Subjects with early-onset type 2 diabetes show defective activation of the skeletal muscle PGC-1{alpha}/Mitofusin-2 regulatory pathway in response to physical activity
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Mitochondrial Quality Control and Muscle Mass MaintenanceSkeletal Muscle Mitochondrial Bioenergetics and Morphology in High Fat Diet Induced Obesity and Insulin Resistance: Focus on Dietary Fat SourceHeart failure and mitochondrial dysfunction: the role of mitochondrial fission/fusion abnormalities and new therapeutic strategiesImpaired mitochondrial dynamics and bioenergetics in diabetic skeletal muscleMitochondrial metabolism and the control of vascular smooth muscle cell proliferationEffects of high-intensity interval training and moderate-intensity continuous training on glycaemic control and skeletal muscle mitochondrial function in db/db mice.Mfn2 is critical for brown adipose tissue thermogenic functionLoss of Pgc-1α expression in aging mouse muscle potentiates glucose intolerance and systemic inflammationDifferent effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stressImpaired overload-induced hypertrophy is associated with diminished mTOR signaling in insulin-resistant skeletal muscle of the obese Zucker ratMuscle oxidative capacity during IL-6-dependent cancer cachexia.Curcumin restores mitochondrial functions and decreases lipid peroxidation in liver and kidneys of diabetic db/db mice.Mitophagy: therapeutic potentials for liver disease and beyond.Short term exercise induces PGC-1α, ameliorates inflammation and increases mitochondrial membrane proteins but fails to increase respiratory enzymes in aging diabetic hearts.Is there a metabolic program in the skeletal muscle of obese individuals?Insight into the impact of dietary saturated fat on tissue-specific cellular processes underlying obesity-related diseases.Mitochondrial dysregulation in the pathogenesis of diabetes: potential for mitochondrial biogenesis-mediated interventions.Gene and MicroRNA Expression Responses to Exercise; Relationship with Insulin SensitivityMitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis.Relationships between mitochondrial content and bioenergetics with obesity, body composition and fat distribution in healthy older adults.IL-6 regulation on skeletal muscle mitochondrial remodeling during cancer cachexia in the ApcMin/+ mouse.Mechanism of Activation-Induced Downregulation of Mitofusin 2 in Human Peripheral Blood T CellsThe Association of Mitofusion-2 Gene Polymorphisms with Susceptibility of Essential Hypertension in Northern Han Chinese Population.Mitochondrial morphology, topology, and membrane interactions in skeletal muscle: a quantitative three-dimensional electron microscopy studySkeletal intramyocellular lipid metabolism and insulin resistance.Mitofusin-2 ameliorates high-fat diet-induced insulin resistance in liver of ratsThe emerging role of skeletal muscle oxidative metabolism as a biological target and cellular regulator of cancer-induced muscle wastingMild fasting hyperglycemia shifts fuel reliance toward fat during exercise in adults with impaired glucose toleranceClinical significance of mitofusin-2 and its signaling pathways in hepatocellular carcinoma.Coordinated Upregulation of Mitochondrial Biogenesis and Autophagy in Breast Cancer Cells: The Role of Dynamin Related Protein-1 and Implication for Breast Cancer Treatment.Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance.Insulin sensitivity and metabolic flexibility following exercise training among different obese insulin-resistant phenotypes.Acute exercise remodels mitochondrial membrane interactions in mouse skeletal muscle.Role of mitofusin 2 (Mfn2) in controlling cellular proliferation.Mitofusin-2 prevents skeletal muscle wasting in cancer cachexia.Therapeutic potential of pterostilbene against pancreatic beta-cell apoptosis mediated through Nrf2.The interplay between mitochondrial dynamics and mitophagyResistance to type 2 diabetes mellitus: a matter of hormesis?Mitochondrial alteration in type 2 diabetes and obesity: an epigenetic link.Diet impact on mitochondrial bioenergetics and dynamics.
P2860
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P2860
Subjects with early-onset type 2 diabetes show defective activation of the skeletal muscle PGC-1{alpha}/Mitofusin-2 regulatory pathway in response to physical activity
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Subjects with early-onset type ...... response to physical activity
@ast
Subjects with early-onset type ...... response to physical activity
@en
type
label
Subjects with early-onset type ...... response to physical activity
@ast
Subjects with early-onset type ...... response to physical activity
@en
prefLabel
Subjects with early-onset type ...... response to physical activity
@ast
Subjects with early-onset type ...... response to physical activity
@en
P2093
P2860
P50
P356
P1433
P1476
Subjects with early-onset type ...... response to physical activity
@en
P2093
Antonio Zorzano
Chiara Chiellini
Francis Finucane
Hood Thabit
Imad Brema
John J Nolan
Marc Liesa
Nicole Burns
P2860
P304
P356
10.2337/DC09-1305
P407
P577
2009-12-23T00:00:00Z