DNMT3L modulates significant and distinct flanking sequence preference for DNA methylation by DNMT3A and DNMT3B in vivo. - Wikidata - awgldk - TriplyDB

DNMT3L modulates significant and distinct flanking sequence preference for DNA methylation by DNMT3A and DNMT3B in vivo.

DNMT3L modulates significant and distinct flanking sequence preference for DNA methylation by DNMT3A and DNMT3B in vivo.

http://www.wikidata.org/entity/Q33691458

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The R882H DNMT3A mutation associated with AML dominantly inhibits wild-type DNMT3A by blocking its ability to form active tetramers Targeting the epigenome in lung cancer: expanding approaches to epigenetic therapy Epigenetic Research of Neurodegenerative Disorders Using Patient iPSC-Based Models Turning over DNA methylation in the mind The specification of imprints in mammals Dnmt3b Prefers Germ Line Genes and Centromeric Regions: Lessons from the ICF Syndrome and Cancer and Implications for Diseases The de novo DNA methyltransferase DNMT3A in development and cancer Identification of genomic features in environmentally induced epigenetic transgenerational inherited sperm epimutations Inactive DNMT3B splice variants modulate de novo DNA methylation Modulation of Dnmt3b function in vitro by interactions with Dnmt3L, Dnmt3a and Dnmt3b splice variants Epigenetic Guardian: A Review of the DNA Methyltransferase DNMT3A in Acute Myeloid Leukaemia and Clonal Haematopoiesis.Approaches to enzyme and substrate design of the murine Dnmt3a DNA methyltransferase.Critical period of nonpromoter DNA methylation acquisition during prenatal male germ cell development.Genomic distribution and inter-sample variation of non-CpG methylation across human cell types.Dynamic stage-specific changes in imprinted differentially methylated regions during early mammalian development and prevalence of non-CpG methylation in oocytes GC skew at the 5' and 3' ends of human genes links R-loop formation to epigenetic regulation and transcription termination DNMT3A in haematological malignancies.Epigenetic regulation of pluripotency and differentiation Epigenetic regulation in neural crest development.Mouse oocyte methylomes at base resolution reveal genome-wide accumulation of non-CpG methylation and role of DNA methyltransferases.Association between DNA methyltransferases 3B gene polymorphisms and the susceptibility to acute myeloid leukemia in Chinese Han population.Epigenetic alterations at genomic loci modified by gene targeting in Arabidopsis thaliana.On the sequence-directed nature of human gene mutation: the role of genomic architecture and the local DNA sequence environment in mediating gene mutations underlying human inherited disease.Methylation of L1Hs promoters is lower on the inactive X, has a tendency of being higher on autosomes in smaller genomes and shows inter-individual variability at some loci.Base-resolution analyses of sequence and parent-of-origin dependent DNA methylation in the mouse genome.Risk-association of DNA methyltransferases polymorphisms with gastric cancer in the Southern Chinese population.Mutations in DNA methyltransferase (DNMT3A) observed in acute myeloid leukemia patients disrupt processive methylation PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia.DNA and histone methylation in gastric carcinogenesis Genomic responses to hepatitis B virus (HBV) infection in primary human hepatocytes.Functions of DNA methyltransferase 3-like in germ cells and beyond.Insights into the epigenetic mechanisms controlling pancreatic carcinogenesis.Cooperative DNA binding and protein/DNA fiber formation increases the activity of the Dnmt3a DNA methyltransferase Functional aspects of cytidine-guanosine dinucleotides and their locations in genes.DNA methylation: a new twist in the tail.Genome-wide profiling of DNA methylation reveals preferred sequences of DNMTs in hepatocellular carcinoma cells.Establishment and functions of DNA methylation in the germline.DNA Hypomethylating Drugs in Cancer Therapy.DNA methyltransferase-3 like protein expression in various histological types of testicular germ cell tumor.Proximal recognition sites facilitate intrasite hopping by DNA adenine methyltransferase: mechanistic exploration of epigenetic gene regulation

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P2860

DNMT3L modulates significant and distinct flanking sequence preference for DNA methylation by DNMT3A and DNMT3B in vivo.

http://www.wikidata.org/entity/Q33691458

description

2010 nî lūn-bûn

@nan

2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

@wuu

name

DNMT3L modulates significant a ...... by DNMT3A and DNMT3B in vivo.

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DNMT3L modulates significant a ...... by DNMT3A and DNMT3B in vivo.

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DNMT3L modulates significant a ...... by DNMT3A and DNMT3B in vivo.

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DNMT3L modulates significant a ...... by DNMT3A and DNMT3B in vivo.

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JOURNAL.PGEN.1001106

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DNMT3L modulates significant a ...... n by DNMT3A and DNMT3B in vivo

@en

P2093

Amir H Moarefi

http://www.w3.org/2001/XMLSchema#string

Bethany L Wienholz

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Catherine A Gordon

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Paul A Ginno

http://www.w3.org/2001/XMLSchema#string

P2860

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene

EUKARYOTIC CYTOSINE METHYLTRANSFERASES

A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation

A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints

UHRF1 plays a role in maintaining DNA methylation in mammalian cells

Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain

Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation

Comprehensive analysis of CpG islands in human chromosomes 21 and 22

The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a

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e1001106

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10.1371/JOURNAL.PGEN.1001106

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9

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6

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Michael S Kareta

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2010-09-09T00:00:00Z

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46256518

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20838592

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P921

DNA methylation

P932

2936528

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