere Dysfunction and Epigenetic Alterations in Myeloid NeoplasiaHypermethylation of the alternative AWT1 promoter in hematological malignancies is a highly specific marker for acute myeloid leukemias despite high expression levels.Molecular pathogenesis of core binding factor leukemia: current knowledge and future prospects.Epigenetic regulation of miRNA genes in acute leukemia.Molecular-based classification of acute myeloid leukemia and its role in directing rational therapy: personalized medicine for profoundly promiscuous proliferations.Role of epigenetics in chronic myeloid leukemiaOrigins of aberrant DNA methylation in acute myeloid leukemia.Precision medicine based on epigenomics: the paradigm of carcinoma of unknown primary.Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemiaIntegrated analysis of the molecular action of Vorinostat identifies epi-sensitised targets for combination therapy.Acute myeloid leukemia with the t(8;21) translocation: clinical consequences and biological implications.Truncated RUNX1 protein generated by a novel t(1;21)(p32;q22) chromosomal translocation impairs the proliferation and differentiation of human hematopoietic progenitors.Aberrant DNA methylation profile of chronic and transformed classic Philadelphia-negative myeloproliferative neoplasms.CpG island methylator phenotype and its relationship with prognosis in adult acute leukemia patients.MN1 overexpression is driven by loss of DNMT3B methylation activity in inv(16) pediatric AML.Chromatin modifications induced by the AML1-ETO fusion protein reversibly silence its genomic targets through AML1 and Sp1 binding motifs.Array-based DNA methylation profiling in acute myeloid leukaemia.CDKN2B Methylation Correlates with Survival in AML Patients.Integrated epigenetic and genetic analysis identifies markers of prognostic significance in pediatric acute myeloid leukemia.A whole genome methylation analysis of systemic lupus erythematosus: hypomethylation of the IL10 and IL1R2 promoters is associated with disease activity
P2860
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P2860
DNA methylation profiles and their relationship with cytogenetic status in adult acute myeloid leukemia.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
DNA methylation profiles and t ...... adult acute myeloid leukemia.
@ast
DNA methylation profiles and t ...... adult acute myeloid leukemia.
@en
type
label
DNA methylation profiles and t ...... adult acute myeloid leukemia.
@ast
DNA methylation profiles and t ...... adult acute myeloid leukemia.
@en
prefLabel
DNA methylation profiles and t ...... adult acute myeloid leukemia.
@ast
DNA methylation profiles and t ...... adult acute myeloid leukemia.
@en
P2093
P2860
P50
P1433
P1476
DNA methylation profiles and t ...... adult acute myeloid leukemia.
@en
P2093
Agustín Fernández
Francesco Acquadro
James C Mulloy
Javier Suela
Jose Roman-Gómez
José Cervera
Juan C Cigudosa
Mark Wunderlich
María José Calasanz
Sandra Rodriguez Perales
P2860
P304
P356
10.1371/JOURNAL.PONE.0012197
P407
P50
P577
2010-08-16T00:00:00Z